165 related articles for article (PubMed ID: 12021103)
1. The PEVKEK region of the pyridoxal phosphate binding domain of GAD65 expresses a dominant B cell epitope for type 1 diabetes sera.
Tong JC; Myers MA; Mackay IR; Zimmet PZ; Rowley MJ
Ann N Y Acad Sci; 2002 Apr; 958():182-9. PubMed ID: 12021103
[TBL] [Abstract][Full Text] [Related]
2. Conformational epitopes on the diabetes autoantigen GAD65 identified by peptide phage display and molecular modeling.
Myers MA; Davies JM; Tong JC; Whisstock J; Scealy M; Mackay IR; Rowley MJ
J Immunol; 2000 Oct; 165(7):3830-8. PubMed ID: 11034389
[TBL] [Abstract][Full Text] [Related]
3. Molecular mimicry in diabetes mellitus: the homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule.
Vreugdenhil GR; Geluk A; Ottenhoff TH; Melchers WJ; Roep BO; Galama JM
Diabetologia; 1998 Jan; 41(1):40-6. PubMed ID: 9498628
[TBL] [Abstract][Full Text] [Related]
4. Autoantigenic reactivity of diabetes sera with a hybrid glutamic acid decarboxylase GAD67-65 molecule GAD67(1-101)/GAD65(96-585).
Teoh KL; Fida S; Rowley MJ; Mackay IR
Autoimmunity; 1998; 28(4):259-66. PubMed ID: 9892508
[TBL] [Abstract][Full Text] [Related]
5. A diabetes-related epitope of GAD65: a major diabetes-related conformational epitope on GAD65.
Myers MA; Fenalti G; Gray R; Scealy M; Tong JC; El-Kabbani O; Rowley MJ
Ann N Y Acad Sci; 2003 Nov; 1005():250-2. PubMed ID: 14679070
[TBL] [Abstract][Full Text] [Related]
6. Antibody cross-reactivity induced by the homologous regions in glutamic acid decarboxylase (GAD65) and 2C protein of coxsackievirus B4. Childhood Diabetes in Finland Study Group.
Lönnrot M; Hyöty H; Knip M; Roivainen M; Kulmala P; Leinikki P; Akerblom HK
Clin Exp Immunol; 1996 Jun; 104(3):398-405. PubMed ID: 9099922
[TBL] [Abstract][Full Text] [Related]
7. Antibodies to glutamic acid decarboxylase and P2-C peptides in sera from coxsackie virus B4-infected mice and IDDM patients.
Hou J; Said C; Franchi D; Dockstader P; Chatterjee NK
Diabetes; 1994 Oct; 43(10):1260-6. PubMed ID: 7523207
[TBL] [Abstract][Full Text] [Related]
8. COOH-terminal clustering of autoantibody and T-cell determinants on the structure of GAD65 provide insights into the molecular basis of autoreactivity.
Fenalti G; Hampe CS; Arafat Y; Law RH; Banga JP; Mackay IR; Whisstock JC; Buckle AM; Rowley MJ
Diabetes; 2008 May; 57(5):1293-301. PubMed ID: 18184926
[TBL] [Abstract][Full Text] [Related]
9. Structural determinants of GAD antigenicity.
Arafat Y; Fenalti G; Whisstock JC; Mackay IR; Garcia de la Banda M; Rowley MJ; Buckle AM
Mol Immunol; 2009 Dec; 47(2-3):493-505. PubMed ID: 19783309
[TBL] [Abstract][Full Text] [Related]
10. Site-directed mutagenesis of K396R of the 65 kDa glutamic acid decarboxylase active site obliterates enzyme activity but not antibody binding.
Hampe CS; Hammerle LP; Falorni A; Robertson J; Lernmark A
FEBS Lett; 2001 Jan; 488(3):185-9. PubMed ID: 11163769
[TBL] [Abstract][Full Text] [Related]
11. An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes.
Jayakrishnan B; Hoke DE; Langendorf CG; Buckle AM; Rowley MJ
PLoS One; 2011 Apr; 6(4):e18411. PubMed ID: 21494613
[TBL] [Abstract][Full Text] [Related]
12. Unique epitopes of glutamic acid decarboxylase autoantibodies in slowly progressive type 1 diabetes.
Kobayashi T; Tanaka S; Okubo M; Nakanishi K; Murase T; Lernmark A
J Clin Endocrinol Metab; 2003 Oct; 88(10):4768-75. PubMed ID: 14557453
[TBL] [Abstract][Full Text] [Related]
13. Identification of glutamic acid decarboxylase autoantibody heterogeneity and epitope regions in type I diabetes.
Ujihara N; Daw K; Gianani R; Boel E; Yu L; Powers AC
Diabetes; 1994 Aug; 43(8):968-75. PubMed ID: 8039604
[TBL] [Abstract][Full Text] [Related]
14. Responses of coxsackievirus B4-specific T-cell lines to 2C protein-characterization of epitopes with special reference to the GAD65 homology region.
Marttila J; Juhela S; Vaarala O; Hyöty H; Roivainen M; Hinkkanen A; Vilja P; Simell O; Ilonen J
Virology; 2001 May; 284(1):131-41. PubMed ID: 11352674
[TBL] [Abstract][Full Text] [Related]
15. Immune reactivity to GAD25 in type 1 diabetes mellitus.
Chessler SD; Hampe CS; Ortqvist E; Simonson WT; Bekris L
Autoimmunity; 2002 Aug; 35(5):335-41. PubMed ID: 12515288
[TBL] [Abstract][Full Text] [Related]
16. High-resolution autoreactive epitope mapping and structural modeling of the 65 kDa form of human glutamic acid decarboxylase.
Schwartz HL; Chandonia JM; Kash SF; Kanaani J; Tunnell E; Domingo A; Cohen FE; Banga JP; Madec AM; Richter W; Baekkeskov S
J Mol Biol; 1999 Apr; 287(5):983-99. PubMed ID: 10222205
[TBL] [Abstract][Full Text] [Related]
17. Fusion proteins for combined analysis of autoantibodies to the 65-kDa isoform of glutamic acid decarboxylase and islet antigen-2 in insulin-dependent diabetes mellitus.
Rickert M; Seissler J; Dangel W; Lorenz H; Richter W
Clin Chem; 2001 May; 47(5):926-34. PubMed ID: 11325898
[TBL] [Abstract][Full Text] [Related]
18. Recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different GAD antibody-positive phenotypes.
Hampe CS; Hammerle LP; Bekris L; Ortqvist E; Kockum I; Rolandsson O; Landin-Olsson M; Törn C; Persson B; Lernmark A
J Clin Endocrinol Metab; 2000 Dec; 85(12):4671-9. PubMed ID: 11134126
[TBL] [Abstract][Full Text] [Related]
19. Molecular characterization of a disease associated conformational epitope on GAD65 recognised by a human monoclonal antibody b96.11.
Fenalti G; Hampe CS; O'connor K; Banga JP; Mackay IR; Rowley MJ; El-Kabbani O
Mol Immunol; 2007 Feb; 44(6):1178-89. PubMed ID: 16930708
[TBL] [Abstract][Full Text] [Related]
20. Engineered variants of human glutamic acid decarboxylase (GAD) and autoantibody epitope recognition.
Primo ME; Anton EA; Villanueva AL; Poskus E; Ermácora MR
Clin Immunol; 2003 Jul; 108(1):38-45. PubMed ID: 12865069
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
