These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 12023549)

  • 1. 5-Hydroxytryptamine1A receptor occupancy by novel full antagonist 2-[4-[4-(7-chloro-2,3-dihydro-1,4-benzdioxyn-5-yl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3-(2H)-one-1,1-dioxide: a[11C][O-methyl-3H]-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide trihydrochloride (WAY-100635) positron emission tomography study in humans.
    Rabiner EA; Wilkins MR; Turkheimer F; Gunn RN; Udo de Haes J; de Vries M; Grasby PM
    J Pharmacol Exp Ther; 2002 Jun; 301(3):1144-50. PubMed ID: 12023549
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635.
    Rabiner EA; Gunn RN; Wilkins MR; Sargent PA; Mocaer E; Sedman E; Cowen PJ; Grasby PM
    Nucl Med Biol; 2000 Jul; 27(5):509-13. PubMed ID: 10962259
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of PET and the radioligand [carbonyl-(11)C]WAY-100635 in psychotropic drug development.
    Andrée B; Halldin C; Thorberg SO; Sandell J; Farde L
    Nucl Med Biol; 2000 Jul; 27(5):515-21. PubMed ID: 10962260
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Positron emission tomography study of pindolol occupancy of 5-HT(1A) receptors in humans: preliminary analyses.
    Martinez D; Mawlawi O; Hwang DR; Kent J; Simpson N; Parsey RV; Hashimoto T; Slifstein M; Huang Y; Van Heertum R; Abi-Dargham A; Caltabiano S; Malizia A; Cowley H; Mann JJ; Laruelle M
    Nucl Med Biol; 2000 Jul; 27(5):523-7. PubMed ID: 10962261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Brain serotonin 5-HT(1A) receptor binding in schizophrenia measured by positron emission tomography and [11C]WAY-100635.
    Tauscher J; Kapur S; Verhoeff NP; Hussey DF; Daskalakis ZJ; Tauscher-Wisniewski S; Wilson AA; Houle S; Kasper S; Zipursky RB
    Arch Gen Psychiatry; 2002 Jun; 59(6):514-20. PubMed ID: 12044193
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of [O-methyl-3H]WAY-100635 as an in vivo radioligand for 5-HT1A receptors in rat brain.
    Hume SP; Ashworth S; Opacka-Juffry J; Ahier RG; Lammertsma AA; Pike VW; Cliffe IA; Fletcher A; White AC
    Eur J Pharmacol; 1994 Dec; 271(2-3):515-23. PubMed ID: 7705452
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Serotonin type-1A receptor imaging in depression.
    Drevets WC; Frank E; Price JC; Kupfer DJ; Greer PJ; Mathis C
    Nucl Med Biol; 2000 Jul; 27(5):499-507. PubMed ID: 10962258
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635.
    Hall H; Lundkvist C; Halldin C; Farde L; Pike VW; McCarron JA; Fletcher A; Cliffe IA; Barf T; Wikström H; Sedvall G
    Brain Res; 1997 Jan; 745(1-2):96-108. PubMed ID: 9037397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pindolol occupancy of 5-HT(1A) receptors measured in vivo using small animal positron emission tomography with carbon-11 labeled WAY 100635.
    Hirani E; Opacka-Juffry J; Gunn R; Khan I; Sharp T; Hume S
    Synapse; 2000 Jun; 36(4):330-41. PubMed ID: 10819911
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of several 5-hydroxytryptamine(1A) receptor ligands on the micturition reflex in rats: comparison with WAY 100635.
    Testa R; Guarneri L; Poggesi E; Angelico P; Velasco C; Ibba M; Cilia A; Motta G; Riva C; Leonardi A
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1258-69. PubMed ID: 10454502
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Positron emission tomographic analysis of dose-dependent NAD-299 binding to 5-hydroxytryptamine-1A receptors in the human brain.
    Andrée B; Hedman A; Thorberg SO; Nilsson D; Halldin C; Farde L
    Psychopharmacology (Berl); 2003 Apr; 167(1):37-45. PubMed ID: 12632244
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PET evaluation of [(18)F]FCWAY, an analog of the 5-HT(1A) receptor antagonist, WAY-100635.
    Carson RE; Lang L; Watabe H; Der MG; Adams HR; Jagoda E; Herscovitch P; Eckelman WC
    Nucl Med Biol; 2000 Jul; 27(5):493-7. PubMed ID: 10962257
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Correlating efficacy in rodent cognition models with in vivo 5-hydroxytryptamine1a receptor occupancy by a novel antagonist, (R)-N-(2-methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane carboxamide (WAY-101405).
    Hirst WD; Andree TH; Aschmies S; Childers WE; Comery TA; Dawson LA; Day M; Feingold IB; Grauer SM; Harrison BL; Hughes ZA; Kao J; Kelly MG; van der Lee H; Rosenzweig-Lipson S; Saab AL; Smith DL; Sullivan K; Rizzo SJ; Tio C; Zhang MY; Schechter LE
    J Pharmacol Exp Ther; 2008 Apr; 325(1):134-45. PubMed ID: 18182558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. WAY-100635 antagonist-induced plasticity of 5-HT receptors: regulatory differences between a stable cell line and an in vivo native system.
    Khawaja XZ; Smith DL; Nawoschik SP; Zhang J; Dunlop J; Dilks DW; Olsen M; Schechter LE
    J Neurochem; 2006 Jul; 98(1):134-45. PubMed ID: 16805803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey.
    Sandell J; Halldin C; Pike VW; Chou YH; Varnäs K; Hall H; Marchais S; Nowicki B; Wikström HV; Swahn CG; Farde L
    Nucl Med Biol; 2001 Feb; 28(2):177-85. PubMed ID: 11295428
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Efficacy of antipsychotic agents at human 5-HT(1A) receptors determined by [3H]WAY100,635 binding affinity ratios: relationship to efficacy for G-protein activation.
    Newman-Tancredi A; Verrièle L; Touzard M; Millan MJ
    Eur J Pharmacol; 2001 Oct; 428(2):177-84. PubMed ID: 11675034
    [TBL] [Abstract][Full Text] [Related]  

  • 17. beta-blocker binding to human 5-HT(1A) receptors in vivo and in vitro: implications for antidepressant therapy.
    Rabiner EA; Gunn RN; Castro ME; Sargent PA; Cowen PJ; Koepp MJ; Meyer JH; Bench CJ; Harrison PJ; Pazos A; Sharp T; Grasby PM
    Neuropsychopharmacology; 2000 Sep; 23(3):285-93. PubMed ID: 10942852
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists.
    Marchais-Oberwinkler S; Nowicki B; Pike VW; Halldin C; Sandell J; Chou YH; Gulyas B; Brennum LT; Farde L; Wikström HV
    Bioorg Med Chem; 2005 Feb; 13(3):883-93. PubMed ID: 15653354
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain.
    Corradetti R; Laaris N; Hanoun N; Laporte AM; Le Poul E; Hamon M; Lanfumey L
    Br J Pharmacol; 1998 Feb; 123(3):449-62. PubMed ID: 9504386
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PET-Determination of robalzotan (NAD-299) induced 5-HT(1A) receptor occupancy in the monkey brain.
    Farde L; Andrée B; Ginovart N; Halldin C; Thorberg S
    Neuropsychopharmacology; 2000 Apr; 22(4):422-9. PubMed ID: 10700661
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.