BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 12019088)

  • 21. Efficacy of ASP2151, a helicase-primase inhibitor, against thymidine kinase-deficient herpes simplex virus type 2 infection in vitro and in vivo.
    Himaki T; Masui Y; Chono K; Daikoku T; Takemoto M; Haixia B; Okuda T; Suzuki H; Shiraki K
    Antiviral Res; 2012 Feb; 93(2):301-304. PubMed ID: 22155691
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection.
    Katsumata K; Chono K; Kato K; Ohtsu Y; Takakura S; Kontani T; Suzuki H
    Antimicrob Agents Chemother; 2013 Mar; 57(3):1339-46. PubMed ID: 23274658
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Inhibition of herpes simplex virus replication by a 2-amino thiazole via interactions with the helicase component of the UL5-UL8-UL52 complex.
    Spector FC; Liang L; Giordano H; Sivaraja M; Peterson MG
    J Virol; 1998 Sep; 72(9):6979-87. PubMed ID: 9696789
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Characterization of virus strains resistant to the herpes virus helicase-primase inhibitor ASP2151 (Amenamevir).
    Chono K; Katsumata K; Kontani T; Shiraki K; Suzuki H
    Biochem Pharmacol; 2012 Aug; 84(4):459-67. PubMed ID: 22687623
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Antiviral efficacy of the helicase-primase inhibitor amenamevir in murine models of severe herpesvirus infection.
    Katsumata K; Chono K; Suzuki H
    Biochem Pharmacol; 2018 Dec; 158():201-206. PubMed ID: 30365949
    [TBL] [Abstract][Full Text] [Related]  

  • 26. New antiviral drugs that target herpesvirus helicase primase enzymes.
    Kleymann G
    Herpes; 2003 Aug; 10(2):46-52. PubMed ID: 14577954
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Helicase-primase inhibitor amenamevir for herpesvirus infection: Towards practical application for treating herpes zoster.
    Shiraki K
    Drugs Today (Barc); 2017 Nov; 53(11):573-584. PubMed ID: 29451274
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase.
    Liuzzi M; Kibler P; Bousquet C; Harji F; Bolger G; Garneau M; Lapeyre N; McCollum RS; Faucher AM; Simoneau B; Cordingley MG
    Antiviral Res; 2004 Dec; 64(3):161-70. PubMed ID: 15550269
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant.
    Sukla S; Biswas S; Birkmann A; Lischka P; Ruebsamen-Schaeff H; Zimmermann H; Field HJ
    Antiviral Res; 2010 Jul; 87(1):67-73. PubMed ID: 20420855
    [TBL] [Abstract][Full Text] [Related]  

  • 30. New anti-HSV therapeutics target the helicase-primase complex.
    Crumpacker CS; Schaffer PA
    Nat Med; 2002 Apr; 8(4):327-8. PubMed ID: 11927930
    [No Abstract]   [Full Text] [Related]  

  • 31. Profile of anti-herpetic action of ASP2151 (amenamevir) as a helicase-primase inhibitor.
    Yajima M; Yamada H; Takemoto M; Daikoku T; Yoshida Y; Long T; Okuda T; Shiraki K
    Antiviral Res; 2017 Mar; 139():95-101. PubMed ID: 28027917
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations.
    Biswas S; Field HJ
    Antivir Chem Chemother; 2008; 19(1):1-6. PubMed ID: 18610552
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Susceptibility of herpes simplex virus isolated from genital herpes lesions to ASP2151, a novel helicase-primase inhibitor.
    Katsumata K; Weinberg A; Chono K; Takakura S; Kontani T; Suzuki H
    Antimicrob Agents Chemother; 2012 Jul; 56(7):3587-91. PubMed ID: 22526302
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Drugs in development for herpes simplex and varicella zoster virus.
    Birkmann A; Zimmermann H
    Clin Pharmacol Ther; 2017 Jul; 102(1):30-32. PubMed ID: 28160282
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Efficacy of herpes virus helicase-primase inhibitor, ASP2151, for treating herpes simplex keratitis in mouse model.
    Sasaki S; Miyazaki D; Haruki T; Yamamoto Y; Kandori M; Yakura K; Suzuki H; Inoue Y
    Br J Ophthalmol; 2013 Apr; 97(4):498-503. PubMed ID: 23361434
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Use of pritelivir in refractory aciclovir-resistant herpes simplex virus type 2.
    Cannon L; Tholouli E; Ward C; Farooq H; Kingston M
    Int J STD AIDS; 2021 Sep; 32(10):978-980. PubMed ID: 33947276
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Antiviral drug resistance and helicase-primase inhibitors of herpes simplex virus.
    Field HJ; Biswas S
    Drug Resist Updat; 2011 Feb; 14(1):45-51. PubMed ID: 21183396
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure.
    Biswas S; Miguel RN; Sukla S; Field HJ
    J Gen Virol; 2009 Aug; 90(Pt 8):1937-1942. PubMed ID: 19403757
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis.
    Quenelle DC; Birkmann A; Goldner T; Pfaff T; Zimmermann H; Bonsmann S; Collins DJ; Rice TL; Prichard MN
    Antiviral Res; 2018 Jan; 149():1-6. PubMed ID: 29113740
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1.
    Biswas S; Smith C; Field HJ
    J Antimicrob Chemother; 2007 Aug; 60(2):274-9. PubMed ID: 17550887
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.