BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

386 related articles for article (PubMed ID: 12052824)

  • 1. Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity.
    Yu J; Lo JL; Huang L; Zhao A; Metzger E; Adams A; Meinke PT; Wright SD; Cui J
    J Biol Chem; 2002 Aug; 277(35):31441-7. PubMed ID: 12052824
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.
    Cui J; Huang L; Zhao A; Lew JL; Yu J; Sahoo S; Meinke PT; Royo I; Pelaez F; Wright SD
    J Biol Chem; 2003 Mar; 278(12):10214-20. PubMed ID: 12525500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bile salt excretory pump: biology and pathobiology.
    Suchy FJ; Ananthanarayanan M
    J Pediatr Gastroenterol Nutr; 2006 Jul; 43 Suppl 1():S10-6. PubMed ID: 16819395
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.
    Ananthanarayanan M; Balasubramanian N; Makishima M; Mangelsdorf DJ; Suchy FJ
    J Biol Chem; 2001 Aug; 276(31):28857-65. PubMed ID: 11387316
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.
    Schuetz EG; Strom S; Yasuda K; Lecureur V; Assem M; Brimer C; Lamba J; Kim RB; Ramachandran V; Komoroski BJ; Venkataramanan R; Cai H; Sinal CJ; Gonzalez FJ; Schuetz JD
    J Biol Chem; 2001 Oct; 276(42):39411-8. PubMed ID: 11509573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate.
    Cui J; Heard TS; Yu J; Lo JL; Huang L; Li Y; Schaeffer JM; Wright SD
    J Biol Chem; 2002 Jul; 277(29):25963-9. PubMed ID: 12004058
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.
    Deng R; Yang D; Yang J; Yan B
    J Pharmacol Exp Ther; 2006 Apr; 317(1):317-25. PubMed ID: 16371446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: dominance of transactivation over farsenoid X receptor-mediated antagonism.
    Deng R; Yang D; Radke A; Yang J; Yan B
    J Pharmacol Exp Ther; 2007 Mar; 320(3):1153-62. PubMed ID: 17135343
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.
    Hoeke MO; Plass JR; Heegsma J; Geuken M; van Rijsbergen D; Baller JF; Kuipers F; Moshage H; Jansen PL; Faber KN
    Hepatology; 2009 Jan; 49(1):151-9. PubMed ID: 19111018
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional analysis of the rat bile salt export pump gene promoter.
    Gerloff T; Geier A; Roots I; Meier PJ; Gartung C
    Eur J Biochem; 2002 Jul; 269(14):3495-503. PubMed ID: 12135489
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion.
    Lew JL; Zhao A; Yu J; Huang L; De Pedro N; Peláez F; Wright SD; Cui J
    J Biol Chem; 2004 Mar; 279(10):8856-61. PubMed ID: 14684751
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding.
    Kassam A; Miao B; Young PR; Mukherjee R
    J Biol Chem; 2003 Mar; 278(12):10028-32. PubMed ID: 12519787
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.
    Ananthanarayanan M; Li Y; Surapureddi S; Balasubramaniyan N; Ahn J; Goldstein JA; Suchy FJ
    Am J Physiol Gastrointest Liver Physiol; 2011 May; 300(5):G771-81. PubMed ID: 21330447
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump.
    Plass JR; Mol O; Heegsma J; Geuken M; Faber KN; Jansen PL; Müller M
    Hepatology; 2002 Mar; 35(3):589-96. PubMed ID: 11870371
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice.
    El Kasmi KC; Ghosh S; Anderson AL; Devereaux MW; Balasubramaniyan N; D'Alessandro A; Orlicky DJ; Suchy FJ; Shearn CT; Sokol RJ
    Hepatology; 2022 Feb; 75(2):252-265. PubMed ID: 34387888
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bile salt export pump is dysregulated with altered farnesoid X receptor isoform expression in patients with hepatocellular carcinoma.
    Chen Y; Song X; Valanejad L; Vasilenko A; More V; Qiu X; Chen W; Lai Y; Slitt A; Stoner M; Yan B; Deng R
    Hepatology; 2013 Apr; 57(4):1530-41. PubMed ID: 23213087
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor.
    Frankenberg T; Miloh T; Chen FY; Ananthanarayanan M; Sun AQ; Balasubramaniyan N; Arias I; Setchell KD; Suchy FJ; Shneider BL
    Hepatology; 2008 Dec; 48(6):1896-905. PubMed ID: 18668687
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Progressive familial intrahepatic cholestasis, type 1, is associated with decreased farnesoid X receptor activity.
    Chen F; Ananthanarayanan M; Emre S; Neimark E; Bull LN; Knisely AS; Strautnieks SS; Thompson RJ; Magid MS; Gordon R; Balasubramanian N; Suchy FJ; Shneider BL
    Gastroenterology; 2004 Mar; 126(3):756-64. PubMed ID: 14988830
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes.
    Balasubramaniyan N; Luo Y; Sun AQ; Suchy FJ
    J Biol Chem; 2013 May; 288(19):13850-62. PubMed ID: 23546875
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Geniposidic acid protected against ANIT-induced hepatotoxity and acute intrahepatic cholestasis, due to Fxr-mediated regulation of Bsep and Mrp2.
    Chen H; Huang X; Min J; Li W; Zhang R; Zhao W; Liu C; Yi L; Mi S; Wang N; Wang Q; Zhu C
    J Ethnopharmacol; 2016 Feb; 179():197-207. PubMed ID: 26723467
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.