BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 12020162)

  • 1. How might qinghaosu (artemisinin) and related compounds kill the intraerythrocytic malaria parasite? A chemist's view.
    Wu Y
    Acc Chem Res; 2002 May; 35(5):255-9. PubMed ID: 12020162
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.
    Haynes RK; Cheu KW; N'Da D; Coghi P; Monti D
    Infect Disord Drug Targets; 2013 Aug; 13(4):217-77. PubMed ID: 24304352
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanism(s) of action.
    Cumming JN; Ploypradith P; Posner GH
    Adv Pharmacol; 1997; 37():253-97. PubMed ID: 8891104
    [No Abstract]   [Full Text] [Related]  

  • 4. An over four millennium story behind qinghaosu (artemisinin)--a fantastic antimalarial drug from a traditional chinese herb.
    Li Y; Wu YL
    Curr Med Chem; 2003 Nov; 10(21):2197-230. PubMed ID: 14529339
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin.
    Parapini S; Basilico N; Mondani M; Olliaro P; Taramelli D; Monti D
    FEBS Lett; 2004 Sep; 575(1-3):91-4. PubMed ID: 15388339
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Progress in studies on the artemisinin (qinghaosu)-type antimalarials].
    Chen Y; Zhu SM; Chen HY
    Yao Xue Xue Bao; 1998; 33(3):234-9. PubMed ID: 11938970
    [No Abstract]   [Full Text] [Related]  

  • 7. Quinolines and artemisinin: chemistry, biology and history.
    Bray PG; Ward SA; O'Neill PM
    Curr Top Microbiol Immunol; 2005; 295():3-38. PubMed ID: 16265885
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular modeling studies of the artemisinin (qinghaosu)-hemin interaction: docking between the antimalarial agent and its putative receptor.
    Shukla KL; Gund TM; Meshnick SR
    J Mol Graph; 1995 Aug; 13(4):215-22. PubMed ID: 8527414
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Probing the possible molecular origin of the highly selective toxicity of antimalarial peroxide qinghaosu (artemisinin).
    Wu Y; Liu HH
    Chem Res Toxicol; 2003 Oct; 16(10):1202-6. PubMed ID: 14565761
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular docking and 3-D-QSAR studies on the possible antimalarial mechanism of artemisinin analogues.
    Cheng F; Shen J; Luo X; Zhu W; Gu J; Ji R; Jiang H; Chen K
    Bioorg Med Chem; 2002 Sep; 10(9):2883-91. PubMed ID: 12110308
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity.
    Haynes RK; Ho WY; Chan HW; Fugmann B; Stetter J; Croft SL; Vivas L; Peters W; Robinson BL
    Angew Chem Int Ed Engl; 2004 Mar; 43(11):1381-5. PubMed ID: 15368412
    [No Abstract]   [Full Text] [Related]  

  • 12. EPR evidence for the involvement of free radicals in the iron-catalysed decomposition of qinghaosu (artemisinin) and some derivatives; antimalarial action of some polycyclic endoperoxides.
    Butler AR; Gilbert BC; Hulme P; Irvine LR; Renton L; Whitwood AC
    Free Radic Res; 1998 May; 28(5):471-6. PubMed ID: 9702527
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Knowledge of the proposed chemical mechanism of action and cytochrome p450 metabolism of antimalarial trioxanes like artemisinin allows rational design of new antimalarial peroxides.
    Posner GH; O'Neill PM
    Acc Chem Res; 2004 Jun; 37(6):397-404. PubMed ID: 15196049
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Artemisinin antimalarials: mechanisms of action and resistance.
    Meshnick SR
    Med Trop (Mars); 1998; 58(3 Suppl):13-7. PubMed ID: 10212891
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.
    Avery MA; Muraleedharan KM; Desai PV; Bandyopadhyaya AK; Furtado MM; Tekwani BL
    J Med Chem; 2003 Sep; 46(20):4244-58. PubMed ID: 13678403
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Qinghaosu in combinations.
    White NJ
    Med Trop (Mars); 1998; 58(3 Suppl):85-8. PubMed ID: 10212909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. How Chinese scientists discovered qinghaosu (artemisinin) and developed its derivatives? What are the future perspectives?
    Li Y; Wu YL
    Med Trop (Mars); 1998; 58(3 Suppl):9-12. PubMed ID: 10212890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Recent advances in the study of artemisinin-related 1,2,4-trioxanes and ozonides (1,2,4-trioxolanes) as antimalarials].
    Yang ZS; Li Y
    Yao Xue Xue Bao; 2005 Dec; 40(12):1057-63. PubMed ID: 16496665
    [No Abstract]   [Full Text] [Related]  

  • 19. Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action.
    Haynes RK; Chan WC; Wong HN; Li KY; Wu WK; Fan KM; Sung HH; Williams ID; Prosperi D; Melato S; Coghi P; Monti D
    ChemMedChem; 2010 Aug; 5(8):1282-99. PubMed ID: 20629071
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Artemisone--a highly active antimalarial drug of the artemisinin class.
    Haynes RK; Fugmann B; Stetter J; Rieckmann K; Heilmann HD; Chan HW; Cheung MK; Lam WL; Wong HN; Croft SL; Vivas L; Rattray L; Stewart L; Peters W; Robinson BL; Edstein MD; Kotecka B; Kyle DE; Beckermann B; Gerisch M; Radtke M; Schmuck G; Steinke W; Wollborn U; Schmeer K; Römer A
    Angew Chem Int Ed Engl; 2006 Mar; 45(13):2082-8. PubMed ID: 16444785
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 12.