These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 12052175)

  • 1. The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease.
    Hooper NM; Turner AJ
    Curr Med Chem; 2002 Jun; 9(11):1107-19. PubMed ID: 12052175
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ADAMs family members as amyloid precursor protein alpha-secretases.
    Allinson TM; Parkin ET; Turner AJ; Hooper NM
    J Neurosci Res; 2003 Nov; 74(3):342-52. PubMed ID: 14598310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing.
    Camden JM; Schrader AM; Camden RE; González FA; Erb L; Seye CI; Weisman GA
    J Biol Chem; 2005 May; 280(19):18696-702. PubMed ID: 15778502
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S; Refolo LM; Sambamurti K
    J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase.
    Asai M; Hattori C; Szabó B; Sasagawa N; Maruyama K; Tanuma S; Ishiura S
    Biochem Biophys Res Commun; 2003 Jan; 301(1):231-5. PubMed ID: 12535668
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.
    Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
    Biochemistry; 1999 Jul; 38(30):9728-34. PubMed ID: 10423252
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme.
    Slack BE; Ma LK; Seah CC
    Biochem J; 2001 Aug; 357(Pt 3):787-94. PubMed ID: 11463349
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The non-amyloidogenic pathway: structure and function of alpha-secretases.
    Kojro E; Fahrenholz F
    Subcell Biochem; 2005; 38():105-27. PubMed ID: 15709475
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease.
    Lammich S; Kojro E; Postina R; Gilbert S; Pfeiffer R; Jasionowski M; Haass C; Fahrenholz F
    Proc Natl Acad Sci U S A; 1999 Mar; 96(7):3922-7. PubMed ID: 10097139
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network.
    Skovronsky DM; Moore DB; Milla ME; Doms RW; Lee VM
    J Biol Chem; 2000 Jan; 275(4):2568-75. PubMed ID: 10644715
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.
    Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
    Biochemistry; 1998 Feb; 37(6):1680-5. PubMed ID: 9484239
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein.
    Obregon DF; Rezai-Zadeh K; Bai Y; Sun N; Hou H; Ehrhart J; Zeng J; Mori T; Arendash GW; Shytle D; Town T; Tan J
    J Biol Chem; 2006 Jun; 281(24):16419-27. PubMed ID: 16624814
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of proteolysis in Alzheimer's disease.
    Hooper NM; Trew AJ; Parkin ET; Turner AJ
    Adv Exp Med Biol; 2000; 477():379-90. PubMed ID: 10849764
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
    Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
    Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein.
    Kojro E; Postina R; Buro C; Meiringer C; Gehrig-Burger K; Fahrenholz F
    FASEB J; 2006 Mar; 20(3):512-4. PubMed ID: 16401644
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An alternative secretase cleavage produces soluble Alzheimer amyloid precursor protein containing a potentially amyloidogenic sequence.
    Anderson JP; Chen Y; Kim KS; Robakis NK
    J Neurochem; 1992 Dec; 59(6):2328-31. PubMed ID: 1431910
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhancement of alpha-secretase cleavage of amyloid precursor protein by a metalloendopeptidase nardilysin.
    Hiraoka Y; Ohno M; Yoshida K; Okawa K; Tomimoto H; Kita T; Nishi E
    J Neurochem; 2007 Sep; 102(5):1595-1605. PubMed ID: 17555553
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain.
    Furukawa K; Sopher BL; Rydel RE; Begley JG; Pham DG; Martin GM; Fox M; Mattson MP
    J Neurochem; 1996 Nov; 67(5):1882-96. PubMed ID: 8863493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.
    Allinson TM; Parkin ET; Condon TP; Schwager SL; Sturrock ED; Turner AJ; Hooper NM
    Eur J Biochem; 2004 Jun; 271(12):2539-47. PubMed ID: 15182369
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding.
    Parvathy S; Ehrlich M; Pedrini S; Diaz N; Refolo L; Buxbaum JD; Bogush A; Petanceska S; Gandy S
    J Neurochem; 2004 Aug; 90(4):1005-10. PubMed ID: 15287907
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.