BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 11965542)

  • 1. The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP.
    Izutsu K; Kurokawa M; Imai Y; Ichikawa M; Asai T; Maki K; Mitani K; Hirai H
    Oncogene; 2002 Apr; 21(17):2695-703. PubMed ID: 11965542
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mechanisms of leukemogenesis by AML1/EVI-1.
    Mitani K
    Oncogene; 2004 May; 23(24):4263-9. PubMed ID: 15156182
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The AML1/Evi-1 fusion protein in the t(3;21) translocation exhibits transforming activity on Rat1 fibroblasts with dependence on the Evi-1 sequence.
    Kurokawa M; Ogawa S; Tanaka T; Mitani K; Yazaki Y; Witte ON; Hirai H
    Oncogene; 1995 Sep; 11(5):833-40. PubMed ID: 7675444
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias.
    Tanaka T; Mitani K; Kurokawa M; Ogawa S; Tanaka K; Nishida J; Yazaki Y; Shibata Y; Hirai H
    Mol Cell Biol; 1995 May; 15(5):2383-92. PubMed ID: 7739522
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.
    Lo Coco F; Pisegna S; Diverio D
    Haematologica; 1997; 82(3):364-70. PubMed ID: 9234595
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanism of blastic crisis in chronic myelocytic leukemia.
    Mitani K
    Leukemia; 1997 Apr; 11 Suppl 3():503-5. PubMed ID: 9209439
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP.
    Nitta E; Izutsu K; Yamaguchi Y; Imai Y; Ogawa S; Chiba S; Kurokawa M; Hirai H
    Oncogene; 2005 Sep; 24(40):6165-73. PubMed ID: 15897867
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2beta(CBFbeta) in the nucleus more efficiently than wild-type AML1.
    Tanaka K; Tanaka T; Kurokawa M; Imai Y; Ogawa S; Mitani K; Yazaki Y; Hirai H
    Blood; 1998 Mar; 91(5):1688-99. PubMed ID: 9473235
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.
    Kurokawa M; Mitani K; Imai Y; Ogawa S; Yazaki Y; Hirai H
    Blood; 1998 Dec; 92(11):4003-12. PubMed ID: 9834202
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rearrangements of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: in vitro and in vivo studies.
    Zent C; Rowley JD; Nucifora G
    Leukemia; 1997 Apr; 11 Suppl 3():273-8. PubMed ID: 9209363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA-binding domain of AML1, expressed in t(8;21) and t(3;21) myeloid leukemias, inhibits PEBP2/CBF DNA-binding but is not sufficient to transform 32D cl3 myeloid cells.
    Britos-Bray M; Sacchi N; Friedman AD
    Leukemia; 1996 Jun; 10(6):984-90. PubMed ID: 8667656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of the AML1 proto-oncoprotein in NIH3T3 cells leads to neoplastic transformation depending on the DNA-binding and transactivational potencies.
    Kurokawa M; Tanaka T; Tanaka K; Ogawa S; Mitani K; Yazaki Y; Hirai H
    Oncogene; 1996 Feb; 12(4):883-92. PubMed ID: 8632911
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The leukemia-associated transcription repressor AML1/MDS1/EVI1 requires CtBP to induce abnormal growth and differentiation of murine hematopoietic cells.
    Senyuk V; Chakraborty S; Mikhail FM; Zhao R; Chi Y; Nucifora G
    Oncogene; 2002 May; 21(20):3232-40. PubMed ID: 12082639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AML1-ETO decreases ETO-2 (MTG16) interactions with nuclear receptor corepressor, an effect that impairs granulocyte differentiation.
    IbaƱez V; Sharma A; Buonamici S; Verma A; Kalakonda S; Wang J; Kadkol S; Saunthararajah Y
    Cancer Res; 2004 Jul; 64(13):4547-54. PubMed ID: 15231665
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RUNX1/EVI1, which blocks myeloid differentiation, inhibits CCAAT-enhancer binding protein alpha function.
    Tokita K; Maki K; Mitani K
    Cancer Sci; 2007 Nov; 98(11):1752-7. PubMed ID: 17894555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2.
    Kohzaki H; Ito K; Huang G; Wee HJ; Murakami Y; Ito Y
    Oncogene; 1999 Jul; 18(28):4055-62. PubMed ID: 10435586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An acute myeloid leukemia gene, AML1, regulates transcriptional activation and hemopoietic myeloid cell differentiation antagonistically by two alternative spliced forms.
    Tanaka T; Tanaka K; Ogawa S; Kurokawa M; Mitani K; Yazaki Y; Shibata Y; Hirai H
    Leukemia; 1997 Apr; 11 Suppl 3():299-302. PubMed ID: 9209372
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.
    Mitani K; Ogawa S; Tanaka T; Miyoshi H; Kurokawa M; Mano H; Yazaki Y; Ohki M; Hirai H
    EMBO J; 1994 Feb; 13(3):504-10. PubMed ID: 8313895
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression and regulation of the evi-1 gene in the human factor-dependent leukemia cell line, UCSD/AML1.
    Oval J; Smedsrud M; Taetle R
    Leukemia; 1992 May; 6(5):446-51. PubMed ID: 1593910
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A distinct epigenetic signature at targets of a leukemia protein.
    Rossetti S; Hoogeveen AT; Liang P; Stanciu C; van der Spek P; Sacchi N
    BMC Genomics; 2007 Feb; 8():38. PubMed ID: 17266773
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.