These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 12051849)

  • 1. Knowledge-based design of reagentless fluorescent biosensors from recombinant antibodies.
    Renard M; Belkadi L; Hugo N; England P; Altschuh D; Bedouelle H
    J Mol Biol; 2002 Apr; 318(2):429-42. PubMed ID: 12051849
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Improving the sensitivity and dynamic range of reagentless fluorescent immunosensors by knowledge-based design.
    Renard M; Bedouelle H
    Biochemistry; 2004 Dec; 43(49):15453-62. PubMed ID: 15581357
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Knowledge-based design of reagentless fluorescent biosensors from a designed ankyrin repeat protein.
    Brient-Litzler E; Plückthun A; Bedouelle H
    Protein Eng Des Sel; 2010 Apr; 23(4):229-41. PubMed ID: 19945965
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen.
    Li Y; Urrutia M; Smith-Gill SJ; Mariuzza RA
    Biochemistry; 2003 Jan; 42(1):11-22. PubMed ID: 12515535
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of the complex of the variable domain of antibody D1.3 and turkey egg white lysozyme: a novel conformational change in antibody CDR-L3 selects for antigen.
    Braden BC; Fields BA; Ysern X; Goldbaum FA; Dall'Acqua W; Schwarz FP; Poljak RJ; Mariuzza RA
    J Mol Biol; 1996 Apr; 257(5):889-94. PubMed ID: 8632472
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
    Dall'Acqua W; Goldman ER; Lin W; Teng C; Tsuchiya D; Li H; Ysern X; Braden BC; Li Y; Smith-Gill SJ; Mariuzza RA
    Biochemistry; 1998 Jun; 37(22):7981-91. PubMed ID: 9609690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deriving topological constraints from functional data for the design of reagentless fluorescent immunosensors.
    Renard M; Belkadi L; Bedouelle H
    J Mol Biol; 2003 Feb; 326(1):167-75. PubMed ID: 12547199
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mutational analysis of the binding of two different proteins to the same antibody.
    Dall'Acqua W; Goldman ER; Eisenstein E; Mariuzza RA
    Biochemistry; 1996 Jul; 35(30):9667-76. PubMed ID: 8703938
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dissection of the IgNAR V domain: molecular scanning and orthologue database mining define novel IgNAR hallmarks and affinity maturation mechanisms.
    Fennell BJ; Darmanin-Sheehan A; Hufton SE; Calabro V; Wu L; Müller MR; Cao W; Gill D; Cunningham O; Finlay WJ
    J Mol Biol; 2010 Jul; 400(2):155-70. PubMed ID: 20450918
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting.
    Villani ME; Morea V; Consalvi V; Chiaraluce R; Desiderio A; Benvenuto E; Donini M
    Mol Immunol; 2008 May; 45(9):2474-85. PubMed ID: 18313757
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Affinity maturation increases the stability and plasticity of the Fv domain of anti-protein antibodies.
    Acierno JP; Braden BC; Klinke S; Goldbaum FA; Cauerhff A
    J Mol Biol; 2007 Nov; 374(1):130-46. PubMed ID: 17916365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies.
    Wang X; Campoli M; Ko E; Luo W; Ferrone S
    J Immunol Methods; 2004 Nov; 294(1-2):23-35. PubMed ID: 15604013
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme.
    Hawkins RE; Russell SJ; Baier M; Winter G
    J Mol Biol; 1993 Dec; 234(4):958-64. PubMed ID: 8263942
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Improving the stability of an antibody variable fragment by a combination of knowledge-based approaches: validation and mechanisms.
    Monsellier E; Bedouelle H
    J Mol Biol; 2006 Sep; 362(3):580-93. PubMed ID: 16926023
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.
    Staelens S; Desmet J; Ngo TH; Vauterin S; Pareyn I; Barbeaux P; Van Rompaey I; Stassen JM; Deckmyn H; Vanhoorelbeke K
    Mol Immunol; 2006 Mar; 43(8):1243-57. PubMed ID: 16118019
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of a phage library-derived single-chain Fv fragment complexed with turkey egg-white lysozyme at 2.0 A resolution.
    Aÿ J; Keitel T; Küttner G; Wessner H; Scholz C; Hahn M; Höhne W
    J Mol Biol; 2000 Aug; 301(2):239-46. PubMed ID: 10926506
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of the anti-His tag antibody 3D5 single-chain fragment complexed to its antigen.
    Kaufmann M; Lindner P; Honegger A; Blank K; Tschopp M; Capitani G; Plückthun A; Grütter MG
    J Mol Biol; 2002 Apr; 318(1):135-47. PubMed ID: 12054774
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional mapping and single chain construction of the anti-cytokeratin 8 monoclonal antibody TS1.
    Holm P; Jafari R; Sundström BE
    Mol Immunol; 2007 Feb; 44(6):1075-84. PubMed ID: 16989900
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional characterization of the somatic hypermutation process leading to antibody D1.3, a high affinity antibody directed against lysozyme.
    England P; Nageotte R; Renard M; Page AL; Bedouelle H
    J Immunol; 1999 Feb; 162(4):2129-36. PubMed ID: 9973487
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of interface framework residues in determining antibody V(H)/V(L) interaction strength and antigen-binding affinity.
    Masuda K; Sakamoto K; Kojima M; Aburatani T; Ueda T; Ueda H
    FEBS J; 2006 May; 273(10):2184-94. PubMed ID: 16649995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.