273 related articles for article (PubMed ID: 12014635)
1. Increased expression of heat shock protein 70 in adherent ovarian cancer and mesothelioma following treatment with manumycin, a farnesyl transferase inhibitor.
Hu W; Wu W; Yeung SC; Freedman RS; Kavanagh JJ; Verschraegen CF
Anticancer Res; 2002; 22(2A):665-72. PubMed ID: 12014635
[TBL] [Abstract][Full Text] [Related]
2. Proteomic identification of heat shock protein 70 as a candidate target for enhancing apoptosis induced by farnesyl transferase inhibitor.
Hu W; Wu W; Verschraegen CF; Chen L; Mao L; Yeung SC; Kudelka AP; Freedman RS; Kavanagh JJ
Proteomics; 2003 Oct; 3(10):1904-11. PubMed ID: 14625852
[TBL] [Abstract][Full Text] [Related]
3. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
Lobell RB; Omer CA; Abrams MT; Bhimnathwala HG; Brucker MJ; Buser CA; Davide JP; deSolms SJ; Dinsmore CJ; Ellis-Hutchings MS; Kral AM; Liu D; Lumma WC; Machotka SV; Rands E; Williams TM; Graham SL; Hartman GD; Oliff AI; Heimbrook DC; Kohl NE
Cancer Res; 2001 Dec; 61(24):8758-68. PubMed ID: 11751396
[TBL] [Abstract][Full Text] [Related]
4. [Correlation between inhibitory effect of Manumycin on human hepatoma cancer cell HepG2 and Ras signal transduction pathway].
Zhou JM; Pan QC; Yang XP; Liu ZC; Liao DF; Fu LW; Liang YJ
Ai Zheng; 2002 Apr; 21(4):364-8. PubMed ID: 12452012
[TBL] [Abstract][Full Text] [Related]
5. Manumycin A, inhibitor of ras farnesyltransferase, inhibits proliferation and migration of rat vascular smooth muscle cells.
Kouchi H; Nakamura K; Fushimi K; Sakaguchi M; Miyazaki M; Ohe T; Namba M
Biochem Biophys Res Commun; 1999 Nov; 264(3):915-20. PubMed ID: 10544030
[TBL] [Abstract][Full Text] [Related]
6. Manumycin inhibits cell proliferation and the Ras signal transduction pathway in human hepatocellular carcinoma cells.
Zhou JM; Zhu XF; Pan QC; Liao DF; Li ZM; Liu ZC
Int J Mol Med; 2003 Jun; 11(6):767-71. PubMed ID: 12736720
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of growth and invasive activity of human pancreatic cancer cells by a farnesyltransferase inhibitor, manumycin.
Kainuma O; Asano T; Hasegawa M; Kenmochi T; Nakagohri T; Tokoro Y; Isono K
Pancreas; 1997 Nov; 15(4):379-83. PubMed ID: 9361092
[TBL] [Abstract][Full Text] [Related]
8. Farnesyltransferase inhibitors and human malignant pleural mesothelioma: a first-step comparative translational study.
Cesario A; Catassi A; Festi L; Imperatori A; Pericelli A; Galetta D; Margaritora S; Porziella V; Cardaci V; Granone P; Dominioni L; Russo P
Clin Cancer Res; 2005 Mar; 11(5):2026-37. PubMed ID: 15756029
[TBL] [Abstract][Full Text] [Related]
9. Manumycin inhibits farnesyltransferase and induces apoptosis of drug-resistant interleukin 6-producing myeloma cells.
Frassanito MA; Cusmai A; Piccoli C; Dammacco F
Br J Haematol; 2002 Jul; 118(1):157-65. PubMed ID: 12100143
[TBL] [Abstract][Full Text] [Related]
10. Manumycin enhances the cytotoxic effect of paclitaxel on anaplastic thyroid carcinoma cells.
Yeung SC; Xu G; Pan J; Christgen M; Bamiagis A
Cancer Res; 2000 Feb; 60(3):650-6. PubMed ID: 10676649
[TBL] [Abstract][Full Text] [Related]
11. [Growth inhibition of human pancreatic cancer by farnesyl transferase inhibitor].
Kainuma O; Asano T; Hasegawa M; Isono K
Gan To Kagaku Ryoho; 1996 Oct; 23(12):1657-9. PubMed ID: 8886038
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells.
Di Paolo A; Danesi R; Caputo S; Macchia M; Lastella M; Boggi U; Mosca F; Marchetti A; Del Tacca M
Br J Cancer; 2001 Jun; 84(11):1535-43. PubMed ID: 11384105
[TBL] [Abstract][Full Text] [Related]
13. Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies.
Sebti SM; Hamilton AD
Oncogene; 2000 Dec; 19(56):6584-93. PubMed ID: 11426643
[TBL] [Abstract][Full Text] [Related]
14. Blockade of the Ras pathway by manumycin, a farnesyltransferase inhibitor, overcomes the resistance of myeloma plasma cells to Fas-induced apoptosis.
Frassanito MA; Mastromauro L; Cusmai A; Dammacco F
Clin Exp Med; 2005 Mar; 4(4):174-82. PubMed ID: 15750764
[TBL] [Abstract][Full Text] [Related]
15. Suppression of human pancreatic cancer growth in BALB/c nude mice by manumycin, a farnesyl:protein transferase inhibitor.
Ito T; Kawata S; Tamura S; Igura T; Nagase T; Miyagawa JI; Yamazaki E; Ishiguro H; Matasuzawa Y
Jpn J Cancer Res; 1996 Feb; 87(2):113-6. PubMed ID: 8609057
[TBL] [Abstract][Full Text] [Related]
16. Chemopreventive efficacy of promising farnesyltransferase inhibitors.
Lantry LE; Zhang Z; Crist KA; Wang Y; Hara M; Zeeck A; Lubet RA; You M
Exp Lung Res; 2000 Dec; 26(8):773-90. PubMed ID: 11195470
[TBL] [Abstract][Full Text] [Related]
17. Akt-dependent antiapoptotic action of insulin is sensitive to farnesyltransferase inhibitor.
Park D; Pandey SK; Maksimova E; Kole S; Bernier M
Biochemistry; 2000 Oct; 39(41):12513-21. PubMed ID: 11027130
[TBL] [Abstract][Full Text] [Related]
18. Manumycin inhibits ras signal transduction pathway and induces apoptosis in COLO320-DM human colon tumour cells.
Di Paolo A; Danesi R; Nardini D; Bocci G; Innocenti F; Fogli S; Barachini S; Marchetti A; Bevilacqua G; Del Tacca M
Br J Cancer; 2000 Feb; 82(4):905-12. PubMed ID: 10732765
[TBL] [Abstract][Full Text] [Related]
19. Farnesyltransferase inhibitors reduce Ras activation and ameliorate acetaminophen-induced liver injury in mice.
Saha B; Nandi D
Hepatology; 2009 Nov; 50(5):1547-57. PubMed ID: 19739265
[TBL] [Abstract][Full Text] [Related]
20. Inhibiting the "Undruggable" RAS/Farnesyltransferase (FTase) Cancer Target by Manumycin-related Natural Products.
Silva LR; da Silva-Júnior EF
Curr Med Chem; 2022; 29(2):189-211. PubMed ID: 33719954
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
