76 related articles for article (PubMed ID: 12031672)
1. Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome.
Groll M; Nazif T; Huber R; Bogyo M
Chem Biol; 2002 May; 9(5):655-62. PubMed ID: 12031672
[TBL] [Abstract][Full Text] [Related]
2. Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation.
Arendt CS; Hochstrasser M
Proc Natl Acad Sci U S A; 1997 Jul; 94(14):7156-61. PubMed ID: 9207060
[TBL] [Abstract][Full Text] [Related]
3. Keepers at the final gates: regulatory complexes and gating of the proteasome channel.
Bajorek M; Glickman MH
Cell Mol Life Sci; 2004 Jul; 61(13):1579-88. PubMed ID: 15224182
[TBL] [Abstract][Full Text] [Related]
4. Simplified synthetic TMC-95A/B analogues retain the potency of proteasome inhibitory activity.
Yang ZQ; Kwok BH; Lin S; Koldobskiy MA; Crews CM; Danishefsky SJ
Chembiochem; 2003 Jun; 4(6):508-13. PubMed ID: 12794861
[TBL] [Abstract][Full Text] [Related]
5. The ultimate nanoscale mincer: assembly, structure and active sites of the 20S proteasome core.
Heinemeyer W; Ramos PC; Dohmen RJ
Cell Mol Life Sci; 2004 Jul; 61(13):1562-78. PubMed ID: 15224181
[TBL] [Abstract][Full Text] [Related]
6. Lysine 188 substitutions convert the pattern of proteasome activation by REGgamma to that of REGs alpha and beta.
Li J; Gao X; Ortega J; Nazif T; Joss L; Bogyo M; Steven AC; Rechsteiner M
EMBO J; 2001 Jul; 20(13):3359-69. PubMed ID: 11432824
[TBL] [Abstract][Full Text] [Related]
7. Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase from Bacillus anthracis.
Morgunova E; Illarionov B; Saller S; Popov A; Sambaiah T; Bacher A; Cushman M; Fischer M; Ladenstein R
Acta Crystallogr D Biol Crystallogr; 2010 Sep; 66(Pt 9):1001-11. PubMed ID: 20823551
[TBL] [Abstract][Full Text] [Related]
8. Analysis of bortezomib inhibitor docked within the catalytic subunits of the Plasmodium falciparum 20S proteasome.
Sridhar S; Bhat G; Guruprasad K
Springerplus; 2013; 2():566. PubMed ID: 24255860
[TBL] [Abstract][Full Text] [Related]
9. Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core.
da Fonseca PC; Morris EP
Nat Commun; 2015 Jul; 6():7573. PubMed ID: 26133119
[TBL] [Abstract][Full Text] [Related]
10. Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.
Ramirez YA; Adler TB; Altmann E; Klemm T; Tiesmeyer C; Sauer F; Kathman SG; Statsyuk AV; Sotriffer C; Kisker C
ChemMedChem; 2018 Oct; 13(19):2014-2023. PubMed ID: 30028574
[TBL] [Abstract][Full Text] [Related]
11. 20S proteasome hydrolysis of LLVY substrates to determine preferences for moieties in its primed substrate channel.
Muli CS; Trader DJ
Bioorg Med Chem Lett; 2023 Apr; 85():129233. PubMed ID: 36905968
[TBL] [Abstract][Full Text] [Related]
12. Structural elucidation of recombinant
Silhan J; Fajtova P; Bartosova J; Hurysz BM; Almaliti J; Miyamoto Y; Eckmann L; Gerwick WH; O'Donoghue AJ; Boura E
bioRxiv; 2023 Aug; ():. PubMed ID: 37645851
[TBL] [Abstract][Full Text] [Related]
13. Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome.
Götz MG; Godwin K; Price R; Dorn R; Merrill-Steskal G; Klemmer W; Hansen H; Produturi G; Rocha M; Palmer M; Molacek L; Strater Z; Groll M
ACS Med Chem Lett; 2024 Apr; 15(4):533-539. PubMed ID: 38628795
[TBL] [Abstract][Full Text] [Related]
14. Mechanism of autocatalytic activation during proteasome assembly.
Velez B; Walsh RM; Rawson S; Razi A; Adams L; Perez EF; Jiao F; Blickling M; Rajakumar T; Fung D; Huang L; Hanna J
Nat Struct Mol Biol; 2024 Apr; ():. PubMed ID: 38600323
[TBL] [Abstract][Full Text] [Related]
15. Rational design of proteasome inhibitors based on the structure of the endogenous inhibitor PI31/Fub1.
Velez B; Razi A; Hubbard RD; Walsh R; Rawson S; Tian G; Finley D; Hanna J
Proc Natl Acad Sci U S A; 2023 Dec; 120(51):e2308417120. PubMed ID: 38091293
[TBL] [Abstract][Full Text] [Related]
16. Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines.
Ielo L; Patamia V; Citarella A; Efferth T; Shahhamzehei N; Schirmeister T; Stagno C; Langer T; Rescifina A; Micale N; Pace V
Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293216
[TBL] [Abstract][Full Text] [Related]
17. Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance.
Leonardo-Sousa C; Carvalho AN; Guedes RA; Fernandes PMP; Aniceto N; Salvador JAR; Gama MJ; Guedes RC
Molecules; 2022 Mar; 27(7):. PubMed ID: 35408601
[TBL] [Abstract][Full Text] [Related]
18. Structural Insights into Substrate Recognition and Processing by the 20S Proteasome.
Sahu I; Glickman MH
Biomolecules; 2021 Jan; 11(2):. PubMed ID: 33498876
[TBL] [Abstract][Full Text] [Related]
19. Exploring the Proteolysis Mechanism of the Proteasomes.
Saha A; Oanca G; Mondal D; Warshel A
J Phys Chem B; 2020 Jul; 124(27):5626-5635. PubMed ID: 32498514
[TBL] [Abstract][Full Text] [Related]
20. The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges.
Tundo GR; Sbardella D; Santoro AM; Coletta A; Oddone F; Grasso G; Milardi D; Lacal PM; Marini S; Purrello R; Graziani G; Coletta M
Pharmacol Ther; 2020 Sep; 213():107579. PubMed ID: 32442437
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]