335 related articles for article (PubMed ID: 12016543)
1. Regulation of hepatic drug metabolism: role of the nuclear receptors PXR and CAR.
Liddle C; Goodwin B
Semin Liver Dis; 2002; 22(2):115-22. PubMed ID: 12016543
[TBL] [Abstract][Full Text] [Related]
2. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
[TBL] [Abstract][Full Text] [Related]
3. PXR and CAR in energy metabolism.
Wada T; Gao J; Xie W
Trends Endocrinol Metab; 2009 Aug; 20(6):273-9. PubMed ID: 19595610
[TBL] [Abstract][Full Text] [Related]
4. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
[TBL] [Abstract][Full Text] [Related]
5. Induction of drug metabolism: the role of nuclear receptors.
Handschin C; Meyer UA
Pharmacol Rev; 2003 Dec; 55(4):649-73. PubMed ID: 14657421
[TBL] [Abstract][Full Text] [Related]
6. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
[TBL] [Abstract][Full Text] [Related]
7. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.
Echchgadda I; Song CS; Oh T; Ahmed M; De La Cruz IJ; Chatterjee B
Mol Endocrinol; 2007 Sep; 21(9):2099-111. PubMed ID: 17595319
[TBL] [Abstract][Full Text] [Related]
8. The PPARs and PXRs: nuclear xenobiotic receptors that define novel hormone signaling pathways.
Kliewer SA; Lehmann JM; Milburn MV; Willson TM
Recent Prog Horm Res; 1999; 54():345-67; discussion 367-8. PubMed ID: 10548883
[TBL] [Abstract][Full Text] [Related]
9. Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor.
Köhle C; Bock KW
Biochem Pharmacol; 2009 Feb; 77(4):689-99. PubMed ID: 18606396
[TBL] [Abstract][Full Text] [Related]
10. Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.
Wang H; LeCluyse EL
Clin Pharmacokinet; 2003; 42(15):1331-57. PubMed ID: 14674787
[TBL] [Abstract][Full Text] [Related]
11. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
Guo GL; Lambert G; Negishi M; Ward JM; Brewer HB; Kliewer SA; Gonzalez FJ; Sinal CJ
J Biol Chem; 2003 Nov; 278(46):45062-71. PubMed ID: 12923173
[TBL] [Abstract][Full Text] [Related]
12. P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
Waxman DJ
Arch Biochem Biophys; 1999 Sep; 369(1):11-23. PubMed ID: 10462436
[TBL] [Abstract][Full Text] [Related]
13. Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects.
di Masi A; De Marinis E; Ascenzi P; Marino M
Mol Aspects Med; 2009 Oct; 30(5):297-343. PubMed ID: 19427329
[TBL] [Abstract][Full Text] [Related]
14. Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio.
Modica S; Bellafante E; Moschetta A
Front Biosci (Landmark Ed); 2009 Jan; 14(12):4719-45. PubMed ID: 19273385
[TBL] [Abstract][Full Text] [Related]
15. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.
Stedman CA; Liddle C; Coulter SA; Sonoda J; Alvarez JG; Moore DD; Evans RM; Downes M
Proc Natl Acad Sci U S A; 2005 Feb; 102(6):2063-8. PubMed ID: 15684063
[TBL] [Abstract][Full Text] [Related]
16. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice.
Teng S; Piquette-Miller M
J Pharmacol Exp Ther; 2005 Feb; 312(2):841-8. PubMed ID: 15456840
[TBL] [Abstract][Full Text] [Related]
17. PXR, CAR and drug metabolism.
Willson TM; Kliewer SA
Nat Rev Drug Discov; 2002 Apr; 1(4):259-66. PubMed ID: 12120277
[TBL] [Abstract][Full Text] [Related]
18. Structural insights into the promiscuity and function of the human pregnane X receptor.
Watkins RE; Noble SM; Redinbo MR
Curr Opin Drug Discov Devel; 2002 Jan; 5(1):150-8. PubMed ID: 11865669
[TBL] [Abstract][Full Text] [Related]
19. Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response.
Moreau A; Vilarem MJ; Maurel P; Pascussi JM
Mol Pharm; 2008; 5(1):35-41. PubMed ID: 18159929
[TBL] [Abstract][Full Text] [Related]
20. Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1.
Braeuning A; Sanna R; Huelsken J; Schwarz M
Drug Metab Dispos; 2009 May; 37(5):1138-45. PubMed ID: 19237511
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]