BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 12020135)

  • 1. Use of kinetic isotope effects to delineate the role of phenylalanine 87 in P450(BM-3).
    Rock DA; Boitano AE; Wahlstrom JL; Rock DA; Jones JP
    Bioorg Chem; 2002 Apr; 30(2):107-18. PubMed ID: 12020135
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
    Gustafsson MC; Roitel O; Marshall KR; Noble MA; Chapman SK; Pessegueiro A; Fulco AJ; Cheesman MR; von Wachenfeldt C; Munro AW
    Biochemistry; 2004 May; 43(18):5474-87. PubMed ID: 15122913
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Affinity isolation and characterization of cytochrome P450 102 (BM-3) from barbiturate-induced Bacillus megaterium.
    Black SD; Linger MH; Freck LC; Kazemi S; Galbraith JA
    Arch Biochem Biophys; 1994 Apr; 310(1):126-33. PubMed ID: 8161195
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
    Huang WC; Westlake AC; Maréchal JD; Joyce MG; Moody PC; Roberts GC
    J Mol Biol; 2007 Oct; 373(3):633-51. PubMed ID: 17868686
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A continuous spectrophotometric assay for P450 BM-3, a fatty acid hydroxylating enzyme, and its mutant F87A.
    Schwaneberg U; Schmidt-Dannert C; Schmitt J; Schmid RD
    Anal Biochem; 1999 May; 269(2):359-66. PubMed ID: 10222011
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3.
    Peters MW; Meinhold P; Glieder A; Arnold FH
    J Am Chem Soc; 2003 Nov; 125(44):13442-50. PubMed ID: 14583039
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation.
    Oliver CF; Modi S; Sutcliffe MJ; Primrose WU; Lian LY; Roberts GC
    Biochemistry; 1997 Feb; 36(7):1567-72. PubMed ID: 9048540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. On the domain structure of cytochrome P450 102 (BM-3): isolation and properties of a 45-kDa FAD/NADP domain.
    Black SD
    Biochem Biophys Res Commun; 1994 Aug; 203(1):162-8. PubMed ID: 8074651
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein engineering of the cytochrome P450 monooxygenase from Bacillus megaterium.
    Urlacher VB; Schmid RD
    Methods Enzymol; 2004; 388():208-24. PubMed ID: 15289074
    [No Abstract]   [Full Text] [Related]  

  • 10. Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
    Roitel O; Scrutton NS; Munro AW
    Biochemistry; 2003 Sep; 42(36):10809-21. PubMed ID: 12962506
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities.
    Yun CH; Kim KH; Kim DH; Jung HC; Pan JG
    Trends Biotechnol; 2007 Jul; 25(7):289-98. PubMed ID: 17532492
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Laboratory evolution of P450 BM-3 for mediated electron transfer.
    Nazor J; Schwaneberg U
    Chembiochem; 2006 Apr; 7(4):638-44. PubMed ID: 16521141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Critical role of the residue size at position 87 in H2O2- dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3.
    Li QS; Ogawa J; Shimizu S
    Biochem Biophys Res Commun; 2001 Feb; 280(5):1258-61. PubMed ID: 11162663
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Toward understanding the inactivation mechanism of monooxygenase P450 BM-3 by organic cosolvents: a molecular dynamics simulation study.
    Roccatano D; Wong TS; Schwaneberg U; Zacharias M
    Biopolymers; 2006 Dec; 83(5):467-76. PubMed ID: 16862534
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A three-dimensional protein model for human cytochrome P450 2D6 based on the crystal structures of P450 101, P450 102, and P450 108.
    de Groot MJ; Vermeulen NP; Kramer JD; van Acker FA; Donné-Op den Kelder GM
    Chem Res Toxicol; 1996; 9(7):1079-91. PubMed ID: 8902262
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Obligatory intermolecular electron-transfer from FAD to FMN in dimeric P450BM-3.
    Kitazume T; Haines DC; Estabrook RW; Chen B; Peterson JA
    Biochemistry; 2007 Oct; 46(42):11892-901. PubMed ID: 17902705
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxygen activation by cytochrome P450BM-3: effects of mutating an active site acidic residue.
    Yeom H; Sligar SG
    Arch Biochem Biophys; 1997 Jan; 337(2):209-16. PubMed ID: 9016815
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Laboratory evolution of cytochrome p450 BM-3 monooxygenase for organic cosolvents.
    Wong TS; Arnold FH; Schwaneberg U
    Biotechnol Bioeng; 2004 Feb; 85(3):351-8. PubMed ID: 14748091
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intramolecular isotope effects for benzylic hydroxylation of isomeric xylenes and 4,4'-dimethylbiphenyl by cytochrome P450: relationship between distance of methyl groups and masking of the intrinsic isotope effect.
    Iyer KR; Jones JP; Darbyshire JF; Trager WF
    Biochemistry; 1997 Jun; 36(23):7136-43. PubMed ID: 9188713
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thr268 in substrate binding and catalysis in P450BM-3.
    Truan G; Peterson JA
    Arch Biochem Biophys; 1998 Jan; 349(1):53-64. PubMed ID: 9439582
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.