BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 12042666)

  • 1. Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 and UGT1A8*3.
    Huang YH; Galijatovic A; Nguyen N; Geske D; Beaton D; Green J; Green M; Peters WH; Tukey RH
    Pharmacogenetics; 2002 Jun; 12(4):287-97. PubMed ID: 12042666
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8.
    Strassburg CP; Manns MP; Tukey RH
    J Biol Chem; 1998 Apr; 273(15):8719-26. PubMed ID: 9535849
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8.
    Cheng Z; Radominska-Pandya A; Tephly TR
    Arch Biochem Biophys; 1998 Aug; 356(2):301-5. PubMed ID: 9705221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.
    Gregory PA; Gardner-Stephen DA; Lewinsky RH; Duncliffe KN; Mackenzie PI
    J Biol Chem; 2003 Sep; 278(38):36107-14. PubMed ID: 12847094
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coordinate regulation of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 genes by hepatocyte nuclear factor 1alpha and the caudal-related homeodomain protein 2.
    Gregory PA; Lewinsky RH; Gardner-Stephen DA; Mackenzie PI
    Mol Pharmacol; 2004 Apr; 65(4):953-63. PubMed ID: 15044625
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altered coding for a strictly conserved di-glycine in the major bilirubin UDP-glucuronosyltransferase of a Crigler-Najjar type I patient.
    Ciotti M; Yeatman MT; Sokol RJ; Owens IS
    J Biol Chem; 1995 Feb; 270(7):3284-91. PubMed ID: 7852413
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha.
    Barbier O; Girard H; Inoue Y; Duez H; Villeneuve L; Kamiya A; Fruchart JC; Guillemette C; Gonzalez FJ; Staels B
    Mol Pharmacol; 2005 Jan; 67(1):241-9. PubMed ID: 15470081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of Cryptic Donor Splice Sites within the UDP-Glucuronosyltransferase (UGT)1A First-Exon Region Generates Variant Transcripts That Encode UGT1A Proteins with Truncated Aglycone-Binding Domains.
    Hu DG; Marri S; Hulin JA; Ansaar R; Mackenzie PI; McKinnon RA; Meech R
    Drug Metab Dispos; 2024 May; 52(6):526-538. PubMed ID: 38565302
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of UDP-glucuronosyltransferase 1A8 polymorphism on raloxifene glucuronidation.
    Kokawa Y; Kishi N; Jinno H; Tanaka-Kagawa T; Narimatsu S; Hanioka N
    Eur J Pharm Sci; 2013 May; 49(2):199-205. PubMed ID: 23499758
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [The role of NF-E2-related factor 2 in the induction of uridine 5'-diphosphate-glucuronosyltransferase 1A and its isoforms by epigallocatechin gallate in colon cancer cells].
    Yang XY; Zhao WP; Li YQ; Sun ZY; Zhang Y; Guo YT; Yuan JH; Zhu Q; Wang M
    Zhonghua Yi Xue Za Zhi; 2006 Jan; 86(2):82-7. PubMed ID: 16620709
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of UDP-glucuronosyltransferase 1A8 mRNA by 3-methylcholanthene in rat hepatoma cells.
    Leung YK; Ho JW
    Biochem Pharmacol; 2002 Feb; 63(4):767-75. PubMed ID: 11992647
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Key amino acid residues responsible for the differences in substrate specificity of human UDP-glucuronosyltransferase (UGT)1A9 and UGT1A8.
    Fujiwara R; Nakajima M; Yamanaka H; Yokoi T
    Drug Metab Dispos; 2009 Jan; 37(1):41-6. PubMed ID: 18832479
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization and substrate specificity of UGT2B4 (E458): a UDP-glucuronosyltransferase encoded by a polymorphic gene.
    Lévesque E; Beaulieu M; Hum DW; Bélanger A
    Pharmacogenetics; 1999 Apr; 9(2):207-16. PubMed ID: 10376768
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of two single base substitutions in the UGT1 gene locus which abolish bilirubin uridine diphosphate glucuronosyltransferase activity in vitro.
    Erps LT; Ritter JK; Hersh JH; Blossom D; Martin NC; Owens IS
    J Clin Invest; 1994 Feb; 93(2):564-70. PubMed ID: 7906695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In Vitro Study on Influences of UGT1A8 Gene Polymorphisms on Mycophenolate Mofetil Metabolism.
    Zhou Z; Lu Y; Song G; Wang Y; Chen J; Xiao C; Zhong L; Sun X; Peng Z; Wang X
    Exp Clin Transplant; 2018 Aug; 16(4):466-472. PubMed ID: 29025387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of substrate specificities and tissue expression of rat UDP-glucuronosyltransferases UGT1A7 and UGT1A8.
    Webb LJ; Miles KK; Auyeung DJ; Kessler FK; Ritter JK
    Drug Metab Dispos; 2005 Jan; 33(1):77-82. PubMed ID: 15502008
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.
    Cheng Z; Radominska-Pandya A; Tephly TR
    Drug Metab Dispos; 1999 Oct; 27(10):1165-70. PubMed ID: 10497143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the UDP-glucuronosyltransferase 1A locus in lagomorphs: evidence for duplication of the UGT1A6 gene.
    Li Q; Lamb G; Tukey RH
    Mol Pharmacol; 2000 Jul; 58(1):89-97. PubMed ID: 10860930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers.
    Lévesque E; Delage R; Benoit-Biancamano MO; Caron P; Bernard O; Couture F; Guillemette C
    Clin Pharmacol Ther; 2007 Mar; 81(3):392-400. PubMed ID: 17339869
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon.
    Mojarrabi B; Mackenzie PI
    Biochem Biophys Res Commun; 1998 Jun; 247(3):704-9. PubMed ID: 9647757
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.