BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 11985478)

  • 1. A trypanocidal phenazine derived from beta-lapachone.
    Neves-Pinto C; Malta VR; Pinto Mdo C; Santos RH; de Castro SL; Pinto AV
    J Med Chem; 2002 May; 45(10):2112-5. PubMed ID: 11985478
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of naphthofuranquinones with activity against Trypanosoma cruzi.
    Silva RS; Costa EM; Trindade UL; Teixeira DV; Pinto Mde C; Santos GL; Malta VR; De Simone CA; Pinto AV; de Castro SL
    Eur J Med Chem; 2006 Apr; 41(4):526-30. PubMed ID: 16500733
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.
    da Silva EN; Menna-Barreto RF; Pinto Mdo C; Silva RS; Teixeira DV; de Souza MC; De Simone CA; De Castro SL; Ferreira VF; Pinto AV
    Eur J Med Chem; 2008 Aug; 43(8):1774-80. PubMed ID: 18045742
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and anti-Trypanosoma cruzi activity of β-lapachone analogues.
    Ferreira SB; Salomão K; de Carvalho da Silva F; Pinto AV; Kaiser CR; Pinto AC; Ferreira VF; de Castro SL
    Eur J Med Chem; 2011 Jul; 46(7):3071-7. PubMed ID: 21450374
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Natural and synthetic naphthoquinones active against Trypanosoma cruzi: an initial step towards new drugs for Chagas disease.
    Salas CO; Faúndez M; Morello A; Maya JD; Tapia RA
    Curr Med Chem; 2011; 18(1):144-61. PubMed ID: 21110810
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
    Salas C; Tapia RA; Ciudad K; Armstrong V; Orellana M; Kemmerling U; Ferreira J; Maya JD; Morello A
    Bioorg Med Chem; 2008 Jan; 16(2):668-74. PubMed ID: 18029184
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and anti-Trypanosoma cruzi activity of new 3-phenylthio-nor-β-lapachone derivatives.
    Cardoso MFDC; Salomão K; Bombaça AC; da Rocha DR; da Silva FC; Cavaleiro JAS; de Castro SL; Ferreira VF
    Bioorg Med Chem; 2015 Aug; 23(15):4763-4768. PubMed ID: 26118339
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Trypanocidal activity of 5,6-dihydropyran-2-ones against free trypomastigotes forms of Trypanosoma cruzi.
    de Fátima A; Marquissolo C; de Albuquerque S; Carraro-Abrahão AA; Pilli RA
    Eur J Med Chem; 2006 Oct; 41(10):1210-3. PubMed ID: 16815596
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [The chemotherapy of Chagas disease].
    Stoppani AO
    Medicina (B Aires); 1999; 59 Suppl 2():147-65. PubMed ID: 10668258
    [TBL] [Abstract][Full Text] [Related]  

  • 10. On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
    da Silva Júnior EN; de Melo IM; Diogo EB; Costa VA; de Souza Filho JD; Valença WO; Camara CA; de Oliveira RN; de Araujo AS; Emery FS; dos Santos MR; de Simone CA; Menna-Barreto RF; de Castro SL
    Eur J Med Chem; 2012 Jun; 52():304-12. PubMed ID: 22483633
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of quinones derived from natural product komaroviquinone as anti-Trypanosoma cruzi agents.
    Suto Y; Nakajima-Shimada J; Yamagiwa N; Onizuka Y; Iwasaki G
    Bioorg Med Chem Lett; 2015 Aug; 25(15):2967-71. PubMed ID: 26037321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi.
    de Oliveira Filho GB; Cardoso MVO; Espíndola JWP; Oliveira E Silva DA; Ferreira RS; Coelho PL; Anjos PSD; Santos ES; Meira CS; Moreira DRM; Soares MBP; Leite ACL
    Eur J Med Chem; 2017 Dec; 141():346-361. PubMed ID: 29031078
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound.
    Lara LS; Moreira CS; Calvet CM; Lechuga GC; Souza RS; Bourguignon SC; Ferreira VF; Rocha D; Pereira MCS
    Eur J Med Chem; 2018 Jan; 144():572-581. PubMed ID: 29289882
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of 9-hydroxy-α- and 7-hydroxy-β-pyran naphthoquinones on Trypanosoma cruzi and structure-activity relationship studies.
    da Rochaa DR; de Souza AM; de Souza AC; Castro HC; Rodrigues CR; Menna-Barreto RF; de Castro SL; Ferreira VF
    Med Chem; 2014; 10(6):564-70. PubMed ID: 24372389
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety.
    Diogo EB; Dias GG; Rodrigues BL; Guimarães TT; Valença WO; Camara CA; de Oliveira RN; da Silva MG; Ferreira VF; de Paiva YG; Goulart MO; Menna-Barreto RF; de Castro SL; da Silva Júnior EN
    Bioorg Med Chem; 2013 Nov; 21(21):6337-48. PubMed ID: 24074878
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and Antitrypanosomal Profile of Novel Hydrazonoyl Derivatives.
    Santiago NN; de Alcântara GP; da Costa JS; Carvalho SA; Barbosa JMC; Salomão K; de Castro SL; Pereira HMG; da Silva EF
    Med Chem; 2020; 16(4):487-494. PubMed ID: 31309899
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2-Phenylaminonaphthoquinones and related compounds: synthesis, trypanocidal and cytotoxic activities.
    Sieveking I; Thomas P; Estévez JC; Quiñones N; Cuéllar MA; Villena J; Espinosa-Bustos C; Fierro A; Tapia RA; Maya JD; López-Muñoz R; Cassels BK; Estévez RJ; Salas CO
    Bioorg Med Chem; 2014 Sep; 22(17):4609-20. PubMed ID: 25127463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization and trypanocidal activity of a β-lapachone-containing drug carrier.
    Barbosa JMC; Nicoletti CD; da Silva PB; Melo TG; Futuro DO; Ferreira VF; Salomão K
    PLoS One; 2021; 16(3):e0246811. PubMed ID: 33661933
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.
    Carneiro PF; do Nascimento SB; Pinto AV; Pinto Mdo C; Lechuga GC; Santos DO; dos Santos Júnior HM; Resende JA; Bourguignon SC; Ferreira VF
    Bioorg Med Chem; 2012 Aug; 20(16):4995-5000. PubMed ID: 22795899
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular design aided by random forests and synthesis of potent trypanocidal agents as cruzain inhibitors for Chagas disease treatment.
    de Albuquerque S; Cianni L; de Vita D; Duque C; Gomes ASM; Gomes P; Laughton C; Leitão A; Montanari CA; Montanari R; Ribeiro JFR; da Silva JS; Teixeira C
    Chem Biol Drug Des; 2020 Sep; 96(3):948-960. PubMed ID: 33058457
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.