BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

409 related articles for article (PubMed ID: 11991805)

  • 1. Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.
    Chanas SA; Jiang Q; McMahon M; McWalter GK; McLellan LI; Elcombe CR; Henderson CJ; Wolf CR; Moffat GJ; Itoh K; Yamamoto M; Hayes JD
    Biochem J; 2002 Jul; 365(Pt 2):405-16. PubMed ID: 11991805
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
    McMahon M; Itoh K; Yamamoto M; Chanas SA; Henderson CJ; McLellan LI; Wolf CR; Cavin C; Hayes JD
    Cancer Res; 2001 Apr; 61(8):3299-307. PubMed ID: 11309284
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of mouse Pi-class glutathione S-transferase gene by Nrf2(NF-E2-related factor 2) and androgen.
    Ikeda H; Serria MS; Kakizaki I; Hatayama I; Satoh K; Tsuchida S; Muramatsu M; Nishi S; Sakai M
    Biochem J; 2002 Jun; 364(Pt 2):563-70. PubMed ID: 12023900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene.
    Vollrath V; Wielandt AM; Iruretagoyena M; Chianale J
    Biochem J; 2006 May; 395(3):599-609. PubMed ID: 16426233
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
    Kwak MK; Itoh K; Yamamoto M; Sutter TR; Kensler TW
    Mol Med; 2001 Feb; 7(2):135-45. PubMed ID: 11471548
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells.
    Satoh K; Itoh K; Yamamoto M; Tanaka M; Hayakari M; Ookawa K; Yamazaki T; Sato T; Tsuchida S; Hatayama I
    Carcinogenesis; 2002 Mar; 23(3):457-62. PubMed ID: 11895860
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin.
    Hayes JD; Chanas SA; Henderson CJ; McMahon M; Sun C; Moffat GJ; Wolf CR; Yamamoto M
    Biochem Soc Trans; 2000 Feb; 28(2):33-41. PubMed ID: 10816095
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates.
    McWalter GK; Higgins LG; McLellan LI; Henderson CJ; Song L; Thornalley PJ; Itoh K; Yamamoto M; Hayes JD
    J Nutr; 2004 Dec; 134(12 Suppl):3499S-3506S. PubMed ID: 15570060
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARĪ±-, and Nrf2-null mice.
    Aleksunes LM; Klaassen CD
    Drug Metab Dispos; 2012 Jul; 40(7):1366-79. PubMed ID: 22496397
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein.
    Higgins LG; Cavin C; Itoh K; Yamamoto M; Hayes JD
    Toxicol Appl Pharmacol; 2008 Feb; 226(3):328-37. PubMed ID: 18028974
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
    Ramos-Gomez M; Kwak MK; Dolan PM; Itoh K; Yamamoto M; Talalay P; Kensler TW
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3410-5. PubMed ID: 11248092
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
    Itoh K; Chiba T; Takahashi S; Ishii T; Igarashi K; Katoh Y; Oyake T; Hayashi N; Satoh K; Hatayama I; Yamamoto M; Nabeshima Y
    Biochem Biophys Res Commun; 1997 Jul; 236(2):313-22. PubMed ID: 9240432
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of hepatitis B virus X repression of C/EBPbeta activity in the down-regulation of glutathione S-transferase A2 gene: implications in other phase II detoxifying enzyme expression.
    Cho IJ; Ki SH; Brooks C; Kim SG
    Xenobiotica; 2009 Feb; 39(2):182-92. PubMed ID: 19255944
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of mouse glutathione S-transferases by chemoprotectors. Molecular evidence for the existence of three distinct alpha-class glutathione S-transferase subunits, Ya1, Ya2, and Ya3, in mouse liver.
    McLellan LI; Kerr LA; Cronshaw AD; Hayes JD
    Biochem J; 1991 Jun; 276 ( Pt 2)(Pt 2):461-9. PubMed ID: 2049074
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemical inducers of rodent glutathione s-transferases down-regulate human GSTA1 transcription through a mechanism involving variant hepatic nuclear factor 1-C.
    Romero L; Ng L; Kirby GM
    Mol Pharmacol; 2006 Jul; 70(1):277-86. PubMed ID: 16608922
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element.
    Jowsey IR; Jiang Q; Itoh K; Yamamoto M; Hayes JD
    Mol Pharmacol; 2003 Nov; 64(5):1018-28. PubMed ID: 14573750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.
    Suh JH; Shenvi SV; Dixon BM; Liu H; Jaiswal AK; Liu RM; Hagen TM
    Proc Natl Acad Sci U S A; 2004 Mar; 101(10):3381-6. PubMed ID: 14985508
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ceramide, an apoptotic rheostat, inhibits CCAAT/enhancer binding protein-beta and NF-E2-related factor-2 activation: the role in glutathione S-transferase A2 gene repression.
    Park IN; Cho IJ; Kim SG
    Drug Metab Dispos; 2004 Sep; 32(9):893-7. PubMed ID: 15319326
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A basis for differentiating among the multiple human Mu-glutathione S-transferases and molecular cloning of brain GSTM5.
    Takahashi Y; Campbell EA; Hirata Y; Takayama T; Listowsky I
    J Biol Chem; 1993 Apr; 268(12):8893-8. PubMed ID: 8473333
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Complementary DNA cloning, messenger RNA expression, and induction of alpha-class glutathione S-transferases in mouse tissues.
    Buetler TM; Eaton DL
    Cancer Res; 1992 Jan; 52(2):314-8. PubMed ID: 1728405
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.