339 related articles for article (PubMed ID: 11989648)
1. Carcinogenic and nephrotoxic alkaloids aristolochic acids upon activation by NADPH : cytochrome P450 reductase form adducts found in DNA of patients with Chinese herbs nephropathy.
Stiborová M; Hájek M; Frei E; Schmeiser HH
Gen Physiol Biophys; 2001 Dec; 20(4):375-92. PubMed ID: 11989648
[TBL] [Abstract][Full Text] [Related]
2. Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase -- (32)P-postlabeling analysis of DNA adduct formation.
Stiborová M; Frei E; Breuer A; Wiessler M; Schmeiser HH
Mutat Res; 2001 Jun; 493(1-2):149-60. PubMed ID: 11516724
[TBL] [Abstract][Full Text] [Related]
3. Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.
Stiborová M; Frei E; Hodek P; Wiessler M; Schmeiser HH
Int J Cancer; 2005 Jan; 113(2):189-97. PubMed ID: 15386410
[TBL] [Abstract][Full Text] [Related]
4. Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy.
Stiborová M; Frei E; Sopko B; Wiessler M; Schmeiser HH
Carcinogenesis; 2002 Apr; 23(4):617-25. PubMed ID: 11960915
[TBL] [Abstract][Full Text] [Related]
5. 32P-post-labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy.
Bieler CA; Stiborova M; Wiessler M; Cosyns JP; van Ypersele de Strihou C; Schmeiser HH
Carcinogenesis; 1997 May; 18(5):1063-7. PubMed ID: 9163697
[TBL] [Abstract][Full Text] [Related]
6. Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy.
Stiborová M; Frei E; Breuer A; Bieler CA; Schmeiser HH
Exp Toxicol Pathol; 1999 Jul; 51(4-5):421-7. PubMed ID: 10445409
[TBL] [Abstract][Full Text] [Related]
7. Human enzymes involved in the metabolic activation of carcinogenic aristolochic acids: evidence for reductive activation by cytochromes P450 1A1 and 1A2.
Stiborová M; Frei E; Wiessler M; Schmeiser HH
Chem Res Toxicol; 2001 Aug; 14(8):1128-37. PubMed ID: 11511187
[TBL] [Abstract][Full Text] [Related]
8. Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.
Stiborová M; Frei E; Sopko B; Sopková K; Marková V; Lanková M; Kumstýrová T; Wiessler M; Schmeiser HH
Carcinogenesis; 2003 Oct; 24(10):1695-703. PubMed ID: 12869422
[TBL] [Abstract][Full Text] [Related]
9. The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen.
Stiborová M; Sopko B; Hodek P; Frei E; Schmeiser HH; Hudecek J
Cancer Lett; 2005 Nov; 229(2):193-204. PubMed ID: 16125300
[TBL] [Abstract][Full Text] [Related]
10. Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy.
Stiborová M; Frei E; Arlt VM; Schmeiser HH
Mutat Res; 2008; 658(1-2):55-67. PubMed ID: 17851120
[TBL] [Abstract][Full Text] [Related]
11. Characterization of DNA adducts formed by aristolochic acids in the target organ (forestomach) of rats by 32P-postlabelling analysis using different chromatographic procedures.
Stiborová M; Fernando RC; Schmeiser HH; Frei E; Pfau W; Wiessler M
Carcinogenesis; 1994 Jun; 15(6):1187-92. PubMed ID: 8020154
[TBL] [Abstract][Full Text] [Related]
12. The role of biotransformation enzymes in the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions and difficult answers.
Stiborova M; Frei E; Arlt VM; Schmeiser HH
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub; 2009 Mar; 153(1):5-11. PubMed ID: 19365519
[TBL] [Abstract][Full Text] [Related]
13. Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver.
Stiborova M; Mares J; Levova K; Pavlickova J; Barta F; Hodek P; Frei E; Schmeiser HH
Neuro Endocrinol Lett; 2011; 32 Suppl 1():121-30. PubMed ID: 22167220
[TBL] [Abstract][Full Text] [Related]
14. Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.
Arlt VM; Stiborova M; Hewer A; Schmeiser HH; Phillips DH
Cancer Res; 2003 Jun; 63(11):2752-61. PubMed ID: 12782579
[TBL] [Abstract][Full Text] [Related]
15. Detection of DNA adducts formed by aristolochic acid in renal tissue from patients with Chinese herbs nephropathy.
Schmeiser HH; Bieler CA; Wiessler M; van Ypersele de Strihou C; Cosyns JP
Cancer Res; 1996 May; 56(9):2025-8. PubMed ID: 8616845
[TBL] [Abstract][Full Text] [Related]
16. Comparison of DNA adduct formation by aristolochic acids in various in vitro activation systems by 32P-post-labelling: evidence for reductive activation by peroxidases.
Schmeiser HH; Frei E; Wiessler M; Stiborova M
Carcinogenesis; 1997 May; 18(5):1055-62. PubMed ID: 9163696
[TBL] [Abstract][Full Text] [Related]
17. Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.
Levová K; Moserová M; Kotrbová V; Sulc M; Henderson CJ; Wolf CR; Phillips DH; Frei E; Schmeiser HH; Mares J; Arlt VM; Stiborová M
Toxicol Sci; 2011 May; 121(1):43-56. PubMed ID: 21362632
[TBL] [Abstract][Full Text] [Related]
18. Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases.
Martinek V; Kubickova B; Arlt VM; Frei E; Schmeiser HH; Hudecek J; Stiborova M
Neuro Endocrinol Lett; 2011; 32 Suppl 1():57-70. PubMed ID: 22167209
[TBL] [Abstract][Full Text] [Related]
19. Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/polyacrylamide gel electrophoresis analysis.
Dong H; Suzuki N; Torres MC; Bonala RR; Johnson F; Grollman AP; Shibutani S
Drug Metab Dispos; 2006 Jul; 34(7):1122-7. PubMed ID: 16611860
[TBL] [Abstract][Full Text] [Related]
20. Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes.
Stiborova M; Cechova T; Borek-Dohalska L; Moserova M; Frei E; Schmeiser HH; Paca J; Arlt VM
Neuro Endocrinol Lett; 2012; 33 Suppl 3():8-15. PubMed ID: 23353838
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
