223 related articles for article (PubMed ID: 12008205)
1. BNP7787, a novel protector against platinum-related toxicities, does not affect the efficacy of cisplatin or carboplatin in human tumour xenografts.
Boven E; Verschraagen M; Hulscher TM; Erkelens CA; Hausheer FH; Pinedo HM; van der Vijgh WJ
Eur J Cancer; 2002 May; 38(8):1148-56. PubMed ID: 12008205
[TBL] [Abstract][Full Text] [Related]
2. Pharmacokinetic behaviour of the chemoprotectants BNP7787 and mesna after an i.v. bolus injection in rats.
Verschraagen M; Boven E; Torun E; Erkelens CA; Hausheer FH; van der Vijgh WJ
Br J Cancer; 2004 Apr; 90(8):1654-9. PubMed ID: 15083199
[TBL] [Abstract][Full Text] [Related]
3. Possible (enzymatic) routes and biological sites for metabolic reduction of BNP7787, a new protector against cisplatin-induced side-effects.
Verschraagen M; Boven E; Torun E; Hausheer FH; Bast A; van der Vijgh WJ
Biochem Pharmacol; 2004 Aug; 68(3):493-502. PubMed ID: 15242815
[TBL] [Abstract][Full Text] [Related]
4. Pharmacokinetics and preliminary clinical data of the novel chemoprotectant BNP7787 and cisplatin and their metabolites.
Verschraagen M; Boven E; Ruijter R; van der Born K; Berkhof J; Hausheer FH; van der Vijgh WJ
Clin Pharmacol Ther; 2003 Aug; 74(2):157-69. PubMed ID: 12891226
[TBL] [Abstract][Full Text] [Related]
5. Pharmacokinetics of BNP7787 and its metabolite mesna in plasma and ascites: a case report.
Verschraagen M; Boven E; Zegers I; Hausheer FH; Van der Vijgh WJ
Cancer Chemother Pharmacol; 2003 Jun; 51(6):525-9. PubMed ID: 12750838
[TBL] [Abstract][Full Text] [Related]
6. Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of gamma-glutamyl transpeptidase.
Hausheer FH; Shanmugarajah D; Leverett BD; Chen X; Huang Q; Kochat H; Petluru PN; Parker AR
Cancer Chemother Pharmacol; 2010 Apr; 65(5):941-51. PubMed ID: 19714332
[TBL] [Abstract][Full Text] [Related]
7. BNP7787-mediated modulation of paclitaxel- and cisplatin-induced aberrant microtubule protein polymerization in vitro.
Parker AR; Petluru PN; Wu M; Zhao M; Kochat H; Hausheer FH
Mol Cancer Ther; 2010 Sep; 9(9):2558-67. PubMed ID: 20807779
[TBL] [Abstract][Full Text] [Related]
8. Pharmacokinetics of cisplatin with and without amifostine in tumour-bearing nude mice.
Korst AE; Boven E; van der Sterre ML; Fichtinger-Schepman AM; van der Vijgh WJ
Eur J Cancer; 1998 Feb; 34(3):412-6. PubMed ID: 9640232
[TBL] [Abstract][Full Text] [Related]
9. Modulation of plasma thiols and mixed disulfides by BNP7787 in patients receiving paclitaxel/cisplatin therapy.
Pendyala L; Schwartz G; Smith P; Zdanowicz J; Murphy M; Hausheer F
Cancer Chemother Pharmacol; 2003 May; 51(5):376-84. PubMed ID: 12682786
[TBL] [Abstract][Full Text] [Related]
10. Phase I and pharmacologic study of BNP7787, a novel chemoprotector in patients with advanced non-small cell lung cancer.
Masuda N; Negoro S; Hausheer F; Nakagawa K; Matsui K; Kudoh S; Takeda K; Yamamoto N; Yoshimura N; Ohashi Y; Fukuoka M
Cancer Chemother Pharmacol; 2011 Mar; 67(3):533-42. PubMed ID: 20473611
[TBL] [Abstract][Full Text] [Related]
11. Influence of single and multiple doses of amifostine on the efficacy and the pharmacokinetics of carboplatin in mice.
