381 related articles for article (PubMed ID: 11987143)
1. HIV integrase as a target for antiviral chemotherapy.
Nair V
Rev Med Virol; 2002; 12(3):179-93. PubMed ID: 11987143
[TBL] [Abstract][Full Text] [Related]
2. Novel inhibitors of HIV integrase: the discovery of potential anti-HIV therapeutic agents.
Nair V
Curr Pharm Des; 2003; 9(31):2553-65. PubMed ID: 14529542
[TBL] [Abstract][Full Text] [Related]
3. HIV integrase inhibitors as therapeutic agents in AIDS.
Nair V; Chi G
Rev Med Virol; 2007; 17(4):277-95. PubMed ID: 17503547
[TBL] [Abstract][Full Text] [Related]
4. HIV type 1 integrase inhibitors: from basic research to clinical implications.
Jegede O; Babu J; Di Santo R; McColl DJ; Weber J; Quiñones-Mateu M
AIDS Rev; 2008; 10(3):172-89. PubMed ID: 18820719
[TBL] [Abstract][Full Text] [Related]
5. Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
Dayam R; Sanchez T; Clement O; Shoemaker R; Sei S; Neamati N
J Med Chem; 2005 Jan; 48(1):111-20. PubMed ID: 15634005
[TBL] [Abstract][Full Text] [Related]
6. A platform for designing HIV integrase inhibitors. Part 2: a two-metal binding model as a potential mechanism of HIV integrase inhibitors.
Kawasuji T; Fuji M; Yoshinaga T; Sato A; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8420-9. PubMed ID: 17005407
[TBL] [Abstract][Full Text] [Related]
7. Study on the interactions between diketo-acid inhibitors and prototype foamy virus integrase-DNA complex via molecular docking and comparative molecular dynamics simulation methods.
Hu JP; He HQ; Tang DY; Sun GF; Zhang YQ; Fan J; Chang S
J Biomol Struct Dyn; 2013; 31(7):734-47. PubMed ID: 22913375
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors.
Meadows DC; Mathews TB; North TW; Hadd MJ; Kuo CL; Neamati N; Gervay-Hague J
J Med Chem; 2005 Jul; 48(14):4526-34. PubMed ID: 15999991
[TBL] [Abstract][Full Text] [Related]
9. Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes.
Grobler JA; Stillmock K; Hu B; Witmer M; Felock P; Espeseth AS; Wolfe A; Egbertson M; Bourgeois M; Melamed J; Wai JS; Young S; Vacca J; Hazuda DJ
Proc Natl Acad Sci U S A; 2002 May; 99(10):6661-6. PubMed ID: 11997448
[TBL] [Abstract][Full Text] [Related]
10. Benzyl amide-ketoacid inhibitors of HIV-integrase.
Walker MA; Johnson T; Naidu BN; Banville J; Remillard R; Plamondon S; Martel A; Li C; Torri A; Samanta H; Lin Z; Dicker I; Krystal M; Meanwell NA
Bioorg Med Chem Lett; 2007 Sep; 17(17):4886-90. PubMed ID: 17604626
[TBL] [Abstract][Full Text] [Related]
11. Chemistry and structure-activity relationship of HIV-1 integrase inhibitor integracide B and related natural products.
Singh SB; Ondeyka JG; Schleif WA; Felock P; Hazuda DJ
J Nat Prod; 2003 Oct; 66(10):1338-44. PubMed ID: 14575434
[TBL] [Abstract][Full Text] [Related]
12. Structure-activity relationships of HIV-1 integrase inhibitors--enzyme-ligand interactions.
Maurin C; Bailly F; Cotelle P
Curr Med Chem; 2003 Sep; 10(18):1795-810. PubMed ID: 12871105
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition.
Vandurm P; Guiguen A; Cauvin C; Georges B; Le Van K; Michaux C; Cardona C; Mbemba G; Mouscadet JF; Hevesi L; Van Lint C; Wouters J
Eur J Med Chem; 2011 May; 46(5):1749-56. PubMed ID: 21385662
[TBL] [Abstract][Full Text] [Related]
14. Characterization and structural analysis of HIV-1 integrase conservation.
Ceccherini-Silberstein F; Malet I; D'Arrigo R; Antinori A; Marcelin AG; Perno CF
AIDS Rev; 2009; 11(1):17-29. PubMed ID: 19290031
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of HIV-1 integrase by small molecules: the potential for a new class of AIDS chemotherapeutics.
Young SD
Curr Opin Drug Discov Devel; 2001 Jul; 4(4):402-10. PubMed ID: 11727305
[TBL] [Abstract][Full Text] [Related]
16. A platform for designing HIV integrase inhibitors. Part 1: 2-hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores.
Kawasuji T; Yoshinaga T; Sato A; Yodo M; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8430-45. PubMed ID: 17010623
[TBL] [Abstract][Full Text] [Related]
17. Dissecting Tn5 transposition using HIV-1 integrase diketoacid inhibitors.
Czyz A; Stillmock KA; Hazuda DJ; Reznikoff WS
Biochemistry; 2007 Sep; 46(38):10776-89. PubMed ID: 17725323
[TBL] [Abstract][Full Text] [Related]
18. Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase.
Verschueren WG; Dierynck I; Amssoms KI; Hu L; Boonants PM; Pille GM; Daeyaert FF; Hertogs K; Surleraux DL; Wigerinck PB
J Med Chem; 2005 Mar; 48(6):1930-40. PubMed ID: 15771437
[TBL] [Abstract][Full Text] [Related]
19. The integrase of the human immunodeficiency virus as a novel target for the antiviral therapy of AIDS.
Witvrouw M; Debyser Z
Verh K Acad Geneeskd Belg; 2003; 65(5):325-34. PubMed ID: 14671848
[TBL] [Abstract][Full Text] [Related]
20. Dicaffeoylquinic acid inhibitors of human immunodeficiency virus integrase: inhibition of the core catalytic domain of human immunodeficiency virus integrase.
Robinson WE; Cordeiro M; Abdel-Malek S; Jia Q; Chow SA; Reinecke MG; Mitchell WM
Mol Pharmacol; 1996 Oct; 50(4):846-55. PubMed ID: 8863829
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
