BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 12011990)

  • 21. A P53-dependent, telomere-independent proliferative life span barrier in human astrocytes consistent with the molecular genetics of glioma development.
    Evans RJ; Wyllie FS; Wynford-Thomas D; Kipling D; Jones CJ
    Cancer Res; 2003 Aug; 63(16):4854-61. PubMed ID: 12941806
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Fibroblast clones from patients with Hutchinson-Gilford progeria can senesce despite the presence of telomerase.
    Wallis CV; Sheerin AN; Green MH; Jones CJ; Kipling D; Faragher RG
    Exp Gerontol; 2004 Apr; 39(4):461-7. PubMed ID: 15050279
    [TBL] [Abstract][Full Text] [Related]  

  • 23. hTERT associates with human telomeres and enhances genomic stability and DNA repair.
    Sharma GG; Gupta A; Wang H; Scherthan H; Dhar S; Gandhi V; Iliakis G; Shay JW; Young CS; Pandita TK
    Oncogene; 2003 Jan; 22(1):131-46. PubMed ID: 12527915
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Telomerase-immortalized sheep fibroblasts can be reprogrammed by nuclear transfer to undergo early development.
    Cui W; Wylie D; Aslam S; Dinnyes A; King T; Wilmut I; Clark AJ
    Biol Reprod; 2003 Jul; 69(1):15-21. PubMed ID: 12606403
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres.
    Munro J; Steeghs K; Morrison V; Ireland H; Parkinson EK
    Oncogene; 2001 Jun; 20(27):3541-52. PubMed ID: 11429701
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Telomerase activity level, but not hTERT mRNA and hTR level, regulates telomere length in telomerase-reconstituted primary fibroblasts.
    Swiggers SJ; Nibbeling HA; Zeilemaker A; Kuijpers MA; Mattern KA; Zijlmans JM
    Exp Cell Res; 2004 Jul; 297(2):434-43. PubMed ID: 15212946
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Reconstitution of active telomerase in primary human foreskin fibroblasts: effects on proliferative characteristics and response to ionizing radiation.
    Kampinga HH; Van Waarde-Verhagen MA; Van Assen-Bolt AJ; Nieuwenhuis B; Rodemann HP; Prowse KR; Linskens MH
    Int J Radiat Biol; 2004 May; 80(5):377-88. PubMed ID: 15223771
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Use of telomerase to create bioengineered tissues.
    Shay JW; Wright WE
    Ann N Y Acad Sci; 2005 Dec; 1057():479-91. PubMed ID: 16399914
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts.
    Yudoh K; Matsuno H; Nakazawa F; Katayama R; Kimura T
    J Bone Miner Res; 2001 Aug; 16(8):1453-64. PubMed ID: 11499868
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells.
    Misawa M; Tauchi T; Sashida G; Nakajima A; Abe K; Ohyashiki JH; Ohyashiki K
    Int J Oncol; 2002 Nov; 21(5):1087-92. PubMed ID: 12370759
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras.
    MacKenzie KL; Franco S; Naiyer AJ; May C; Sadelain M; Rafii S; Moore MA
    Oncogene; 2002 Jun; 21(27):4200-11. PubMed ID: 12082607
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Replicative senescence in sheep fibroblasts is a p53 dependent process.
    Davis T; Skinner JW; Faragher RG; Jones CJ; Kipling D
    Exp Gerontol; 2005; 40(1-2):17-26. PubMed ID: 15664728
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells.
    Goldkorn A; Blackburn EH
    Cancer Res; 2006 Jun; 66(11):5763-71. PubMed ID: 16740715
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Telomerase activity does not always imply telomere maintenance.
    Ouellette MM; Aisner DL; Savre-Train I; Wright WE; Shay JW
    Biochem Biophys Res Commun; 1999 Jan; 254(3):795-803. PubMed ID: 9920820
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts.
    Noble JR; Zhong ZH; Neumann AA; Melki JR; Clark SJ; Reddel RR
    Oncogene; 2004 Apr; 23(17):3116-21. PubMed ID: 14743210
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters.
    Atkinson SP; Hoare SF; Glasspool RM; Keith WN
    Cancer Res; 2005 Sep; 65(17):7585-90. PubMed ID: 16140922
    [TBL] [Abstract][Full Text] [Related]  

  • 37. hTERT antagonizes p53-induced apoptosis independently of telomerase activity.
    Rahman R; Latonen L; Wiman KG
    Oncogene; 2005 Feb; 24(8):1320-7. PubMed ID: 15608686
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis.
    Lee MK; Hande MP; Sabapathy K
    J Cell Sci; 2005 Feb; 118(Pt 4):819-29. PubMed ID: 15687103
    [TBL] [Abstract][Full Text] [Related]  

  • 39. [Inhibition of anti-sense human telomerase reverse transcriptase (hTERT) retroviral vector on lung cancer cells].
    Tian FJ; Wang ZY; Ma JY; Zhao YX; Lu W
    Ai Zheng; 2004 May; 23(5):545-9. PubMed ID: 15142451
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Telomere dysfunction and telomerase reactivation in human leukemia cell lines after telomerase inhibition by the expression of a dominant-negative hTERT mutant.
    Delhommeau F; Thierry A; Feneux D; Lauret E; Leclercq E; Courtier MH; Sainteny F; Vainchenker W; Bennaceur-Griscelli A
    Oncogene; 2002 Nov; 21(54):8262-71. PubMed ID: 12447689
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.