Korst AE; Boven E; van der Sterre ML; Fichtinger-Schepman AM; van der Vijgh WJ
Br J Cancer; 1997; 75(10):1439-46. PubMed ID: 9166935
[TBL] [Abstract][Full Text] [Related]
12. Amifostine (Ethyol): pharmacokinetic and pharmacodynamic effects in vivo.
van der Vijgh WJ; Korst AE
Eur J Cancer; 1996; 32A Suppl 4():S26-30. PubMed ID: 8976819
[TBL] [Abstract][Full Text] [Related]
13. Phase I and pharmacokinetic study of the novel chemoprotector BNP7787 in combination with cisplatin and attempt to eliminate the hydration schedule.
Boven E; Westerman M; van Groeningen CJ; Verschraagen M; Ruijter R; Zegers I; van der Vijgh WJ; Giaccone G
Br J Cancer; 2005 May; 92(9):1636-43. PubMed ID: 15841080
[TBL] [Abstract][Full Text] [Related]
14. Modulation of platinum-induced toxicities and therapeutic index: mechanistic insights and first- and second-generation protecting agents.
Hausheer FH; Kanter P; Cao S; Haridas K; Seetharamulu P; Reddy D; Petluru P; Zhao M; Murali D; Saxe JD; Yao S; Martinez N; Zukowski A; Rustum YM
Semin Oncol; 1998 Oct; 25(5):584-99. PubMed ID: 9783598
[TBL] [Abstract][Full Text] [Related]
15. The chemical reactivity of BNP7787 and its metabolite mesna with the cytostatic agent cisplatin: comparison with the nucleophiles thiosulfate, DDTC, glutathione and its disulfide GSSG.
Verschraagen M; Kedde MA; Hausheer FH; Van Der Vijgh WJ
Cancer Chemother Pharmacol; 2003 Jun; 51(6):499-504. PubMed ID: 12715205
[TBL] [Abstract][Full Text] [Related]
16. cis-Amminedichloro(2-methylpyridine) platinum(II) (AMD473), a novel sterically hindered platinum complex: in vivo activity, toxicology, and pharmacokinetics in mice.
Raynaud FI; Boxall FE; Goddard PM; Valenti M; Jones M; Murrer BA; Abrams M; Kelland LR
Clin Cancer Res; 1997 Nov; 3(11):2063-74. PubMed ID: 9815598
[TBL] [Abstract][Full Text] [Related]
17. Simultaneous determination of BNP7787 and its metabolite mesna in plasma and tissue by micro-HPLC with a dual electrochemical detector.
Verschraagen M; Zwiers TH; Torun E; Donker MG; Reinhoud NJ; Van der Vijgh WJ
J Pharm Sci; 2003 May; 92(5):1040-50. PubMed ID: 12712424
[TBL] [Abstract][Full Text] [Related]
18. Quantification of BNP7787 (dimesna) and its metabolite mesna in human plasma and urine by high-performance liquid chromatography with electrochemical detection.
Verschraagen M; Zwiers TH; de Koning PE; Welink J; van der Vijgh WJ
J Chromatogr B Biomed Sci Appl; 2001 Apr; 753(2):293-302. PubMed ID: 11334343
[TBL] [Abstract][Full Text] [Related]
19. Accumulation of BNP7787 in human renal proximal tubule cells.
Hausheer FH; Ding D; Shanmugarajah D; Leverett BD; Huang Q; Chen X; Kochat H; Ayala PY; Petluru PN; Parker AR
J Pharm Sci; 2011 Sep; 100(9):3977-84. PubMed ID: 21344411
[TBL] [Abstract][Full Text] [Related]
20. Influence of mesna on the pharmacokinetics of cisplatin and carboplatin in pediatric cancer patients.
Kangarloo SB; Gangopadhyay SB; Syme RM; Wolff JE; Glück S
Med Oncol; 2004; 21(1):9-20. PubMed ID: 15034209
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
