166 related articles for article (PubMed ID: 12034349)
21. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
Cui JY; Klaassen CD
Biochim Biophys Acta; 2016 Sep; 1859(9):1198-1217. PubMed ID: 27113289
[TBL] [Abstract][Full Text] [Related]
22. The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice.
Shizu R; Ishimura M; Nobusawa S; Hosaka T; Sasaki T; Kakizaki S; Yoshinari K
Arch Toxicol; 2021 Mar; 95(3):1089-1102. PubMed ID: 33398415
[TBL] [Abstract][Full Text] [Related]
23. Effect of lipopolysaccharide on the xenobiotic-induced expression and activity of hepatic cytochrome P450 in mice.
Moriya N; Kataoka H; Fujino H; Nishikawa J; Kugawa F
Biol Pharm Bull; 2012; 35(4):473-80. PubMed ID: 22466549
[TBL] [Abstract][Full Text] [Related]
24. Induction of cytochrome P-450 by glucocorticoids in rat liver. II. Evidence that glucocorticoids regulate induction of cytochrome P-450 by a nonclassical receptor mechanism.
Schuetz EG; Guzelian PS
J Biol Chem; 1984 Feb; 259(3):2007-12. PubMed ID: 6141168
[TBL] [Abstract][Full Text] [Related]
25. Simultaneous substitution of phenylalanine-305 and aspartate-318 of rat pregnane X receptor with the corresponding human residues abolishes the ability to transactivate the CYP3A23 promoter.
Song X; Li Y; Liu J; Mukundan M; Yan B
J Pharmacol Exp Ther; 2005 Feb; 312(2):571-82. PubMed ID: 15367577
[TBL] [Abstract][Full Text] [Related]
26. Activation of pregnane X receptor by pregnenolone 16 α-carbonitrile prevents high-fat diet-induced obesity in AKR/J mice.
Ma Y; Liu D
PLoS One; 2012; 7(6):e38734. PubMed ID: 22723881
[TBL] [Abstract][Full Text] [Related]
27. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
[TBL] [Abstract][Full Text] [Related]
28. Effect of pregnane X receptor ligand on pharmacokinetics of substrates of organic cation transporter Oct1 in rats.
Maeda T; Oyabu M; Yotsumoto T; Higashi R; Nagata K; Yamazoe Y; Tamai I
Drug Metab Dispos; 2007 Sep; 35(9):1580-6. PubMed ID: 17553914
[TBL] [Abstract][Full Text] [Related]
29. Glucocorticoid receptor-independent transcriptional induction of cytochrome P450 3A1 by metyrapone and its potentiation by glucocorticoid.
Wright MC; Wang XJ; Pimenta M; Ribeiro V; Paine AJ; Lechner MC
Mol Pharmacol; 1996 Oct; 50(4):856-63. PubMed ID: 8863830
[TBL] [Abstract][Full Text] [Related]
30. Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors.
Huss JM; Kasper CB
Mol Pharmacol; 2000 Jul; 58(1):48-57. PubMed ID: 10860926
[TBL] [Abstract][Full Text] [Related]
31. Pregnane X receptor-agonists down-regulate hepatic ATP-binding cassette transporter A1 and scavenger receptor class B type I.
Sporstøl M; Tapia G; Malerød L; Mousavi SA; Berg T
Biochem Biophys Res Commun; 2005 Jun; 331(4):1533-41. PubMed ID: 15883047
[TBL] [Abstract][Full Text] [Related]
32. Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes.
Kocarek TA; Shenoy SD; Mercer-Haines NA; Runge-Morris M
J Pharmacol Toxicol Methods; 2002; 47(3):177-87. PubMed ID: 12628309
[TBL] [Abstract][Full Text] [Related]
33. Pregnenolone 16α-carbonitrile ameliorates concanavalin A-induced liver injury in mice independent of the nuclear receptor PXR activation.
Kodama S; Shimura T; Kuribayashi H; Abe T; Yoshinari K
Toxicol Lett; 2017 Apr; 271():58-65. PubMed ID: 28237809
[TBL] [Abstract][Full Text] [Related]
34. Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia.
Pascussi JM; Robert A; Nguyen M; Walrant-Debray O; Garabedian M; Martin P; Pineau T; Saric J; Navarro F; Maurel P; Vilarem MJ
J Clin Invest; 2005 Jan; 115(1):177-86. PubMed ID: 15630458
[TBL] [Abstract][Full Text] [Related]
35. Nuclear receptor, pregname X receptor, is required for induction of UDP-glucuronosyltranferases in mouse liver by pregnenolone-16 alpha-carbonitrile.
Chen C; Staudinger JL; Klaassen CD
Drug Metab Dispos; 2003 Jul; 31(7):908-15. PubMed ID: 12814968
[TBL] [Abstract][Full Text] [Related]
36. Effects of dexamethasone on aryl (SULT1A1)- and hydroxysteroid (SULT2A1)-sulfotransferase gene expression in primary cultured human hepatocytes.
Duanmu Z; Locke D; Smigelski J; Wu W; Dahn MS; Falany CN; Kocarek TA; Runge-Morris M
Drug Metab Dispos; 2002 Sep; 30(9):997-1004. PubMed ID: 12167565
[TBL] [Abstract][Full Text] [Related]
37. Gut Microbiota Affects Mouse Pregnane X Receptor Agonist Pregnenolone 16α-Carbonitrile-Induced Hepatomegaly by Regulating Pregnane X Receptor and Yes-Associated Protein Activation.
Wu T; Li L; Zhou W; Bi G; Jiang X; Guo M; Yang X; Fang J; Pang J; Fan S; Bi H
Drug Metab Dispos; 2024 Jun; 52(7):597-605. PubMed ID: 38697851
[TBL] [Abstract][Full Text] [Related]
38. Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation.
Gonzalez FJ; Song BJ; Hardwick JP
Mol Cell Biol; 1986 Aug; 6(8):2969-76. PubMed ID: 3785219
[TBL] [Abstract][Full Text] [Related]
39. Effect of Pregnenolone 16α-Carbonitrile on the Expression of P-Glycoprotein in the Intestine, Brain and Liver of Mice.
Yamasaki Y; Kobayashi K; Chiba K
Biol Pharm Bull; 2018; 41(6):972-977. PubMed ID: 29863087
[TBL] [Abstract][Full Text] [Related]
40. Characterization of DNA-binding proteins required for glucocorticoid induction of CYP3A23.
Quattrochi LC; Yockey CB; Barwick JL; Guzelian PS
Arch Biochem Biophys; 1998 Jan; 349(2):251-60. PubMed ID: 9448712
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
