BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 11967256)

  • 1. Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice.
    Agellon LB; Drover VA; Cheema SK; Gbaguidi GF; Walsh A
    J Biol Chem; 2002 Jun; 277(23):20131-4. PubMed ID: 11967256
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.
    Gbaguidi GF; Agellon LB
    Nucleic Acids Res; 2004; 32(3):1113-21. PubMed ID: 14960721
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cholesterol feeding of mice expressing cholesterol 7alpha-hydroxylase increases bile acid pool size despite decreased enzyme activity.
    Tiemann M; Han Z; Soccio R; Bollineni J; Shefer S; Sehayek E; Breslow JL
    Proc Natl Acad Sci U S A; 2004 Feb; 101(7):1846-51. PubMed ID: 14762172
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The atypical interaction of peroxisome proliferator-activated receptor alpha with liver X receptor alpha antagonizes the stimulatory effect of their respective ligands on the murine cholesterol 7alpha-hydroxylase gene promoter.
    Gbaguidi GF; Agellon LB
    Biochim Biophys Acta; 2002 Jul; 1583(2):229-36. PubMed ID: 12117567
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet.
    Chen JY; Levy-Wilson B; Goodart S; Cooper AD
    J Biol Chem; 2002 Nov; 277(45):42588-95. PubMed ID: 12202481
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).
    Chiang JY; Kimmel R; Stroup D
    Gene; 2001 Jan; 262(1-2):257-65. PubMed ID: 11179691
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.
    Chow EC; Magomedova L; Quach HP; Patel R; Durk MR; Fan J; Maeng HJ; Irondi K; Anakk S; Moore DD; Cummins CL; Pang KS
    Gastroenterology; 2014 Apr; 146(4):1048-59. PubMed ID: 24365583
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway.
    Gupta S; Stravitz RT; Dent P; Hylemon PB
    J Biol Chem; 2001 May; 276(19):15816-22. PubMed ID: 11278771
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification and characterization of cis-acting elements conferring insulin responsiveness on hamster cholesterol 7alpha-hydroxylase gene promoter.
    De Fabiani E; Crestani M; Marrapodi M; Pinelli A; Golfieri V; Galli G
    Biochem J; 2000 Apr; 347 Pt 1(Pt 1):147-54. PubMed ID: 10727413
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms.
    Cai SY; He H; Nguyen T; Mennone A; Boyer JL
    J Lipid Res; 2010 Aug; 51(8):2265-74. PubMed ID: 20338915
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of vitamin D receptor inhibition of cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes.
    Han S; Chiang JY
    Drug Metab Dispos; 2009 Mar; 37(3):469-78. PubMed ID: 19106115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene.
    Patel DD; Knight BL; Soutar AK; Gibbons GF; Wade DP
    Biochem J; 2000 Nov; 351 Pt 3(Pt 3):747-53. PubMed ID: 11042130
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The murine and human cholesterol 7alpha-hydroxylase gene promoters are differentially responsive to regulation by fatty acids mediated via peroxisome proliferator-activated receptor alpha.
    Cheema SK; Agellon LB
    J Biol Chem; 2000 Apr; 275(17):12530-6. PubMed ID: 10777541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An overlapping binding site in the CYP7A1 promoter allows activation of FXR to override the stimulation by LXRalpha.
    Shang Q; Pan L; Saumoy M; Chiang JY; Tint GS; Salen G; Xu G
    Am J Physiol Gastrointest Liver Physiol; 2007 Oct; 293(4):G817-23. PubMed ID: 17690173
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase.
    Miyake JH; Doung XD; Strauss W; Moore GL; Castellani LW; Curtiss LK; Taylor JM; Davis RA
    J Biol Chem; 2001 Jun; 276(26):23304-11. PubMed ID: 11323427
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Species-specific mechanisms for cholesterol 7alpha-hydroxylase (CYP7A1) regulation by drugs and bile acids.
    Handschin C; Gnerre C; Fraser DJ; Martinez-Jimenez C; Jover R; Meyer UA
    Arch Biochem Biophys; 2005 Feb; 434(1):75-85. PubMed ID: 15629111
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The stimulatory effect of LXRalpha is blocked by SHP despite the presence of a LXRalpha binding site in the rabbit CYP7A1 promoter.
    Shang Q; Pan L; Saumoy M; Chiang JY; Tint GS; Salen G; Xu G
    J Lipid Res; 2006 May; 47(5):997-1004. PubMed ID: 16489206
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.
    Song KH; Chiang JY
    Hepatology; 2006 Jan; 43(1):117-25. PubMed ID: 16323215
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dietary cholesterol stimulates CYP7A1 in rats because farnesoid X receptor is not activated.
    Xu G; Pan LX; Li H; Shang Q; Honda A; Shefer S; Bollineni J; Matsuzaki Y; Tint GS; Salen G
    Am J Physiol Gastrointest Liver Physiol; 2004 May; 286(5):G730-5. PubMed ID: 14684380
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids.
    Bramlett KS; Yao S; Burris TP
    Mol Genet Metab; 2000 Dec; 71(4):609-15. PubMed ID: 11136553
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.