These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 12065753)

  • 21. Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98(3.36) of the human histamine H₄ receptor.
    Nijmeijer S; Engelhardt H; Schultes S; van de Stolpe AC; Lusink V; de Graaf C; Wijtmans M; Haaksma EE; de Esch IJ; Stachurski K; Vischer HF; Leurs R
    Br J Pharmacol; 2013 Sep; 170(1):89-100. PubMed ID: 23347159
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Histamine H4 receptor expression is elevated in human nasal polyp tissue.
    Jókúti A; Hellinger E; Hellinger A; Darvas Z; Falus A; Thurmond RL; Hirschberg A
    Cell Biol Int; 2007 Nov; 31(11):1367-70. PubMed ID: 17611128
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
    Liu C; Wilson SJ; Kuei C; Lovenberg TW
    J Pharmacol Exp Ther; 2001 Oct; 299(1):121-30. PubMed ID: 11561071
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Molecular cloning of monkey histamine H4 receptor.
    Oda T; Matsumoto S; Matsumoto M; Takasaki J; Kamohara M; Soga T; Hiyama H; Kobori M; Katoh M
    J Pharmacol Sci; 2005 Jul; 98(3):319-22. PubMed ID: 15968139
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Sodium binding to hH3R and hH 4R--a molecular modeling study.
    Wittmann HJ; Seifert R; Strasser A
    J Mol Model; 2014 Aug; 20(8):2394. PubMed ID: 25098339
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Human skin mast cells express H2 and H4, but not H3 receptors.
    Lippert U; Artuc M; Grützkau A; Babina M; Guhl S; Haase I; Blaschke V; Zachmann K; Knosalla M; Middel P; Krüger-Krasagakis S; Henz BM
    J Invest Dermatol; 2004 Jul; 123(1):116-23. PubMed ID: 15191551
    [TBL] [Abstract][Full Text] [Related]  

  • 27. cDNA cloning and characterization of porcine histamine H4 receptor.
    Oda T; Matsumoto S; Masuho Y; Takasaki J; Matsumoto M; Kamohara M; Saito T; Ohishi T; Soga T; Hiyama H; Matsushime H; Furuichi K
    Biochim Biophys Acta; 2002 May; 1575(1-3):135-8. PubMed ID: 12020829
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.
    Istyastono EP; Nijmeijer S; Lim HD; van de Stolpe A; Roumen L; Kooistra AJ; Vischer HF; de Esch IJ; Leurs R; de Graaf C
    J Med Chem; 2011 Dec; 54(23):8136-47. PubMed ID: 22003888
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structure-based discovery and binding site analysis of histamine receptor ligands.
    Kiss R; Keserű GM
    Expert Opin Drug Discov; 2016 Dec; 11(12):1165-1185. PubMed ID: 27704986
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structural and functional analysis of the canine histamine H2 receptor by site-directed mutagenesis: N-glycosylation is not vital for its action.
    Fukushima Y; Oka Y; Saitoh T; Katagiri H; Asano T; Matsuhashi N; Takata K; van Breda E; Yazaki Y; Sugano K
    Biochem J; 1995 Sep; 310 ( Pt 2)(Pt 2):553-8. PubMed ID: 7544576
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    Lim HD; van Rijn RM; Ling P; Bakker RA; Thurmond RL; Leurs R
    J Pharmacol Exp Ther; 2005 Sep; 314(3):1310-21. PubMed ID: 15947036
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Site-directed mutagenesis of the histamine H1 receptor: roles of aspartic acid107, asparagine198 and threonine194.
    Ohta K; Hayashi H; Mizuguchi H; Kagamiyama H; Fujimoto K; Fukui H
    Biochem Biophys Res Commun; 1994 Sep; 203(2):1096-101. PubMed ID: 8093027
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Modelling and mutation studies on the histamine H1-receptor agonist binding site reveal different binding modes for H1-agonists: Asp116 (TM3) has a constitutive role in receptor stimulation.
    ter Laak AM; Timmerman H; Leurs R; Nederkoorn PH; Smit MJ; Donné-Op den Kelder GM
    J Comput Aided Mol Des; 1995 Aug; 9(4):319-30. PubMed ID: 8523041
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.
    Thurmond RL; Desai PJ; Dunford PJ; Fung-Leung WP; Hofstra CL; Jiang W; Nguyen S; Riley JP; Sun S; Williams KN; Edwards JP; Karlsson L
    J Pharmacol Exp Ther; 2004 Apr; 309(1):404-13. PubMed ID: 14722321
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Cloning and characterization of a novel human histamine receptor.
    Morse KL; Behan J; Laz TM; West RE; Greenfeder SA; Anthes JC; Umland S; Wan Y; Hipkin RW; Gonsiorek W; Shin N; Gustafson EL; Qiao X; Wang S; Hedrick JA; Greene J; Bayne M; Monsma FJ
    J Pharmacol Exp Ther; 2001 Mar; 296(3):1058-66. PubMed ID: 11181941
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structural insights into the agonists binding and receptor selectivity of human histamine H
    Im D; Kishikawa JI; Shiimura Y; Hisano H; Ito A; Fujita-Fujiharu Y; Sugita Y; Noda T; Kato T; Asada H; Iwata S
    Nat Commun; 2023 Oct; 14(1):6538. PubMed ID: 37863901
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Site-directed mutagenesis of the histamine H1-receptor reveals a selective interaction of asparagine207 with subclasses of H1-receptor agonists.
    Leurs R; Smit MJ; Tensen CP; Ter Laak AM; Timmerman H
    Biochem Biophys Res Commun; 1994 May; 201(1):295-301. PubMed ID: 8198587
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands.
    Lee-Dutra A; Arienti KL; Buzard DJ; Hack MD; Khatuya H; Desai PJ; Nguyen S; Thurmond RL; Karlsson L; Edwards JP; Breitenbucher JG
    Bioorg Med Chem Lett; 2006 Dec; 16(23):6043-8. PubMed ID: 16990005
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Allergic inflammation is augmented via histamine H4 receptor activation: The role of natural killer cells in vitro and in vivo.
    Ehling S; Roßbach K; Dunston SM; Stark H; Bäumer W
    J Dermatol Sci; 2016 Aug; 83(2):106-15. PubMed ID: 27155791
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.
    Kiss R; Kiss B; Könczöl A; Szalai F; Jelinek I; László V; Noszál B; Falus A; Keseru GM
    J Med Chem; 2008 Jun; 51(11):3145-53. PubMed ID: 18459760
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.