BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 11959808)

  • 1. Resolution of P-glycoprotein and non-P-glycoprotein effects on drug permeability using intestinal tissues from mdr1a (-/-) mice.
    Stephens RH; O'Neill CA; Bennett J; Humphrey M; Henry B; Rowland M; Warhurst G
    Br J Pharmacol; 2002 Apr; 135(8):2038-46. PubMed ID: 11959808
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Region-dependent modulation of intestinal permeability by drug efflux transporters: in vitro studies in mdr1a(-/-) mouse intestine.
    Stephens RH; Tanianis-Hughes J; Higgs NB; Humphrey M; Warhurst G
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1095-101. PubMed ID: 12438532
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Predicting P-glycoprotein effects on oral absorption: correlation of transport in Caco-2 with drug pharmacokinetics in wild-type and mdr1a(-/-) mice in vivo.
    Collett A; Tanianis-Hughes J; Hallifax D; Warhurst G
    Pharm Res; 2004 May; 21(5):819-26. PubMed ID: 15180340
    [TBL] [Abstract][Full Text] [Related]  

  • 4. (R)-[(11)C]verapamil is selectively transported by murine and human P-glycoprotein at the blood-brain barrier, and not by MRP1 and BCRP.
    Römermann K; Wanek T; Bankstahl M; Bankstahl JP; Fedrowitz M; Müller M; Löscher W; Kuntner C; Langer O
    Nucl Med Biol; 2013 Oct; 40(7):873-8. PubMed ID: 23845421
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Homozygous disruption of the mdrla P-glycoprotein gene affects blood-nerve barrier function in mice administered with neurotoxic drugs.
    Saito T; Zhang ZJ; Ohtsubo T; Noda I; Shibamori Y; Yamamoto T; Saito H
    Acta Otolaryngol; 2001 Sep; 121(6):735-42. PubMed ID: 11678173
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier.
    Rao VV; Dahlheimer JL; Bardgett ME; Snyder AZ; Finch RA; Sartorelli AC; Piwnica-Worms D
    Proc Natl Acad Sci U S A; 1999 Mar; 96(7):3900-5. PubMed ID: 10097135
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier.
    Cisternino S; Mercier C; Bourasset F; Roux F; Scherrmann JM
    Cancer Res; 2004 May; 64(9):3296-301. PubMed ID: 15126373
    [TBL] [Abstract][Full Text] [Related]  

  • 8. P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.
    Yang JJ; Milton MN; Yu S; Liao M; Liu N; Wu JT; Gan L; Balani SK; Lee FW; Prakash S; Xia CQ
    Drug Metab Lett; 2010 Dec; 4(4):201-12. PubMed ID: 20670210
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical role for P-glycoprotein expression in hematopoietic cells in the FVB.Mdr1a(-/-) model of colitis.
    Staley EM; Dimmitt RA; Schoeb TR; Tanner SM; Lorenz RG
    J Pediatr Gastroenterol Nutr; 2011 Dec; 53(6):666-73. PubMed ID: 21681110
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice.
    van Asperen J; Schinkel AH; Beijnen JH; Nooijen WJ; Borst P; van Tellingen O
    J Natl Cancer Inst; 1996 Jul; 88(14):994-9. PubMed ID: 8667431
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The antiepileptic drug mephobarbital is not transported by P-glycoprotein or multidrug resistance protein 1 at the blood-brain barrier: a positron emission tomography study.
    Mairinger S; Bankstahl JP; Kuntner C; Römermann K; Bankstahl M; Wanek T; Stanek J; Löscher W; Müller M; Erker T; Langer O
    Epilepsy Res; 2012 Jun; 100(1-2):93-103. PubMed ID: 22342565
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.
    Yu XY; Lin SG; Chen X; Zhou ZW; Liang J; Duan W; Chowbay B; Wen JY; Chan E; Cao J; Li CG; Zhou SF
    Curr Drug Metab; 2007 May; 8(4):365-78. PubMed ID: 17504224
    [TBL] [Abstract][Full Text] [Related]  

  • 13. What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine.
    Ogihara T; Kamiya M; Ozawa M; Fujita T; Yamamoto A; Yamashita S; Ohnishi S; Isomura Y
    Drug Metab Pharmacokinet; 2006 Jun; 21(3):238-44. PubMed ID: 16858128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intestinal transport of irinotecan in Caco-2 cells and MDCK II cells overexpressing efflux transporters Pgp, cMOAT, and MRP1.
    Luo FR; Paranjpe PV; Guo A; Rubin E; Sinko P
    Drug Metab Dispos; 2002 Jul; 30(7):763-70. PubMed ID: 12065434
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The systemic exposure of an N-methyl-D-aspartate receptor antagonist is limited in mice by the P-glycoprotein and breast cancer resistance protein efflux transporters.
    Polli JW; Baughman TM; Humphreys JE; Jordan KH; Mote AL; Webster LO; Barnaby RJ; Vitulli G; Bertolotti L; Read KD; Serabjit-Singh CJ
    Drug Metab Dispos; 2004 Jul; 32(7):722-6. PubMed ID: 15205387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multidrug resistance-associated protein: a protein distinct from P-glycoprotein involved in cytotoxic drug expulsion.
    Barrand MA; Bagrij T; Neo SY
    Gen Pharmacol; 1997 May; 28(5):639-45. PubMed ID: 9184795
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT).
    Guo A; Marinaro W; Hu P; Sinko PJ
    Drug Metab Dispos; 2002 Apr; 30(4):457-63. PubMed ID: 11901101
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients.
    Legrand O; Simonin G; Perrot JY; Zittoun R; Marie JP
    Blood; 1998 Jun; 91(12):4480-8. PubMed ID: 9616142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Altered drug disposition of the platelet activating factor antagonist apafant in mdr1a knockout mice.
    Leusch A; Volz A; Müller G; Wagner A; Sauer A; Greischel A; Roth W
    Eur J Pharm Sci; 2002 Aug; 16(3):119-28. PubMed ID: 12128165
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple-knockout) and wild-type mice.
    Marchetti S; de Vries NA; Buckle T; Bolijn MJ; van Eijndhoven MA; Beijnen JH; Mazzanti R; van Tellingen O; Schellens JH
    Mol Cancer Ther; 2008 Aug; 7(8):2280-7. PubMed ID: 18723475
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.