BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 11966436)

  • 1. The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside.
    Pankiewicz KW; Watanabe KA; Lesiak-Watanabe K; Goldstein BM; Jayaram HN
    Curr Med Chem; 2002 Apr; 9(7):733-41. PubMed ID: 11966436
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin.
    Gharehbaghi K; Sreenath A; Hao Z; Paull KD; Szekeres T; Cooney DA; Krohn K; Jayaram HN
    Biochem Pharmacol; 1994 Oct; 48(7):1413-9. PubMed ID: 7945441
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isosteric analogues of nicotinamide adenine dinucleotide derived from furanfurin, thiophenfurin, and selenophenfurin as mammalian inosine monophosphate dehydrogenase (type I and II) inhibitors.
    Franchetti P; Cappellacci L; Perlini P; Jayaram HN; Butler A; Schneider BP; Collart FR; Huberman E; Grifantini M
    J Med Chem; 1998 May; 41(10):1702-7. PubMed ID: 9572896
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Studies on the mechanism of action of benzamide riboside: a novel inhibitor of IMP dehydrogenase.
    Gharehbaghi K; Grünberger W; Jayaram HN
    Curr Med Chem; 2002 Apr; 9(7):743-8. PubMed ID: 11966437
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents.
    Franchetti P; Grifantini M
    Curr Med Chem; 1999 Jul; 6(7):599-614. PubMed ID: 10390603
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel nicotinamide adenine dinucleotide analogues as potential anticancer agents: quest for specific inhibition of inosine monophosphate dehydrogenase.
    Pankiewicz KW
    Pharmacol Ther; 1997; 76(1-3):89-100. PubMed ID: 9535171
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity.
    Cooney DA; Jayaram HN; Glazer RI; Kelley JA; Marquez VE; Gebeyehu G; Van Cott AC; Zwelling LA; Johns DG
    Adv Enzyme Regul; 1983; 21():271-303. PubMed ID: 6152729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis.
    Jayaram HN; Cooney DA; Grusch M; Krupitza G
    Curr Med Chem; 1999 Jul; 6(7):561-74. PubMed ID: 10390601
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase.
    Gebeyehu G; Marquez VE; Van Cott A; Cooney DA; Kelley JA; Jayaram HN; Ahluwalia GS; Dion RL; Wilson YA; Johns DG
    J Med Chem; 1985 Jan; 28(1):99-105. PubMed ID: 2856943
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by the synthetic "C" nucleoside analogs, tiazofurin and selenazofurin. A new strategy for cancer chemotherapy.
    Berger NA; Berger SJ; Catino DM; Petzold SJ; Robins RK
    J Clin Invest; 1985 Feb; 75(2):702-9. PubMed ID: 3919063
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of isosteric analogues of nicotinamide adenine dinucleotide containing C-nucleotide of nicotinamide or picolinamide.
    Pankiewicz KW; Zeidler J; Ciszewski LA; Bell JE; Goldstein BM; Jayaram HN; Watanabe KA
    J Med Chem; 1993 Jun; 36(13):1855-9. PubMed ID: 8099976
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase.
    Yalowitz JA; Jayaram HN
    Curr Med Chem; 2002 Apr; 9(7):749-58. PubMed ID: 11966438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dehydrogenase binding by tiazofurin anabolites.
    Goldstein BM; Bell JE; Marquez VE
    J Med Chem; 1990 Apr; 33(4):1123-7. PubMed ID: 1969483
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism of the novel IMP dehydrogenase inhibitor benzamide riboside.
    Jäger W; Salamon A; Szekeres T
    Curr Med Chem; 2002 Apr; 9(7):781-6. PubMed ID: 11966442
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.
    Chen L; Gao G; Felczak K; Bonnac L; Patterson SE; Wilson D; Bennett EM; Jayaram HN; Hedstrom L; Pankiewicz KW
    J Med Chem; 2007 Nov; 50(23):5743-51. PubMed ID: 17958343
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Furanfurin and thiophenfurin: two novel tiazofurin analogues. Synthesis, structure, antitumor activity, and interactions with inosine monophosphate dehydrogenase.
    Franchetti P; Cappellacci L; Grifantini M; Barzi A; Nocentini G; Yang H; O'Connor A; Jayaram HN; Carrell C; Goldstein BM
    J Med Chem; 1995 Sep; 38(19):3829-37. PubMed ID: 7562914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of nonhydrolyzable analogues of thiazole-4-carboxamide and benzamide adenine dinucleotide containing fluorine atom at the C2' of adenine nucleoside: induction of K562 differentiation and inosine monophosphate dehydrogenase inhibitory activity.
    Lesiak K; Watanabe KA; Majumdar A; Seidman M; Vanderveen K; Goldstein BM; Pankiewicz KW
    J Med Chem; 1997 Aug; 40(16):2533-8. PubMed ID: 9258359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NAD-analogues as potential anticancer agents: conformational restrictions as basis for selectivity.
    Pankiewicz KW; Zatorski A; Watanabe KA
    Acta Biochim Pol; 1996; 43(1):183-93. PubMed ID: 8790723
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relationships between the cytotoxicity of tiazofurin and its metabolism by cultured human lung cancer cells.
    Carney DN; Ahluwalia GS; Jayaram HN; Cooney DA; Johns DG
    J Clin Invest; 1985 Jan; 75(1):175-82. PubMed ID: 2856924
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase.
    Gharehbaghi K; Paull KD; Kelley JA; Barchi JJ; Marquez VE; Cooney DA; Monks A; Scudiero D; Krohn K; Jayaram HN
    Int J Cancer; 1994 Mar; 56(6):892-9. PubMed ID: 7907081
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.