BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 12006525)

  • 1. Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival.
    Ermoian RP; Furniss CS; Lamborn KR; Basila D; Berger MS; Gottschalk AR; Nicholas MK; Stokoe D; Haas-Kogan DA
    Clin Cancer Res; 2002 May; 8(5):1100-6. PubMed ID: 12006525
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib.
    Haas-Kogan DA; Prados MD; Tihan T; Eberhard DA; Jelluma N; Arvold ND; Baumber R; Lamborn KR; Kapadia A; Malec M; Berger MS; Stokoe D
    J Natl Cancer Inst; 2005 Jun; 97(12):880-7. PubMed ID: 15956649
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dysregulated PTEN-PKB and negative receptor status in human breast cancer.
    Shi W; Zhang X; Pintilie M; Ma N; Miller N; Banerjee D; Tsao MS; Mak T; Fyles A; Liu FF
    Int J Cancer; 2003 Mar; 104(2):195-203. PubMed ID: 12569575
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways.
    Liu W; Asa SL; Fantus IG; Walfish PG; Ezzat S
    Am J Pathol; 2002 Feb; 160(2):511-9. PubMed ID: 11839571
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells.
    Taylor V; Wong M; Brandts C; Reilly L; Dean NM; Cowsert LM; Moodie S; Stokoe D
    Mol Cell Biol; 2000 Sep; 20(18):6860-71. PubMed ID: 10958682
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.
    Edwards LA; Thiessen B; Dragowska WH; Daynard T; Bally MB; Dedhar S
    Oncogene; 2005 May; 24(22):3596-605. PubMed ID: 15782140
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhanced protein kinase B/Akt signalling in pituitary tumours.
    Musat M; Korbonits M; Kola B; Borboli N; Hanson MR; Nanzer AM; Grigson J; Jordan S; Morris DG; Gueorguiev M; Coculescu M; Basu S; Grossman AB
    Endocr Relat Cancer; 2005 Jun; 12(2):423-33. PubMed ID: 15947113
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells.
    Li DM; Sun H
    Proc Natl Acad Sci U S A; 1998 Dec; 95(26):15406-11. PubMed ID: 9860981
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.
    Nakamura JL; Karlsson A; Arvold ND; Gottschalk AR; Pieper RO; Stokoe D; Haas-Kogan DA
    J Neurooncol; 2005 Feb; 71(3):215-22. PubMed ID: 15735908
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.
    Wick W; Furnari FB; Naumann U; Cavenee WK; Weller M
    Oncogene; 1999 Jul; 18(27):3936-43. PubMed ID: 10435616
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis.
    Gomez-Manzano C; Fueyo J; Jiang H; Glass TL; Lee HY; Hu M; Liu JL; Jasti SL; Liu TJ; Conrad CA; Yung WK
    Ann Neurol; 2003 Jan; 53(1):109-17. PubMed ID: 12509854
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biochemical differences between SUDHL-1 and KARPAS 299 cells derived from t(2;5)-positive anaplastic large cell lymphoma are responsible for the different sensitivity to the antiproliferative effect of p27(Kip1).
    Turturro F; Frist AY; Arnold MD; Seth P; Pulford K
    Oncogene; 2001 Jul; 20(33):4466-75. PubMed ID: 11494142
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localization.
    Motti ML; Califano D; Troncone G; De Marco C; Migliaccio I; Palmieri E; Pezzullo L; Palombini L; Fusco A; Viglietto G
    Am J Pathol; 2005 Mar; 166(3):737-49. PubMed ID: 15743786
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1.
    Bruni P; Boccia A; Baldassarre G; Trapasso F; Santoro M; Chiappetta G; Fusco A; Viglietto G
    Oncogene; 2000 Jun; 19(28):3146-55. PubMed ID: 10918569
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.
    Kurose K; Zhou XP; Araki T; Cannistra SA; Maher ER; Eng C
    Am J Pathol; 2001 Jun; 158(6):2097-106. PubMed ID: 11395387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression?
    Hlobilkova A; Ehrmann J; Sedlakova E; Krejci V; Knizetova P; Fiuraskova M; Kala M; Kalita O; Kolar Z
    Neoplasma; 2007; 54(4):334-41. PubMed ID: 17822324
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammalian target of rapamycin signaling pathway contributes to glioma progression and patients' prognosis.
    Yang J; Liao D; Wang Z; Liu F; Wu G
    J Surg Res; 2011 Jun; 168(1):97-102. PubMed ID: 20036387
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PTEN induces G(1) cell cycle arrest and decreases cyclin D3 levels in endometrial carcinoma cells.
    Zhu X; Kwon CH; Schlosshauer PW; Ellenson LH; Baker SJ
    Cancer Res; 2001 Jun; 61(11):4569-75. PubMed ID: 11389092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
    Shin I; Yakes FM; Rojo F; Shin NY; Bakin AV; Baselga J; Arteaga CL
    Nat Med; 2002 Oct; 8(10):1145-52. PubMed ID: 12244301
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The expression of PAX6, PTEN, vascular endothelial growth factor, and epidermal growth factor receptor in gliomas: relationship to tumor grade and survival.
    Zhou YH; Tan F; Hess KR; Yung WK
    Clin Cancer Res; 2003 Aug; 9(9):3369-75. PubMed ID: 12960124
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.