109 related articles for article (PubMed ID: 12007434)
1. MAP kinase module: the Ksr connection.
Roy F; Therrien M
Curr Biol; 2002 Apr; 12(9):R325-7. PubMed ID: 12007434
[TBL] [Abstract][Full Text] [Related]
2. Murine Ksr interacts with MEK and inhibits Ras-induced transformation.
Denouel-Galy A; Douville EM; Warne PH; Papin C; Laugier D; Calothy G; Downward J; Eychène A
Curr Biol; 1998 Jan; 8(1):46-55. PubMed ID: 9427625
[TBL] [Abstract][Full Text] [Related]
3. C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1.
Müller J; Ory S; Copeland T; Piwnica-Worms H; Morrison DK
Mol Cell; 2001 Nov; 8(5):983-93. PubMed ID: 11741534
[TBL] [Abstract][Full Text] [Related]
4. Kinase suppressor of ras is necessary for tumor necrosis factor alpha activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in intestinal epithelial cells.
Yan F; Polk DB
Cancer Res; 2001 Feb; 61(3):963-9. PubMed ID: 11221891
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation of raf-1 by kinase suppressor of ras is inhibited by "MEK-specific" inhibitors PD 098059 and U0126 in differentiating HL60 cells.
Wang X; Studzinski GP
Exp Cell Res; 2001 Aug; 268(2):294-300. PubMed ID: 11478855
[TBL] [Abstract][Full Text] [Related]
6. The Raf/MEK/ERK pathway: new concepts of activation.
Peyssonnaux C; Eychène A
Biol Cell; 2001 Sep; 93(1-2):53-62. PubMed ID: 11730323
[TBL] [Abstract][Full Text] [Related]
7. Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.
Stewart S; Sundaram M; Zhang Y; Lee J; Han M; Guan KL
Mol Cell Biol; 1999 Aug; 19(8):5523-34. PubMed ID: 10409742
[TBL] [Abstract][Full Text] [Related]
8. KSR modulates signal propagation within the MAPK cascade.
Therrien M; Michaud NR; Rubin GM; Morrison DK
Genes Dev; 1996 Nov; 10(21):2684-95. PubMed ID: 8946910
[TBL] [Abstract][Full Text] [Related]
9. Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.
Yu W; Fantl WJ; Harrowe G; Williams LT
Curr Biol; 1998 Jan; 8(1):56-64. PubMed ID: 9427629
[TBL] [Abstract][Full Text] [Related]
10. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
[TBL] [Abstract][Full Text] [Related]
11. The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation.
Sugimoto T; Stewart S; Han M; Guan KL
EMBO J; 1998 Mar; 17(6):1717-27. PubMed ID: 9501093
[TBL] [Abstract][Full Text] [Related]
12. Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells.
Lefevre G; Calipel A; Mouriaux F; Hecquet C; Malecaze F; Mascarelli F
Oncogene; 2003 Dec; 22(55):8813-22. PubMed ID: 14654778
[TBL] [Abstract][Full Text] [Related]
13. MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity.
Gardner AM; Vaillancourt RR; Lange-Carter CA; Johnson GL
Mol Biol Cell; 1994 Feb; 5(2):193-201. PubMed ID: 8019005
[TBL] [Abstract][Full Text] [Related]
14. Dominant negative mutants of mitogen-activated protein kinase pathway.
Arboleda MJ; Eberwein D; Hibner B; Lyons JF
Methods Enzymol; 2001; 332():353-67. PubMed ID: 11305110
[No Abstract] [Full Text] [Related]
15. Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo.
Nguyen A; Burack WR; Stock JL; Kortum R; Chaika OV; Afkarian M; Muller WJ; Murphy KM; Morrison DK; Lewis RE; McNeish J; Shaw AS
Mol Cell Biol; 2002 May; 22(9):3035-45. PubMed ID: 11940661
[TBL] [Abstract][Full Text] [Related]
16. MEK drives BRAF activation through allosteric control of KSR proteins.
Lavoie H; Sahmi M; Maisonneuve P; Marullo SA; Thevakumaran N; Jin T; Kurinov I; Sicheri F; Therrien M
Nature; 2018 Feb; 554(7693):549-553. PubMed ID: 29433126
[TBL] [Abstract][Full Text] [Related]
17. The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia.
Lee JT; McCubrey JA
Leukemia; 2002 Apr; 16(4):486-507. PubMed ID: 11960326
[TBL] [Abstract][Full Text] [Related]
18. Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase.
Salmeron A; Ahmad TB; Carlile GW; Pappin D; Narsimhan RP; Ley SC
EMBO J; 1996 Feb; 15(4):817-26. PubMed ID: 8631303
[TBL] [Abstract][Full Text] [Related]
19. Raf revealed in life-or-death decisions.
Pritchard C; McMahon M
Nat Genet; 1997 Jul; 16(3):214-5. PubMed ID: 9207779
[No Abstract] [Full Text] [Related]
20. Critical contribution of linker proteins to Raf kinase activation.
Anselmo AN; Bumeister R; Thomas JM; White MA
J Biol Chem; 2002 Feb; 277(8):5940-3. PubMed ID: 11741918
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
