BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 12052500)

  • 1. Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay.
    Snyder RD; Arnone MR
    Mutat Res; 2002 Jun; 503(1-2):21-35. PubMed ID: 12052500
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of the clastogenic, DNA intercalative, and topoisomerase II-interactive properties of bioflavonoids in Chinese hamster V79 cells.
    Snyder RD; Gillies PJ
    Environ Mol Mutagen; 2002; 40(4):266-76. PubMed ID: 12489117
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of catalytic topoisomerase II inhibitors to probe mechanisms of chemical-induced clastogenicity in Chinese hamster V79 cells.
    Snyder RD
    Environ Mol Mutagen; 2000; 35(1):13-21. PubMed ID: 10692223
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evidence from studies with intact mammalian cells that merbarone and bis(dioxopiperazine)s are topoisomerase II poisons.
    Snyder RD
    Drug Chem Toxicol; 2003 Feb; 26(1):15-22. PubMed ID: 12643037
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reduction of genistein clastogenicity in Chinese hamster V79 cells by daidzein and other flavonoids.
    Snyder RD; Gillies PJ
    Food Chem Toxicol; 2003 Oct; 41(10):1291-8. PubMed ID: 12909261
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Further evidence that the radioprotective aminothiol, WR-1065, catalytically inactivates mammalian topoisomerase II.
    Snyder RD; Grdina DJ
    Cancer Res; 2000 Mar; 60(5):1186-8. PubMed ID: 10728671
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emodin triggers DNA double-strand breaks by stabilizing topoisomerase II-DNA cleavage complexes and by inhibiting ATP hydrolysis of topoisomerase II.
    Li Y; Luan Y; Qi X; Li M; Gong L; Xue X; Wu X; Wu Y; Chen M; Xing G; Yao J; Ren J
    Toxicol Sci; 2010 Dec; 118(2):435-43. PubMed ID: 20855424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutagenicity of some intercalating agents in Chinese hamster V79 cells.
    O'Donovan MR
    Mutat Res; 1984; 137(2-3):117-22. PubMed ID: 6472323
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of strong DNA-intercalating bioreductive compounds with topoisomerases I and II.
    Rosenzweig HS; Papadopoulou MV; Bloomer WD
    Oncol Res; 2005; 15(4):219-31. PubMed ID: 17822282
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhancement of bleomycin-induced micronucleus formation in V79 cells as a rapid and sensitive screen for non-covalent DNA-binding compounds.
    Snyder RD; Strekowski L
    Mutat Res; 1999 Jul; 444(1):181-92. PubMed ID: 10477353
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytogenetic evaluation of the mechanism of cell death induced by the novel anthracenyl-amino acid topoisomerase II catalytic inhibitor NU/ICRF 500.
    Cummings J; Sumner AT; Slavotinek A; Meikle I; Macpherson JS; Smyth JF
    Mutat Res; 1995 Aug; 344(1-2):55-62. PubMed ID: 7565893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA intercalative potential of marketed drugs testing positive in in vitro cytogenetics assays.
    Snyder RD; Ewing D; Hendry LB
    Mutat Res; 2006 Oct; 609(1):47-59. PubMed ID: 16857419
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia telangiectasia and Fanconi's anaemia cells.
    Jones NJ; Ellard S; Waters R; Parry EM
    Carcinogenesis; 1993 Dec; 14(12):2487-94. PubMed ID: 8269616
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Covalent attachment of ethidium to DNA results in enhanced topoisomerase II-mediated DNA cleavage.
    Marx G; Zhou H; Graves DE; Osheroff N
    Biochemistry; 1997 Dec; 36(50):15884-91. PubMed ID: 9398321
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence for and role of the dimethylamino group in tamoxifen DNA intercalation in intact Chinese hamster V79 cells.
    Snyder RD; Brown JE
    Drug Chem Toxicol; 2002 Nov; 25(4):473-9. PubMed ID: 12378953
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessment of atypical DNA intercalating agents in biological and in silico systems.
    Snyder RD
    Mutat Res; 2007 Oct; 623(1-2):72-82. PubMed ID: 17434187
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison.
    Xie CY; Zhu H; Lin LP; Miao ZH; Geng MY; Cai YJ; Chen Y; Zhao HJ; Luo HB; Zhang XW; Fan LM; Shen YM; Ding J
    Mol Cancer Ther; 2007 Nov; 6(11):3059-70. PubMed ID: 18025289
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potentiation of the mutagenicity and recombinagenicity of bleomycin in yeast by unconventional intercalating agents.
    Hoffmann GR; Laterza AM; Sylvia KE; Tartaglione JP
    Environ Mol Mutagen; 2011 Mar; 52(2):130-44. PubMed ID: 20839230
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes.
    Meng LH; Zhang JS; Ding J
    Biochem Pharmacol; 2001 Sep; 62(6):733-41. PubMed ID: 11551518
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex.
    Marshall KM; Holden JA; Koller A; Kashman Y; Copp BR; Barrows LR
    Anticancer Drugs; 2004 Oct; 15(9):907-13. PubMed ID: 15457132
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.