These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

321 related articles for article (PubMed ID: 12034742)

  • 1. Reversible manipulation of telomerase expression and telomere length. Implications for the ionizing radiation response and replicative senescence of human cells.
    Rubio MA; Kim SH; Campisi J
    J Biol Chem; 2002 Aug; 277(32):28609-17. PubMed ID: 12034742
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells.
    Jones KR; Elmore LW; Jackson-Cook C; Demasters G; Povirk LF; Holt SE; Gewirtz DA
    Int J Radiat Biol; 2005 Jun; 81(6):445-58. PubMed ID: 16308915
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Strict control of telomerase activation using Cre-mediated inversion.
    Ungrin MD; Harrington L
    BMC Biotechnol; 2006 Feb; 6():10. PubMed ID: 16504006
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Haploinsufficiency of hTERT leads to telomere dysfunction and radiosensitivity in human cancer cells.
    Hauguel T; Bunz F
    Cancer Biol Ther; 2003; 2(6):679-84. PubMed ID: 14688476
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase.
    Ouellette MM; Liao M; Herbert BS; Johnson M; Holt SE; Liss HS; Shay JW; Wright WE
    J Biol Chem; 2000 Apr; 275(14):10072-6. PubMed ID: 10744686
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres.
    Munro J; Steeghs K; Morrison V; Ireland H; Parkinson EK
    Oncogene; 2001 Jun; 20(27):3541-52. PubMed ID: 11429701
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.
    MacKenzie KL; Franco S; May C; Sadelain M; Moore MA
    Exp Cell Res; 2000 Sep; 259(2):336-50. PubMed ID: 10964501
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Extension of life-span by introduction of telomerase into normal human cells.
    Bodnar AG; Ouellette M; Frolkis M; Holt SE; Chiu CP; Morin GB; Harley CB; Shay JW; Lichtsteiner S; Wright WE
    Science; 1998 Jan; 279(5349):349-52. PubMed ID: 9454332
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The implication of telomerase activity and telomere stability for replicative aging and cellular immortality (Review).
    Engelhardt M; Martens UM
    Oncol Rep; 1998; 5(5):1043-52. PubMed ID: 9683806
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Telomerase immortalization of human myometrial cells.
    Condon J; Yin S; Mayhew B; Word RA; Wright WE; Shay JW; Rainey WE
    Biol Reprod; 2002 Aug; 67(2):506-14. PubMed ID: 12135889
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential.
    Rufer N; Migliaccio M; Antonchuk J; Humphries RK; Roosnek E; Lansdorp PM
    Blood; 2001 Aug; 98(3):597-603. PubMed ID: 11468156
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development.
    Waki K; Anno K; Ono T; Ide T; Chayama K; Tahara H
    Cancer Sci; 2010 Jul; 101(7):1678-85. PubMed ID: 20456367
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Telomere shortening and decline in replicative potential as a function of donor age in human adrenocortical cells.
    Yang L; Suwa T; Wright WE; Shay JW; Hornsby PJ
    Mech Ageing Dev; 2001 Oct; 122(15):1685-94. PubMed ID: 11557273
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human telomerase reverse transcriptase immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway.
    Wang J; Feng H; Huang XQ; Xiang H; Mao YW; Liu JP; Yan Q; Liu WB; Liu Y; Deng M; Gong L; Sun S; Luo C; Liu SJ; Zhang XJ; Liu Y; Li DW
    J Biol Chem; 2005 Jun; 280(24):22776-87. PubMed ID: 15849192
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence that high telomerase activity may induce a senescent-like growth arrest in human fibroblasts.
    Gorbunova V; Seluanov A; Pereira-Smith OM
    J Biol Chem; 2003 Feb; 278(9):7692-8. PubMed ID: 12496279
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Senescence occurs with hTERT repression and limited telomere shortening in human oral keratinocytes cultured with feeder cells.
    Kang MK; Kameta A; Shin KH; Baluda MA; Park NH
    J Cell Physiol; 2004 Jun; 199(3):364-70. PubMed ID: 15095283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres.
    Goodwin EC; DiMaio D
    Cell Growth Differ; 2001 Nov; 12(11):525-34. PubMed ID: 11714633
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination.
    Gomes NM; Ryder OA; Houck ML; Charter SJ; Walker W; Forsyth NR; Austad SN; Venditti C; Pagel M; Shay JW; Wright WE
    Aging Cell; 2011 Oct; 10(5):761-8. PubMed ID: 21518243
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proliferation of adult human bronchial epithelial cells without a telomere maintenance mechanism for over 200 population doublings.
    Peters-Hall JR; Min J; Tedone E; Sho S; Siteni S; Mender I; Shay JW
    FASEB J; 2020 Jan; 34(1):386-398. PubMed ID: 31914653
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Catalytically active human telomerase mutants with allele-specific biological properties.
    Kim M; Xu L; Blackburn EH
    Exp Cell Res; 2003 Aug; 288(2):277-87. PubMed ID: 12915119
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.