BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

512 related articles for article (PubMed ID: 12032158)

  • 1. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
    Treins C; Giorgetti-Peraldi S; Murdaca J; Semenza GL; Van Obberghen E
    J Biol Chem; 2002 Aug; 277(31):27975-81. PubMed ID: 12032158
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
    Laughner E; Taghavi P; Chiles K; Mahon PC; Semenza GL
    Mol Cell Biol; 2001 Jun; 21(12):3995-4004. PubMed ID: 11359907
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF.
    Poulaki V; Qin W; Joussen AM; Hurlbut P; Wiegand SJ; Rudge J; Yancopoulos GD; Adamis AP
    J Clin Invest; 2002 Mar; 109(6):805-15. PubMed ID: 11901189
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.
    Mayerhofer M; Valent P; Sperr WR; Griffin JD; Sillaber C
    Blood; 2002 Nov; 100(10):3767-75. PubMed ID: 12393646
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway.
    Kim CH; Cho YS; Chun YS; Park JW; Kim MS
    Circ Res; 2002 Feb; 90(2):E25-33. PubMed ID: 11834720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
    Mabjeesh NJ; Willard MT; Frederickson CE; Zhong H; Simons JW
    Clin Cancer Res; 2003 Jul; 9(7):2416-25. PubMed ID: 12855613
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Vanadate-induced expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species.
    Gao N; Ding M; Zheng JZ; Zhang Z; Leonard SS; Liu KJ; Shi X; Jiang BH
    J Biol Chem; 2002 Aug; 277(35):31963-71. PubMed ID: 12070140
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
    Gao N; Nester RA; Sarkar MA
    Toxicol Appl Pharmacol; 2004 Apr; 196(1):124-35. PubMed ID: 15050414
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
    Jiang BH; Jiang G; Zheng JZ; Lu Z; Hunter T; Vogt PK
    Cell Growth Differ; 2001 Jul; 12(7):363-9. PubMed ID: 11457733
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I.
    Treins C; Giorgetti-Peraldi S; Murdaca J; Monthouël-Kartmann MN; Van Obberghen E
    Mol Endocrinol; 2005 May; 19(5):1304-17. PubMed ID: 15695372
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
    Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
    [TBL] [Abstract][Full Text] [Related]  

  • 13. VEGF production by primary human renal proximal tubular cells: requirement of HIF-1, PI3-kinase and MAPKK-1 signaling.
    Hellwig-Bürgel T; Stiehl DP; Katschinski DM; Marxsen J; Kreft B; Jelkmann W
    Cell Physiol Biochem; 2005; 15(1-4):99-108. PubMed ID: 15665520
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite.
    Duyndam MC; Hulscher ST; van der Wall E; Pinedo HM; Boven E
    J Biol Chem; 2003 Feb; 278(9):6885-95. PubMed ID: 12482858
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of vascular endothelial growth factor expression by advanced glycation end products.
    Treins C; Giorgetti-Peraldi S; Murdaca J; Van Obberghen E
    J Biol Chem; 2001 Nov; 276(47):43836-41. PubMed ID: 11571295
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway.
    Yoo YG; Oh SH; Park ES; Cho H; Lee N; Park H; Kim DK; Yu DY; Seong JK; Lee MO
    J Biol Chem; 2003 Oct; 278(40):39076-84. PubMed ID: 12855680
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation.
    Alam H; Maizels ET; Park Y; Ghaey S; Feiger ZJ; Chandel NS; Hunzicker-Dunn M
    J Biol Chem; 2004 May; 279(19):19431-40. PubMed ID: 14982927
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
    Shi YH; Wang YX; Bingle L; Gong LH; Heng WJ; Li Y; Fang WG
    J Pathol; 2005 Mar; 205(4):530-6. PubMed ID: 15714461
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways.
    Miele C; Rochford JJ; Filippa N; Giorgetti-Peraldi S; Van Obberghen E
    J Biol Chem; 2000 Jul; 275(28):21695-702. PubMed ID: 10777488
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase.
    Görlach A; Diebold I; Schini-Kerth VB; Berchner-Pfannschmidt U; Roth U; Brandes RP; Kietzmann T; Busse R
    Circ Res; 2001 Jul; 89(1):47-54. PubMed ID: 11440977
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.