BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 12065752)

  • 1. NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype.
    Martini L; Hastrup H; Holst B; Fraile-Ramos A; Marsh M; Schwartz TW
    Mol Pharmacol; 2002 Jul; 62(1):30-7. PubMed ID: 12065752
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome".
    Jafri F; El-Shewy HM; Lee MH; Kelly M; Luttrell DK; Luttrell LM
    J Biol Chem; 2006 Jul; 281(28):19346-57. PubMed ID: 16670094
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for a role of caveolin-1 in neurokinin-1 receptor plasma-membrane localization, efficient signaling, and interaction with beta-arrestin 2.
    Kubale V; Abramović Z; Pogacnik A; Heding A; Sentjurc M; Vrecl M
    Cell Tissue Res; 2007 Nov; 330(2):231-45. PubMed ID: 17713785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biased Gs versus Gq proteins and β-arrestin signaling in the NK1 receptor determined by interactions in the water hydrogen bond network.
    Valentin-Hansen L; Frimurer TM; Mokrosinski J; Holliday ND; Schwartz TW
    J Biol Chem; 2015 Oct; 290(40):24495-508. PubMed ID: 26269596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis.
    Holst B; Hastrup H; Raffetseder U; Martini L; Schwartz TW
    J Biol Chem; 2001 Jun; 276(23):19793-9. PubMed ID: 11279104
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Receptor/beta-arrestin complex formation and the differential trafficking and resensitization of beta2-adrenergic and angiotensin II type 1A receptors.
    Anborgh PH; Seachrist JL; Dale LB; Ferguson SS
    Mol Endocrinol; 2000 Dec; 14(12):2040-53. PubMed ID: 11117533
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Point mutation increases a form of the NK1 receptor with high affinity for neurokinin A and B and septide.
    Ciucci A; Palma C; Manzini S; Werge TM
    Br J Pharmacol; 1998 Sep; 125(2):393-401. PubMed ID: 9786514
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substance P-induced trafficking of beta-arrestins. The role of beta-arrestins in endocytosis of the neurokinin-1 receptor.
    McConalogue K; Déry O; Lovett M; Wong H; Walsh JH; Grady EF; Bunnett NW
    J Biol Chem; 1999 Jun; 274(23):16257-68. PubMed ID: 10347182
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Divergent β-arrestin-dependent signaling events are dependent upon sequences within G-protein-coupled receptor C termini.
    Pal K; Mathur M; Kumar P; DeFea K
    J Biol Chem; 2013 Feb; 288(5):3265-74. PubMed ID: 23235155
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of a BRET2 screening assay using beta-arrestin 2 mutants.
    Vrecl M; Jorgensen R; Pogacnik A; Heding A
    J Biomol Screen; 2004 Jun; 9(4):322-33. PubMed ID: 15191649
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype.
    Jorgensen R; Martini L; Schwartz TW; Elling CE
    Mol Endocrinol; 2005 Mar; 19(3):812-23. PubMed ID: 15528268
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heterologous regulation of trafficking and signaling of G protein-coupled receptors: beta-arrestin-dependent interactions between neurokinin receptors.
    Schmidlin F; Déry O; Bunnett NW; Grady EF
    Proc Natl Acad Sci U S A; 2002 Mar; 99(5):3324-9. PubMed ID: 11880656
    [TBL] [Abstract][Full Text] [Related]  

  • 13. beta-Arrestin 1 and 2 stabilize the angiotensin II type I receptor in distinct high-affinity conformations.
    Sanni SJ; Hansen JT; Bonde MM; Speerschneider T; Christensen GL; Munk S; Gammeltoft S; Hansen JL
    Br J Pharmacol; 2010 Sep; 161(1):150-61. PubMed ID: 20718747
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Desensitization of the neurokinin-1 receptor (NK1-R) in neurons: effects of substance P on the distribution of NK1-R, Galphaq/11, G-protein receptor kinase-2/3, and beta-arrestin-1/2.
    McConalogue K; Corvera CU; Gamp PD; Grady EF; Bunnett NW
    Mol Biol Cell; 1998 Aug; 9(8):2305-24. PubMed ID: 9693383
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparison of tachykinin NK1 and NK2 receptors in the circular muscle of the guinea-pig ileum and proximal colon.
    Maggi CA; Patacchini R; Meini S; Quartara L; Sisto A; Potier E; Giuliani S; Giachetti A
    Br J Pharmacol; 1994 May; 112(1):150-60. PubMed ID: 7518302
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biased signaling of the angiotensin II type 1 receptor can be mediated through distinct mechanisms.
    Bonde MM; Hansen JT; Sanni SJ; Haunsø S; Gammeltoft S; Lyngsø C; Hansen JL
    PLoS One; 2010 Nov; 5(11):e14135. PubMed ID: 21152433
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor.
    Goodman OB; Krupnick JG; Santini F; Gurevich VV; Penn RB; Gagnon AW; Keen JH; Benovic JL
    Nature; 1996 Oct; 383(6599):447-50. PubMed ID: 8837779
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Split-receptors in the tachykinin neurokinin-1 system--mutational analysis of intracellular loop 3.
    Nielsen SM; Elling CE; Schwartz TW
    Eur J Biochem; 1998 Jan; 251(1-2):217-26. PubMed ID: 9492287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dissociation of beta-arrestin from internalized bradykinin B2 receptor is necessary for receptor recycling and resensitization.
    Simaan M; Bédard-Goulet S; Fessart D; Gratton JP; Laporte SA
    Cell Signal; 2005 Sep; 17(9):1074-83. PubMed ID: 15993749
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief.
    Jensen DD; Lieu T; Halls ML; Veldhuis NA; Imlach WL; Mai QN; Poole DP; Quach T; Aurelio L; Conner J; Herenbrink CK; Barlow N; Simpson JS; Scanlon MJ; Graham B; McCluskey A; Robinson PJ; Escriou V; Nassini R; Materazzi S; Geppetti P; Hicks GA; Christie MJ; Porter CJH; Canals M; Bunnett NW
    Sci Transl Med; 2017 May; 9(392):. PubMed ID: 28566424
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.