BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 12049736)

  • 1. Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis.
    Tan M; Jing T; Lan KH; Neal CL; Li P; Lee S; Fang D; Nagata Y; Liu J; Arlinghaus R; Hung MC; Yu D
    Mol Cell; 2002 May; 9(5):993-1004. PubMed ID: 12049736
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 overexpression and with p21Cip1 overexpression.
    Yang W; Klos KS; Zhou X; Yao J; Yang Y; Smith TL; Shi D; Yu D
    Cancer; 2003 Sep; 98(6):1123-30. PubMed ID: 12973835
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells.
    Lee S; Yang W; Lan KH; Sellappan S; Klos K; Hortobagyi G; Hung MC; Yu D
    Cancer Res; 2002 Oct; 62(20):5703-10. PubMed ID: 12384528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase.
    Yu D; Jing T; Liu B; Yao J; Tan M; McDonnell TJ; Hung MC
    Mol Cell; 1998 Nov; 2(5):581-91. PubMed ID: 9844631
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A p21(waf1)-independent pathway for inhibitory phosphorylation of cyclin-dependent kinase p34(cdc2) and concomitant G(2)/M arrest by the chemopreventive flavonoid apigenin.
    McVean M; Weinberg WC; Pelling JC
    Mol Carcinog; 2002 Jan; 33(1):36-43. PubMed ID: 11807956
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells.
    Hawthorne VS; Huang WC; Neal CL; Tseng LM; Hung MC; Yu D
    Mol Cancer Res; 2009 Apr; 7(4):592-600. PubMed ID: 19372587
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptional upregulation and activation of p55Cdc via p34(cdc2) in Taxol-induced apoptosis.
    Makino K; Yu D; Hung MC
    Oncogene; 2001 May; 20(20):2537-43. PubMed ID: 11420663
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea.
    Nishijima H; Nishitani H; Seki T; Nishimoto T
    J Cell Biol; 1997 Sep; 138(5):1105-16. PubMed ID: 9281587
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest.
    Scatena CD; Stewart ZA; Mays D; Tang LJ; Keefer CJ; Leach SD; Pietenpol JA
    J Biol Chem; 1998 Nov; 273(46):30777-84. PubMed ID: 9804855
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of p21(CIP1/Waf1) and activation of p34(cdc2) involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells.
    Hsu SL; Chen MC; Chou YH; Hwang GY; Yin SC
    Exp Cell Res; 1999 Apr; 248(1):87-96. PubMed ID: 10094816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.
    Poon RY; Chau MS; Yamashita K; Hunter T
    Cancer Res; 1997 Nov; 57(22):5168-78. PubMed ID: 9371520
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.
    Bacus SS; Gudkov AV; Lowe M; Lyass L; Yung Y; Komarov AP; Keyomarsi K; Yarden Y; Seger R
    Oncogene; 2001 Jan; 20(2):147-55. PubMed ID: 11313944
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1.
    Chang KL; Kung ML; Chow NH; Su SJ
    Biochem Pharmacol; 2004 Feb; 67(4):717-26. PubMed ID: 14757171
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells.
    Ibrado AM; Kim CN; Bhalla K
    Leukemia; 1998 Dec; 12(12):1930-6. PubMed ID: 9844922
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin.
    Wang S; Huang X; Lee CK; Liu B
    Oncogene; 2010 Jul; 29(29):4225-36. PubMed ID: 20498641
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overexpression of both p185c-erbB2 and p170mdr-1 renders breast cancer cells highly resistant to taxol.
    Yu D; Liu B; Jing T; Sun D; Price JE; Singletary SE; Ibrahim N; Hortobagyi GN; Hung MC
    Oncogene; 1998 Apr; 16(16):2087-94. PubMed ID: 9572489
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance.
    Lu J; Tan M; Huang WC; Li P; Guo H; Tseng LM; Su XH; Yang WT; Treekitkarnmongkol W; Andreeff M; Symmans F; Yu D
    Clin Cancer Res; 2009 Feb; 15(4):1326-34. PubMed ID: 19228734
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.
    Dash BC; El-Deiry WS
    Mol Cell Biol; 2005 Apr; 25(8):3364-87. PubMed ID: 15798220
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells.
    Choi YH; Yoo YH
    Oncol Rep; 2012 Dec; 28(6):2163-9. PubMed ID: 23023313
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Taxol-induced p34cdc2 kinase activation and apoptosis inhibited by 12-O-tetradecanoylphorbol-13-acetate in human breast MCF-7 carcinoma cells.
    Shen SC; Huang TS; Jee SH; Kuo ML
    Cell Growth Differ; 1998 Jan; 9(1):23-9. PubMed ID: 9438385
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.