BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

420 related articles for article (PubMed ID: 12021361)

  • 1. Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.
    Gorry PR; Taylor J; Holm GH; Mehle A; Morgan T; Cayabyab M; Farzan M; Wang H; Bell JE; Kunstman K; Moore JP; Wolinsky SM; Gabuzda D
    J Virol; 2002 Jun; 76(12):6277-92. PubMed ID: 12021361
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.
    Quitadamo B; Peters PJ; Repik A; O'Connell O; Mou Z; Koch M; Somasundaran M; Brody R; Luzuriaga K; Wallace A; Wang S; Lu S; McCauley S; Luban J; Duenas-Decamp M; Gonzalez-Perez MP; Clapham PR
    J Virol; 2018 Jan; 92(2):. PubMed ID: 29118121
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.
    Sterjovski J; Churchill MJ; Ellett A; Gray LR; Roche MJ; Dunfee RL; Purcell DF; Saksena N; Wang B; Sonza S; Wesselingh SL; Karlsson I; Fenyo EM; Gabuzda D; Cunningham AL; Gorry PR
    Retrovirology; 2007 Dec; 4():89. PubMed ID: 18076768
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion.
    Thomas ER; Dunfee RL; Stanton J; Bogdan D; Taylor J; Kunstman K; Bell JE; Wolinsky SM; Gabuzda D
    Virology; 2007 Mar; 360(1):105-19. PubMed ID: 17084877
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity.
    Gorry PR; Bristol G; Zack JA; Ritola K; Swanstrom R; Birch CJ; Bell JE; Bannert N; Crawford K; Wang H; Schols D; De Clercq E; Kunstman K; Wolinsky SM; Gabuzda D
    J Virol; 2001 Nov; 75(21):10073-89. PubMed ID: 11581376
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain.
    Gray L; Roche M; Churchill MJ; Sterjovski J; Ellett A; Poumbourios P; Sherieff S; Wang B; Saksena N; Purcell DF; Wesselingh S; Cunningham AL; Brew BJ; Gabuzda D; Gorry PR
    J Virol; 2009 Jun; 83(11):5430-41. PubMed ID: 19321618
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusigenicity for macrophages.
    Peters PJ; Bhattacharya J; Hibbitts S; Dittmar MT; Simmons G; Bell J; Simmonds P; Clapham PR
    J Virol; 2004 Jul; 78(13):6915-26. PubMed ID: 15194768
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression.
    LaBonte JA; Madani N; Sodroski J
    J Virol; 2003 Jun; 77(12):6645-59. PubMed ID: 12767984
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phenotypic Correlates of HIV-1 Macrophage Tropism.
    Arrildt KT; LaBranche CC; Joseph SB; Dukhovlinova EN; Graham WD; Ping LH; Schnell G; Sturdevant CB; Kincer LP; Mallewa M; Heyderman RS; Rie AV; Cohen MS; Spudich S; Price RW; Montefiori DC; Swanstrom R
    J Virol; 2015 Nov; 89(22):11294-311. PubMed ID: 26339058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Macrophage-tropic HIV-1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5.
    Salimi H; Roche M; Webb N; Gray LR; Chikere K; Sterjovski J; Ellett A; Wesselingh SL; Ramsland PA; Lee B; Churchill MJ; Gorry PR
    J Leukoc Biol; 2013 Jan; 93(1):113-26. PubMed ID: 23077246
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants.
    Smit TK; Wang B; Ng T; Osborne R; Brew B; Saksena NK
    Virology; 2001 Jan; 279(2):509-26. PubMed ID: 11162807
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HIV-1 tropism for the central nervous system: Brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor.
    Martín-García J; Cao W; Varela-Rohena A; Plassmeyer ML; González-Scarano F
    Virology; 2006 Mar; 346(1):169-79. PubMed ID: 16309726
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds.
    Madani N; Princiotto AM; Zhao C; Jahanbakhshsefidi F; Mertens M; Herschhorn A; Melillo B; Smith AB; Sodroski J
    J Virol; 2017 Feb; 91(3):. PubMed ID: 27881646
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity.
    Puffer BA; Pöhlmann S; Edinger AL; Carlin D; Sanchez MD; Reitter J; Watry DD; Fox HS; Desrosiers RC; Doms RW
    J Virol; 2002 Mar; 76(6):2595-605. PubMed ID: 11861825
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome.
    Gray L; Sterjovski J; Churchill M; Ellery P; Nasr N; Lewin SR; Crowe SM; Wesselingh SL; Cunningham AL; Gorry PR
    Virology; 2005 Jul; 337(2):384-98. PubMed ID: 15916792
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Variation of macrophage tropism among HIV-1 R5 envelopes in brain and other tissues.
    Peters PJ; Dueñas-Decamp MJ; Sullivan WM; Clapham PR
    J Neuroimmune Pharmacol; 2007 Mar; 2(1):32-41. PubMed ID: 18040824
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains.
    Shieh JT; Martín J; Baltuch G; Malim MH; González-Scarano F
    J Virol; 2000 Jan; 74(2):693-701. PubMed ID: 10623731
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS.
    Ohagen A; Devitt A; Kunstman KJ; Gorry PR; Rose PP; Korber B; Taylor J; Levy R; Murphy RL; Wolinsky SM; Gabuzda D
    J Virol; 2003 Nov; 77(22):12336-45. PubMed ID: 14581570
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Decreased plasticity of coreceptor use by CD4-independent SIV Envs that emerge in vivo.
    Francella N; Elliott ST; Yi Y; Gwyn SE; Ortiz AM; Li B; Silvestri G; Paiardini M; Derdeyn CA; Collman RG
    Retrovirology; 2013 Nov; 10():133. PubMed ID: 24219995
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Concordant utilization of macrophage entry coreceptors by related variants within an HIV type 1 primary isolate viral swarm.
    Singh A; Yi Y; Isaacs SN; Kolson DL; Collman RG
    AIDS Res Hum Retroviruses; 2001 Jul; 17(10):957-63. PubMed ID: 11461681
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.