195 related articles for article (PubMed ID: 12065613)
1. A non-amyloidogenic function of BACE-2 in the secretory pathway.
Fluhrer R; Capell A; Westmeyer G; Willem M; Hartung B; Condron MM; Teplow DB; Haass C; Walter J
J Neurochem; 2002 Jun; 81(5):1011-20. PubMed ID: 12065613
[TBL] [Abstract][Full Text] [Related]
2. Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles.
Hook VY; Toneff T; Aaron W; Yasothornsrikul S; Bundey R; Reisine T
J Neurochem; 2002 Apr; 81(2):237-56. PubMed ID: 12064471
[TBL] [Abstract][Full Text] [Related]
3. ELISA analysis of beta-secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways.
Steinhilb ML; Turner RS; Gaut JR
J Neurochem; 2002 Mar; 80(6):1019-28. PubMed ID: 11953452
[TBL] [Abstract][Full Text] [Related]
4. Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.
Shi XP; Tugusheva K; Bruce JE; Lucka A; Wu GX; Chen-Dodson E; Price E; Li Y; Xu M; Huang Q; Sardana MK; Hazuda DJ
J Biol Chem; 2003 Jun; 278(23):21286-94. PubMed ID: 12665519
[TBL] [Abstract][Full Text] [Related]
5. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
Farzan M; Schnitzler CE; Vasilieva N; Leung D; Choe H
Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9712-7. PubMed ID: 10931940
[TBL] [Abstract][Full Text] [Related]
6. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
Gandhi S; Refolo LM; Sambamurti K
J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
[TBL] [Abstract][Full Text] [Related]
7. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
8. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
[TBL] [Abstract][Full Text] [Related]
9. Glu11 site cleavage and N-terminally truncated A beta production upon BACE overexpression.
Liu K; Doms RW; Lee VM
Biochemistry; 2002 Mar; 41(9):3128-36. PubMed ID: 11863452
[TBL] [Abstract][Full Text] [Related]
10. The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity.
Fischer F; Molinari M; Bodendorf U; Paganetti P
J Neurochem; 2002 Mar; 80(6):1079-88. PubMed ID: 11953458
[TBL] [Abstract][Full Text] [Related]
11. Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that interfere with protein metabolism.
Tomita S; Kirino Y; Suzuki T
J Biol Chem; 1998 Mar; 273(11):6277-84. PubMed ID: 9497354
[TBL] [Abstract][Full Text] [Related]
12. Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.
Benjannet S; Elagoz A; Wickham L; Mamarbachi M; Munzer JS; Basak A; Lazure C; Cromlish JA; Sisodia S; Checler F; Chrétien M; Seidah NG
J Biol Chem; 2001 Apr; 276(14):10879-87. PubMed ID: 11152688
[TBL] [Abstract][Full Text] [Related]
13. Apical sorting of beta-secretase limits amyloid beta-peptide production.
Capell A; Meyn L; Fluhrer R; Teplow DB; Walter J; Haass C
J Biol Chem; 2002 Feb; 277(7):5637-43. PubMed ID: 11741885
[TBL] [Abstract][Full Text] [Related]
14. Identification of a beta-secretase activity, which truncates amyloid beta-peptide after its presenilin-dependent generation.
Fluhrer R; Multhaup G; Schlicksupp A; Okochi M; Takeda M; Lammich S; Willem M; Westmeyer G; Bode W; Walter J; Haass C
J Biol Chem; 2003 Feb; 278(8):5531-8. PubMed ID: 12471021
[TBL] [Abstract][Full Text] [Related]
15. Maturation and pro-peptide cleavage of beta-secretase.
Capell A; Steiner H; Willem M; Kaiser H; Meyer C; Walter J; Lammich S; Multhaup G; Haass C
J Biol Chem; 2000 Oct; 275(40):30849-54. PubMed ID: 10801872
[TBL] [Abstract][Full Text] [Related]
16. Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase.
Huse JT; Pijak DS; Leslie GJ; Lee VM; Doms RW
J Biol Chem; 2000 Oct; 275(43):33729-37. PubMed ID: 10924510
[TBL] [Abstract][Full Text] [Related]
17. Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network.
Skovronsky DM; Moore DB; Milla ME; Doms RW; Lee VM
J Biol Chem; 2000 Jan; 275(4):2568-75. PubMed ID: 10644715
[TBL] [Abstract][Full Text] [Related]
18. Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
Spoelgen R; von Arnim CA; Thomas AV; Peltan ID; Koker M; Deng A; Irizarry MC; Andersen OM; Willnow TE; Hyman BT
J Neurosci; 2006 Jan; 26(2):418-28. PubMed ID: 16407538
[TBL] [Abstract][Full Text] [Related]
19. Degradation of BACE by the ubiquitin-proteasome pathway.
Qing H; Zhou W; Christensen MA; Sun X; Tong Y; Song W
FASEB J; 2004 Oct; 18(13):1571-3. PubMed ID: 15289451
[TBL] [Abstract][Full Text] [Related]
20. GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing.
von Arnim CA; Spoelgen R; Peltan ID; Deng M; Courchesne S; Koker M; Matsui T; Kowa H; Lichtenthaler SF; Irizarry MC; Hyman BT
J Neurosci; 2006 Sep; 26(39):9913-22. PubMed ID: 17005855
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
