BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 11961054)

  • 1. Correlation of neurokinin (NK) 1 receptor occupancy in gerbil striatum with behavioral effects of NK1 antagonists.
    Duffy RA; Varty GB; Morgan CA; Lachowicz JE
    J Pharmacol Exp Ther; 2002 May; 301(2):536-42. PubMed ID: 11961054
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist.
    Ballard TM; Sänger S; Higgins GA
    Eur J Pharmacol; 2001 Feb; 412(3):255-64. PubMed ID: 11166289
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists.
    Rupniak NM; Tattersall FD; Williams AR; Rycroft W; Carlson EJ; Cascieri MA; Sadowski S; Ber E; Hale JJ; Mills SG; MacCoss M; Seward E; Huscroft I; Owen S; Swain CJ; Hill RG; Hargreaves RJ
    Eur J Pharmacol; 1997 May; 326(2-3):201-9. PubMed ID: 9196273
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists.
    Varty GB; Cohen-Williams ME; Morgan CA; Pylak U; Duffy RA; Lachowicz JE; Carey GJ; Coffin VL
    Neuropsychopharmacology; 2002 Sep; 27(3):371-9. PubMed ID: 12225694
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [3H]GR205171 displays similar NK1 receptor binding profile in gerbil and human brain.
    Griffante C; Carletti R; Andreetta F; Corsi M
    Br J Pharmacol; 2006 May; 148(1):39-45. PubMed ID: 16501582
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neurokinin 1 receptor antagonists: correlation between in vitro receptor interaction and in vivo efficacy.
    Lindström E; von Mentzer B; Påhlman I; Ahlstedt I; Uvebrant A; Kristensson E; Martinsson R; Novén A; de Verdier J; Vauquelin G
    J Pharmacol Exp Ther; 2007 Sep; 322(3):1286-93. PubMed ID: 17575073
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacological characterization of T-2328, 2-fluoro-4'-methoxy-3'-[[[(2S,3S)-2-phenyl-3-piperidinyl]amino]methyl]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride, as a brain-penetrating antagonist of tachykinin NK1 receptor.
    Watanabe Y; Asai H; Ishii T; Kiuchi S; Okamoto M; Taniguchi H; Nagasaki M; Saito A
    J Pharmacol Sci; 2008 Jan; 106(1):121-7. PubMed ID: 18187929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The pharmacology of GR203040, a novel, potent and selective non-peptide tachykinin NK1 receptor antagonist.
    Beattie DT; Beresford IJ; Connor HE; Marshall FH; Hawcock AB; Hagan RM; Bowers J; Birch PJ; Ward P
    Br J Pharmacol; 1995 Dec; 116(8):3149-57. PubMed ID: 8719789
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SSR240600 [(R)-2-(1-[2-[4-[2-[3,5-bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]-4-piperidinyl)-2-methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin 1 receptor: II. Neurochemical and behavioral characterization.
    Steinberg R; Alonso R; Rouquier L; Desvignes C; Michaud JC; Cudennec A; Jung M; Simiand J; Griebel G; Emonds-Alt X; Le Fur G; Soubrié P
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1180-8. PubMed ID: 12438542
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The potency of the novel tachykinin receptor antagonist CGP49823 at rat and gerbil motoneurones in vitro.
    Pozza MF; Olpe HR; Ofner S; Schoeffel C; Evans RH
    Eur J Pharmacol; 1998 Jan; 342(2-3):203-8. PubMed ID: 9548386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Senktide-induced gerbil foot tapping behaviour is blocked by selective tachykinin NK1 and NK3 receptor antagonists.
    Sundqvist M; Kristensson E; Adolfsson R; Leffler A; Ahlstedt I; Engberg S; Drmota T; Sigfridsson K; Jussila R; de Verdier J; Novén A; Johansson A; Påhlman I; von Mentzer B; Lindström E
    Eur J Pharmacol; 2007 Dec; 577(1-3):78-86. PubMed ID: 17920583
    [TBL] [Abstract][Full Text] [Related]  

  • 12. S41744, a dual neurokinin (NK)1 receptor antagonist and serotonin (5-HT) reuptake inhibitor with potential antidepressant properties: a comparison to aprepitant (MK869) and paroxetine.
    Millan MJ; Dekeyne A; Gobert A; Mannoury la Cour C; Brocco M; Rivet JM; Di Cara B; Lejeune F; Cremers TI; Flik G; de Jong TR; Olivier B; de Nanteuil G
    Eur Neuropsychopharmacol; 2010 Sep; 20(9):599-621. PubMed ID: 20483567
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate.
    Di Fabio R; Alvaro G; Braggio S; Carletti R; Gerrard PA; Griffante C; Marchioro C; Pozzan A; Melotto S; Poffe A; Piccoli L; Ratti E; Tranquillini E; Trower M; Spada S; Corsi M
    Bioorg Med Chem; 2013 Nov; 21(21):6264-73. PubMed ID: 24075145
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SSR240600 [(R)-2-(1-[2-[4-[2-[3,5-bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]- 4-piperidinyl)-2-methylpropanamide], a centrally active nonpeptide antagonist of the tachykinin neurokinin-1 receptor: I. biochemical and pharmacological characterization.
    Emonds-Alt X; Proietto V; Steinberg R; Oury-Donat F; Vigé X; Vilain P; Naline E; Daoui S; Advenier C; Le Fur G; Maffrand JP; Soubrié P; Pascal M
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1171-9. PubMed ID: 12438541
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the binding and activity of a high affinity, pseudoirreversible morpholino tachykinin NK1 receptor antagonist.
    Cascieri MA; Ber E; Fong TM; Hale JJ; Tang F; Shiao LL; Mills SG; MacCoss M; Sadowski S; Tota MR; Strader CD
    Eur J Pharmacol; 1997 May; 325(2-3):253-61. PubMed ID: 9163573
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of two potential NK1-receptor ligands using [1-11C]ethyl iodide and [1-11C]propyl iodide and initial PET-imaging.
    Syvänen S; Eriksson J; Genchel T; Lindhe O; Antoni G; Långström B
    BMC Med Imaging; 2007 Jul; 7():6. PubMed ID: 17663770
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacological properties of FK886, a new, centrally active neurokinin-1 receptor antagonist.
    Yoshino-Furukawa T; Maeda Y; Kikuchi A; Sakuma H; Imazumi K; Yamakuni H; Sogabe H; Matsuo M; Manda T; Uchida W
    Biol Pharm Bull; 2013; 36(1):76-81. PubMed ID: 23302639
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1 ) receptor in assays for antidepressant and anxiolytic drugs.
    Rupniak NM; Carlson EJ; Webb JK; Harrison T; Porsolt RD; Roux S; de Felipe C; Hunt SP; Oates B; Wheeldon A
    Behav Pharmacol; 2001 Nov; 12(6-7):497-508. PubMed ID: 11742144
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rolapitant (SCH 619734): a potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets.
    Duffy RA; Morgan C; Naylor R; Higgins GA; Varty GB; Lachowicz JE; Parker EM
    Pharmacol Biochem Behav; 2012 Jul; 102(1):95-100. PubMed ID: 22497992
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 13.