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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

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  • 1. Ask the doctor. I read a lot about cardiovascular disease and hear so much different advice that it's tough to know what to do. I am basically healthy, but I have a lot of heart disease in my family. Can you give me a simple set of recommendations that will help me avoid heart disease?
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  • 2. Ask the doctor. I am generally healthy, but I had a heart attack last year. At my age, 78 years old, I find it hard to take it seriously when my doctor and my children tell me that I should be lowering my cholesterol and exercising. It seems to me that the idea of trying to prevent "premature" death is silly in someone my age. It's not like I feel ready to die, but it's hard for me to believe that prevention works in someone who has already gone beyond his "three score ten" years.
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  • 3. By the way, doctor. I am 59 years old, in good health, and have been on HRT (estrogen and progesterone) for about 10 years. I have tried several different preparations, but despite this, have developed a uterine fibroid, experienced indigestion, gained 20 pounds, and had one abnormal mammogram (with, thankfully, a negative biopsy). Because there is heart disease in my family, my doctor wants me to stay on HRT for the rest of my life. Can you suggest any alternatives?
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  • 11. Ask the doctor. My doctor and I are confused by my cholesterol levels. My good cholesterol is extraordinarily high, at 94, but my bad cholesterol is on the high side, too, at 154. To resolve this good news/bad news story, my doctor ordered a C-reactive protein test which, of course, came back right in the middle of the normal range. I don't smoke or have other factors for heart disease. Would you advise me at start a statin or some other drug?
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  • 13. Ask the Doctor. I have read in your newsletter that poor dental health can contribute to heart disease. I have always done my best with my teeth, including flossing three times a day, but still have a serious problem with gum recession and have lost a few teeth. I don t have other risk factors for heart disease. Do my dental problems raise my risk for a heart attack?
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  • 14. Ask the doctor. I haven't had such good luck with my heart--a heart attack ten years ago and angioplasty with two stents inserted last year. Would it make sense for me to have a yearly stress test? If I had been doing that after my heart attack, maybe my doctor would have seen the blockage and we could have done something about it earlier.
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  • 15. Ask the doctor. While I was getting my teeth cleaned, the dental hygienists asked me about my heart condition. She seemed surprised when I told her I had a healthy heart, because she said I had creases on both my earlobes. Is this an urban legend, or is it something I should be worried about?
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