295 related articles for article (PubMed ID: 11959864)
1. DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis.
Buhman KK; Smith SJ; Stone SJ; Repa JJ; Wong JS; Knapp FF; Burri BJ; Hamilton RL; Abumrad NA; Farese RV
J Biol Chem; 2002 Jul; 277(28):25474-9. PubMed ID: 11959864
[TBL] [Abstract][Full Text] [Related]
2. Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat.
Hung YH; Carreiro AL; Buhman KK
Biochim Biophys Acta Mol Cell Biol Lipids; 2017 Jun; 1862(6):600-614. PubMed ID: 28249764
[TBL] [Abstract][Full Text] [Related]
3. DGAT1 deficiency disrupts lysosome function in enterocytes during dietary fat absorption.
Hung YH; Buhman KK
Biochim Biophys Acta Mol Cell Biol Lipids; 2019 Apr; 1864(4):587-595. PubMed ID: 30342099
[TBL] [Abstract][Full Text] [Related]
4. Roles of Acyl-CoA:Diacylglycerol Acyltransferases 1 and 2 in Triacylglycerol Synthesis and Secretion in Primary Hepatocytes.
Li C; Li L; Lian J; Watts R; Nelson R; Goodwin B; Lehner R
Arterioscler Thromb Vasc Biol; 2015 May; 35(5):1080-91. PubMed ID: 25792450
[TBL] [Abstract][Full Text] [Related]
5. Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans.
Maciejewski BS; LaPerle JL; Chen D; Ghosh A; Zavadoski WJ; McDonald TS; Manion TB; Mather D; Patterson TA; Hanna M; Watkins S; Gibbs EM; Calle RA; Steppan CM
Am J Physiol Gastrointest Liver Physiol; 2013 Jun; 304(11):G958-69. PubMed ID: 23558010
[TBL] [Abstract][Full Text] [Related]
6. Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism.
Yen CE; Nelson DW; Yen MI
J Lipid Res; 2015 Mar; 56(3):489-501. PubMed ID: 25231105
[TBL] [Abstract][Full Text] [Related]
7. Intestine-specific expression of acyl CoA:diacylglycerol acyltransferase 1 reverses resistance to diet-induced hepatic steatosis and obesity in Dgat1-/- mice.
Lee B; Fast AM; Zhu J; Cheng JX; Buhman KK
J Lipid Res; 2010 Jul; 51(7):1770-80. PubMed ID: 20147738
[TBL] [Abstract][Full Text] [Related]
8. Diacylglycerol acyltransferase 1/2 inhibition induces dysregulation of fatty acid metabolism and leads to intestinal barrier failure and diarrhea in mice.
Takemoto K; Fukasaka Y; Yoshimoto R; Nambu H; Yukioka H
Physiol Rep; 2020 Aug; 8(15):e14542. PubMed ID: 32786057
[TBL] [Abstract][Full Text] [Related]
9. Acylation of acylglycerols by acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1). Functional importance of DGAT1 in the intestinal fat absorption.
Cheng D; Iqbal J; Devenny J; Chu CH; Chen L; Dong J; Seethala R; Keim WJ; Azzara AV; Lawrence RM; Pelleymounter MA; Hussain MM
J Biol Chem; 2008 Oct; 283(44):29802-11. PubMed ID: 18768481
[TBL] [Abstract][Full Text] [Related]
10. The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters.
Yen CL; Monetti M; Burri BJ; Farese RV
J Lipid Res; 2005 Jul; 46(7):1502-11. PubMed ID: 15834126
[TBL] [Abstract][Full Text] [Related]
11. Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying.
Ables GP; Yang KJ; Vogel S; Hernandez-Ono A; Yu S; Yuen JJ; Birtles S; Buckett LK; Turnbull AV; Goldberg IJ; Blaner WS; Huang LS; Ginsberg HN
J Lipid Res; 2012 Nov; 53(11):2364-79. PubMed ID: 22911105
[TBL] [Abstract][Full Text] [Related]
12. The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes.
Chitraju C; Walther TC; Farese RV
J Lipid Res; 2019 Jun; 60(6):1112-1120. PubMed ID: 30936184
[TBL] [Abstract][Full Text] [Related]
13. Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Sachdev V; Leopold C; Bauer R; Patankar JV; Iqbal J; Obrowsky S; Boverhof R; Doktorova M; Scheicher B; Goeritzer M; Kolb D; Turnbull AV; Zimmer A; Hoefler G; Hussain MM; Groen AK; Kratky D
Biochim Biophys Acta; 2016 Sep; 1861(9 Pt A):1132-1141. PubMed ID: 27344248
[TBL] [Abstract][Full Text] [Related]
14. Pharmacological characterization of [trans-5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl]acetic acid monobenzenesulfonate (JTT-553), a novel acyl CoA:diacylglycerol transferase (DGAT) 1 inhibitor.
Tomimoto D; Okuma C; Ishii Y; Akiyama Y; Ohta T; Kakutani M; Ohkuma Y; Ogawa N
Biol Pharm Bull; 2015; 38(2):263-9. PubMed ID: 25747985
[TBL] [Abstract][Full Text] [Related]
15. Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice.
Chandak PG; Obrowsky S; Radovic B; Doddapattar P; Aflaki E; Kratzer A; Doshi LS; Povoden S; Ahammer H; Hoefler G; Levak-Frank S; Kratky D
Biochim Biophys Acta; 2011 Dec; 1811(12):1011-20. PubMed ID: 21924378
[TBL] [Abstract][Full Text] [Related]
16. Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.
Stone SJ; Myers HM; Watkins SM; Brown BE; Feingold KR; Elias PM; Farese RV
J Biol Chem; 2004 Mar; 279(12):11767-76. PubMed ID: 14668353
[TBL] [Abstract][Full Text] [Related]
17. Diacylglycerol acyltransferase-2 (DGAT2) and monoacylglycerol acyltransferase-2 (MGAT2) interact to promote triacylglycerol synthesis.
Jin Y; McFie PJ; Banman SL; Brandt C; Stone SJ
J Biol Chem; 2014 Oct; 289(41):28237-48. PubMed ID: 25164810
[TBL] [Abstract][Full Text] [Related]
18. Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes.
Selvaraj R; Zehnder SV; Watts R; Lian J; Das C; Nelson R; Lehner R
Biochim Biophys Acta Mol Cell Biol Lipids; 2023 Oct; 1868(10):159376. PubMed ID: 37516308
[TBL] [Abstract][Full Text] [Related]
19. Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1.
Yamazaki T; Sasaki E; Kakinuma C; Yano T; Miura S; Ezaki O
J Biol Chem; 2005 Jun; 280(22):21506-14. PubMed ID: 15797871
[TBL] [Abstract][Full Text] [Related]
20. Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1.
Chen HC; Smith SJ; Ladha Z; Jensen DR; Ferreira LD; Pulawa LK; McGuire JG; Pitas RE; Eckel RH; Farese RV
J Clin Invest; 2002 Apr; 109(8):1049-55. PubMed ID: 11956242
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
