307 related articles for article (PubMed ID: 12023960)
1. Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo.
Lizcano JM; Deak M; Morrice N; Kieloch A; Hastie CJ; Dong L; Schutkowski M; Reimer U; Alessi DR
J Biol Chem; 2002 Aug; 277(31):27839-49. PubMed ID: 12023960
[TBL] [Abstract][Full Text] [Related]
2. Identification of the NIMA family kinases NEK6/7 as regulators of the p70 ribosomal S6 kinase.
Belham C; Comb MJ; Avruch J
Curr Biol; 2001 Aug; 11(15):1155-67. PubMed ID: 11516946
[TBL] [Abstract][Full Text] [Related]
3. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
García-Martínez JM; Alessi DR
Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
[TBL] [Abstract][Full Text] [Related]
4. In vivo role of the phosphate groove of PDK1 defined by knockin mutation.
Collins BJ; Deak M; Murray-Tait V; Storey KG; Alessi DR
J Cell Sci; 2005 Nov; 118(Pt 21):5023-34. PubMed ID: 16219676
[TBL] [Abstract][Full Text] [Related]
5. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.
Biondi RM; Kieloch A; Currie RA; Deak M; Alessi DR
EMBO J; 2001 Aug; 20(16):4380-90. PubMed ID: 11500365
[TBL] [Abstract][Full Text] [Related]
6. A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.
Frödin M; Antal TL; Dümmler BA; Jensen CJ; Deak M; Gammeltoft S; Biondi RM
EMBO J; 2002 Oct; 21(20):5396-407. PubMed ID: 12374740
[TBL] [Abstract][Full Text] [Related]
7. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells.
Williams MR; Arthur JS; Balendran A; van der Kaay J; Poli V; Cohen P; Alessi DR
Curr Biol; 2000 Apr; 10(8):439-48. PubMed ID: 10801415
[TBL] [Abstract][Full Text] [Related]
8. A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases.
Belham C; Roig J; Caldwell JA; Aoyama Y; Kemp BE; Comb M; Avruch J
J Biol Chem; 2003 Sep; 278(37):34897-909. PubMed ID: 12840024
[TBL] [Abstract][Full Text] [Related]
9. Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase.
Chrestensen CA; Sturgill TW
J Biol Chem; 2002 Aug; 277(31):27733-41. PubMed ID: 12016217
[TBL] [Abstract][Full Text] [Related]
10. Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252.
Balendran A; Currie R; Armstrong CG; Avruch J; Alessi DR
J Biol Chem; 1999 Dec; 274(52):37400-6. PubMed ID: 10601311
[TBL] [Abstract][Full Text] [Related]
11. Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.
Kobayashi T; Deak M; Morrice N; Cohen P
Biochem J; 1999 Nov; 344 Pt 1(Pt 1):189-97. PubMed ID: 10548550
[TBL] [Abstract][Full Text] [Related]
12. Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1).
Keshwani MM; von Daake S; Newton AC; Harris TK; Taylor SS
J Biol Chem; 2011 Jul; 286(26):23552-8. PubMed ID: 21561857
[TBL] [Abstract][Full Text] [Related]
13. WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate.
Vitari AC; Deak M; Collins BJ; Morrice N; Prescott AR; Phelan A; Humphreys S; Alessi DR
Biochem J; 2004 Feb; 378(Pt 1):257-68. PubMed ID: 14611643
[TBL] [Abstract][Full Text] [Related]
14. A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1.
Balendran A; Biondi RM; Cheung PC; Casamayor A; Deak M; Alessi DR
J Biol Chem; 2000 Jul; 275(27):20806-13. PubMed ID: 10764742
[TBL] [Abstract][Full Text] [Related]
15. Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site.
Ali SM; Sabatini DM
J Biol Chem; 2005 May; 280(20):19445-8. PubMed ID: 15809305
[TBL] [Abstract][Full Text] [Related]
16. An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase.
Mukhopadhyay NK; Price DJ; Kyriakis JM; Pelech S; Sanghera J; Avruch J
J Biol Chem; 1992 Feb; 267(5):3325-35. PubMed ID: 1737788
[TBL] [Abstract][Full Text] [Related]
17. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2.
Kobayashi T; Cohen P
Biochem J; 1999 Apr; 339 ( Pt 2)(Pt 2):319-28. PubMed ID: 10191262
[TBL] [Abstract][Full Text] [Related]
18. Differential control of the NIMA-related kinases, Nek6 and Nek7, by serum stimulation.
Minoguchi S; Minoguchi M; Yoshimura A
Biochem Biophys Res Commun; 2003 Feb; 301(4):899-906. PubMed ID: 12589797
[TBL] [Abstract][Full Text] [Related]
19. Determinants of multi-site phosphorylation of peptide analogues of ribosomal protein S6 by novel protease-activated protein kinases.
Wettenhall RE; Gabrielli B; Morrice N; Bozinova L; Kemp BE; Stapleton D
Pept Res; 1991; 4(3):158-70. PubMed ID: 1823186
[TBL] [Abstract][Full Text] [Related]
20. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).
Brunet A; Park J; Tran H; Hu LS; Hemmings BA; Greenberg ME
Mol Cell Biol; 2001 Feb; 21(3):952-65. PubMed ID: 11154281
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
