157 related articles for article (PubMed ID: 12031664)
1. The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase.
Beck BJ; Yoon YJ; Reynolds KA; Sherman DH
Chem Biol; 2002 May; 9(5):575-83. PubMed ID: 12031664
[TBL] [Abstract][Full Text] [Related]
2. Mechanisms of molecular recognition in the pikromycin polyketide synthase.
Chen S; Xue Y; Sherman DH; Reynolds KA
Chem Biol; 2000 Dec; 7(12):907-18. PubMed ID: 11137814
[TBL] [Abstract][Full Text] [Related]
3. An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis.
Kim BS; Cropp TA; Florova G; Lindsay Y; Sherman DH; Reynolds KA
Biochemistry; 2002 Sep; 41(35):10827-33. PubMed ID: 12196022
[TBL] [Abstract][Full Text] [Related]
4. Alternative modular polyketide synthase expression controls macrolactone structure.
Xue Y; Sherman DH
Nature; 2000 Feb; 403(6769):571-5. PubMed ID: 10676969
[TBL] [Abstract][Full Text] [Related]
5. Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase.
Kittendorf JD; Beck BJ; Buchholz TJ; Seufert W; Sherman DH
Chem Biol; 2007 Aug; 14(8):944-54. PubMed ID: 17719493
[TBL] [Abstract][Full Text] [Related]
6. Iterative chain elongation by a pikromycin monomodular polyketide synthase.
Beck BJ; Aldrich CC; Fecik RA; Reynolds KA; Sherman DH
J Am Chem Soc; 2003 Apr; 125(16):4682-3. PubMed ID: 12696866
[TBL] [Abstract][Full Text] [Related]
7. Elucidating the mechanism of chain termination switching in the picromycin/methymycin polyketide synthase.
Tang L; Fu H; Betlach MC; McDaniel R
Chem Biol; 1999 Aug; 6(8):553-8. PubMed ID: 10421766
[TBL] [Abstract][Full Text] [Related]
8. Substrate recognition and channeling of monomodules from the pikromycin polyketide synthase.
Beck BJ; Aldrich CC; Fecik RA; Reynolds KA; Sherman DH
J Am Chem Soc; 2003 Oct; 125(41):12551-7. PubMed ID: 14531700
[TBL] [Abstract][Full Text] [Related]
9. Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae.
Yoon YJ; Beck BJ; Kim BS; Kang HY; Reynolds KA; Sherman DH
Chem Biol; 2002 Feb; 9(2):203-14. PubMed ID: 11880035
[TBL] [Abstract][Full Text] [Related]
10. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae.
Jung WS; Lee SK; Hong JS; Park SR; Jeong SJ; Han AR; Sohng JK; Kim BG; Choi CY; Sherman DH; Yoon YJ
Appl Microbiol Biotechnol; 2006 Oct; 72(4):763-9. PubMed ID: 16493552
[TBL] [Abstract][Full Text] [Related]
11. Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide.
Aldrich CC; Venkatraman L; Sherman DH; Fecik RA
J Am Chem Soc; 2005 Jun; 127(25):8910-1. PubMed ID: 15969542
[TBL] [Abstract][Full Text] [Related]
12. Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides.
Xue Y; Wilson D; Sherman DH
Gene; 2000 Mar; 245(1):203-11. PubMed ID: 10713461
[TBL] [Abstract][Full Text] [Related]
13. Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthases.
Tang L; Fu H; McDaniel R
Chem Biol; 2000 Feb; 7(2):77-84. PubMed ID: 10662693
[TBL] [Abstract][Full Text] [Related]
14. Functional dissection of a multimodular polypeptide of the pikromycin polyketide synthase into monomodules by using a matched pair of heterologous docking domains.
Yan J; Gupta S; Sherman DH; Reynolds KA
Chembiochem; 2009 Jun; 10(9):1537-43. PubMed ID: 19437523
[TBL] [Abstract][Full Text] [Related]
15. Biochemical investigation of pikromycin biosynthesis employing native penta- and hexaketide chain elongation intermediates.
Aldrich CC; Beck BJ; Fecik RA; Sherman DH
J Am Chem Soc; 2005 Jun; 127(23):8441-52. PubMed ID: 15941278
[TBL] [Abstract][Full Text] [Related]
16. The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide.
Chen S; Roberts JB; Xue Y; Sherman DH; Reynolds KA
Gene; 2001 Jan; 263(1-2):255-64. PubMed ID: 11223265
[TBL] [Abstract][Full Text] [Related]
17. A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.
Xue Y; Zhao L; Liu HW; Sherman DH
Proc Natl Acad Sci U S A; 1998 Oct; 95(21):12111-6. PubMed ID: 9770448
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases.
Mortison JD; Kittendorf JD; Sherman DH
J Am Chem Soc; 2009 Nov; 131(43):15784-93. PubMed ID: 19810731
[TBL] [Abstract][Full Text] [Related]
19. Generation of novel pikromycin antibiotic products through mutasynthesis.
Gupta S; Lakshmanan V; Kim BS; Fecik R; Reynolds KA
Chembiochem; 2008 Jul; 9(10):1609-16. PubMed ID: 18512859
[TBL] [Abstract][Full Text] [Related]
20. Total synthesis of 10-deoxymethynolide and narbonolide.
Xuan R; Oh HS; Lee Y; Kang HY
J Org Chem; 2008 Feb; 73(4):1456-61. PubMed ID: 18205385
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]