BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 12065748)

  • 1. Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system.
    Kimchi-Sarfaty C; Gribar JJ; Gottesman MM
    Mol Pharmacol; 2002 Jul; 62(1):1-6. PubMed ID: 12065748
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substrate-dependent effects of human ABCB1 coding polymorphisms.
    Gow JM; Hodges LM; Chinn LW; Kroetz DL
    J Pharmacol Exp Ther; 2008 May; 325(2):435-42. PubMed ID: 18287207
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system.
    Gribar JJ; Ramachandra M; Hrycyna CA; Dey S; Ambudkar SV
    J Membr Biol; 2000 Feb; 173(3):203-14. PubMed ID: 10667916
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.
    Ramachandra M; Ambudkar SV; Gottesman MM; Pastan I; Hrycyna CA
    Mol Biol Cell; 1996 Oct; 7(10):1485-98. PubMed ID: 8898356
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer.
    Fung KL; Pan J; Ohnuma S; Lund PE; Pixley JN; Kimchi-Sarfaty C; Ambudkar SV; Gottesman MM
    Cancer Res; 2014 Jan; 74(2):598-608. PubMed ID: 24305879
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Studies of human MDR1-MDR2 chimeras demonstrate the functional exchangeability of a major transmembrane segment of the multidrug transporter and phosphatidylcholine flippase.
    Zhou Y; Gottesman MM; Pastan I
    Mol Cell Biol; 1999 Feb; 19(2):1450-9. PubMed ID: 9891078
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition.
    Zhou SF
    Xenobiotica; 2008 Jul; 38(7-8):802-32. PubMed ID: 18668431
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prochloraz and nonylphenol diethoxylate inhibit an mdr1-like activity in vitro, but do not alter hepatic levels of P-glycoprotein in trout exposed in vivo.
    Sturm A; Cravedi JP; Segner H
    Aquat Toxicol; 2001 Aug; 53(3-4):215-28. PubMed ID: 11408081
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms.
    Meissner K; Jedlitschky G; Meyer zu Schwabedissen H; Dazert P; Eckel L; Vogelgesang S; Warzok RW; Böhm M; Lehmann C; Wendt M; Cascorbi I; Kroemer HK
    Pharmacogenetics; 2004 Jun; 14(6):381-5. PubMed ID: 15247630
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of the MDR1 gene and P-glycoprotein in canine mast cell tumor cell lines.
    Nakaichi M; Takeshita Y; Okuda M; Nakamoto Y; Itamoto K; Une S; Sasaki N; Kadosawa T; Takahashi T; Taura Y
    J Vet Med Sci; 2007 Feb; 69(2):111-5. PubMed ID: 17339753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional expression of P-glycoprotein in primary cultures of human cytotrophoblasts and BeWo cells.
    Utoguchi N; Chandorkar GA; Avery M; Audus KL
    Reprod Toxicol; 2000; 14(3):217-24. PubMed ID: 10838122
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Substrate- and species-dependent inhibition of P-glycoprotein-mediated transport: implications for predicting in vivo drug interactions.
    Zolnerciks JK; Booth-Genthe CL; Gupta A; Harris J; Unadkat JD
    J Pharm Sci; 2011 Aug; 100(8):3055-3061. PubMed ID: 21484807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines.
    Dey S; Patel J; Anand BS; Jain-Vakkalagadda B; Kaliki P; Pal D; Ganapathy V; Mitra AK
    Invest Ophthalmol Vis Sci; 2003 Jul; 44(7):2909-18. PubMed ID: 12824231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Influence of the G2677T/C3435T haplotype of MDR1 on P-glycoprotein trafficking and ibutilide-induced block of HERG.
    McBride BF; Yang T; Roden DM
    Pharmacogenomics J; 2009 Jun; 9(3):194-201. PubMed ID: 19204737
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance.
    Gekeler V; Boer R; Uberall F; Ise W; Schubert C; Utz I; Hofmann J; Sanders KH; Schächtele C; Klemm K; Grunicke H
    Br J Cancer; 1996 Sep; 74(6):897-905. PubMed ID: 8826855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A T3587G germ-line mutation of the MDR1 gene encodes a nonfunctional P-glycoprotein.
    Mutoh K; Mitsuhashi J; Kimura Y; Tsukahara S; Ishikawa E; Sai K; Ozawa S; Sawada J; Ueda K; Katayama K; Sugimoto Y
    Mol Cancer Ther; 2006 Apr; 5(4):877-84. PubMed ID: 16648557
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel MDR1 GT1292-3TG (Cys431Leu) genetic variation and its effect on P-glycoprotein biologic functions.
    Crouthamel MH; Wu D; Yang Z; Ho RJ
    AAPS J; 2010 Dec; 12(4):548-55. PubMed ID: 20623213
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.
    Tang-Wai DF; Kajiji S; DiCapua F; de Graaf D; Roninson IB; Gros P
    Biochemistry; 1995 Jan; 34(1):32-9. PubMed ID: 7819214
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MDR1 gene-related clonal selection and P-glycoprotein function and expression in relapsed or refractory acute myeloid leukemia.
    van den Heuvel-Eibrink MM; Wiemer EA; de Boevere MJ; van der Holt B; Vossebeld PJ; Pieters R; Sonneveld P
    Blood; 2001 Jun; 97(11):3605-11. PubMed ID: 11369657
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of ABC transporters on HIV-1 infection: inhibition of virus production by the MDR1 transporter.
    Lee CG; Ramachandra M; Jeang KT; Martin MA; Pastan I; Gottesman MM
    FASEB J; 2000 Mar; 14(3):516-22. PubMed ID: 10698967
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.