256 related articles for article (PubMed ID: 12031957)
1. A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.
Brennan L; Shine A; Hewage C; Malthouse JP; Brindle KM; McClenaghan N; Flatt PR; Newsholme P
Diabetes; 2002 Jun; 51(6):1714-21. PubMed ID: 12031957
[TBL] [Abstract][Full Text] [Related]
2. A comparative study of amino acid consumption by rat islet cells and the clonal beta-cell line BRIN-BD11 - the functional significance of L-alanine.
Dixon G; Nolan J; McClenaghan N; Flatt PR; Newsholme P
J Endocrinol; 2003 Dec; 179(3):447-54. PubMed ID: 14656214
[TBL] [Abstract][Full Text] [Related]
3. 13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line.
Brennan L; Corless M; Hewage C; Malthouse JP; McClenaghan NH; Flatt PR; Newsholme P
Diabetologia; 2003 Nov; 46(11):1512-21. PubMed ID: 12955201
[TBL] [Abstract][Full Text] [Related]
4. Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
McClenaghan NH; Barnett CR; O'Harte FP; Flatt PR
J Endocrinol; 1996 Dec; 151(3):349-57. PubMed ID: 8994380
[TBL] [Abstract][Full Text] [Related]
5. Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic beta-cell line.
Kiely A; McClenaghan NH; Flatt PR; Newsholme P
J Endocrinol; 2007 Oct; 195(1):113-23. PubMed ID: 17911403
[TBL] [Abstract][Full Text] [Related]
6. Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic beta-cell insulin secretion, growth and functional integrity.
Dixon G; Nolan J; McClenaghan NH; Flatt PR; Newsholme P
Clin Sci (Lond); 2004 Feb; 106(2):191-9. PubMed ID: 14561212
[TBL] [Abstract][Full Text] [Related]
7. The stimulus-secretion coupling of amino acid-induced insulin release. Insulinotropic action of L-alanine.
Sener A; Malaisse WJ
Biochim Biophys Acta; 2002 Oct; 1573(1):100-4. PubMed ID: 12383948
[TBL] [Abstract][Full Text] [Related]
8. Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.
Patterson S; Flatt PR; Brennan L; Newsholme P; McClenaghan NH
J Endocrinol; 2006 May; 189(2):301-10. PubMed ID: 16648297
[TBL] [Abstract][Full Text] [Related]
9. Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.
Carobbio S; Ishihara H; Fernandez-Pascual S; Bartley C; Martin-Del-Rio R; Maechler P
Diabetologia; 2004 Feb; 47(2):266-76. PubMed ID: 14689183
[TBL] [Abstract][Full Text] [Related]
10. L-arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge.
Krause MS; McClenaghan NH; Flatt PR; de Bittencourt PI; Murphy C; Newsholme P
J Endocrinol; 2011 Oct; 211(1):87-97. PubMed ID: 21784771
[TBL] [Abstract][Full Text] [Related]
11. 13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells.
Cline GW; Lepine RL; Papas KK; Kibbey RG; Shulman GI
J Biol Chem; 2004 Oct; 279(43):44370-5. PubMed ID: 15304488
[TBL] [Abstract][Full Text] [Related]
12. Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart.
Lloyd S; Brocks C; Chatham JC
Am J Physiol Heart Circ Physiol; 2003 Jul; 285(1):H163-72. PubMed ID: 12793977
[TBL] [Abstract][Full Text] [Related]
13. 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS).
Lu D; Mulder H; Zhao P; Burgess SC; Jensen MV; Kamzolova S; Newgard CB; Sherry AD
Proc Natl Acad Sci U S A; 2002 Mar; 99(5):2708-13. PubMed ID: 11880625
[TBL] [Abstract][Full Text] [Related]
14. Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion.
Ainscow EK; Zhao C; Rutter GA
Diabetes; 2000 Jul; 49(7):1149-55. PubMed ID: 10909972
[TBL] [Abstract][Full Text] [Related]
15. Characterization of a novel glucose-responsive insulin-secreting cell line, BRIN-BD11, produced by electrofusion.
McClenaghan NH; Barnett CR; Ah-Sing E; Abdel-Wahab YH; O'Harte FP; Yoon TW; Swanston-Flatt SK; Flatt PR
Diabetes; 1996 Aug; 45(8):1132-40. PubMed ID: 8690162
[TBL] [Abstract][Full Text] [Related]
16. Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets.
Casimir M; Rubi B; Frigerio F; Chaffard G; Maechler P
Biochem J; 2009 Dec; 424(3):459-66. PubMed ID: 19764902
[TBL] [Abstract][Full Text] [Related]
17. Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.
Fransson U; Rosengren AH; Schuit FC; Renström E; Mulder H
Diabetologia; 2006 Jul; 49(7):1578-86. PubMed ID: 16752176
[TBL] [Abstract][Full Text] [Related]
18. Mathematical model of metabolism and electrophysiology of amino acid and glucose stimulated insulin secretion: in vitro validation using a β-cell line.
Salvucci M; Neufeld Z; Newsholme P
PLoS One; 2013; 8(3):e52611. PubMed ID: 23520444
[TBL] [Abstract][Full Text] [Related]
19. Culture and function of electrofusion-derived clonal insulin-secreting cells immobilized on solid and macroporous microcarrier beads.
Hamid M; McCluskey JT; McClenaghan NH; Flatt PR
Biosci Rep; 2000 Jun; 20(3):167-76. PubMed ID: 11095116
[TBL] [Abstract][Full Text] [Related]
20. L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis.
Cunningham GA; McClenaghan NH; Flatt PR; Newsholme P
Clin Sci (Lond); 2005 Nov; 109(5):447-55. PubMed ID: 16045439
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
