BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 12067729)

  • 1. A point mutation at the subunit interface of hypoxanthine-guanine-xanthine phosphoribosyltransferase impairs activity: role of oligomerization in catalysis.
    Subbayya IN; Balaram H
    FEBS Lett; 2002 Jun; 521(1-3):72-6. PubMed ID: 12067729
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
    Sujay Subbayya IN; Sukumaran S; Shivashankar K; Balaram H
    Biochem Biophys Res Commun; 2000 Jun; 272(2):596-602. PubMed ID: 10833458
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for multiple active states of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
    Sujay Subbayya IN; Balaram H
    Biochem Biophys Res Commun; 2000 Dec; 279(2):433-7. PubMed ID: 11118304
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Slow ligand-induced conformational switch increases the catalytic rate in Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase.
    Roy S; Karmakar T; Prahlada Rao VS; Nagappa LK; Balasubramanian S; Balaram H
    Mol Biosyst; 2015 May; 11(5):1410-24. PubMed ID: 25824378
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of W181 in modulating kinetic properties of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase.
    Roy S; Karmakar T; Nagappa LK; Prahlada Rao VS; Balasubramanian S; Balaram H
    Proteins; 2016 Nov; 84(11):1658-1669. PubMed ID: 27479359
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of the flexible loop of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus in enzyme catalysis.
    Munagala N; Basus VJ; Wang CC
    Biochemistry; 2001 Apr; 40(14):4303-11. PubMed ID: 11284686
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
    Munagala NR; Wang CC
    Biochemistry; 1998 Nov; 37(47):16612-9. PubMed ID: 9843428
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purification and characterization of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase and comparison with the human enzyme.
    Keough DT; Ng AL; Winzor DJ; Emmerson BT; de Jersey J
    Mol Biochem Parasitol; 1999 Jan; 98(1):29-41. PubMed ID: 10029307
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetic mechanism of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
    Roy S; Nagappa LK; Prahladarao VS; Balaram H
    Mol Biochem Parasitol; 2015 Dec; 204(2):111-120. PubMed ID: 26902413
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetic Isotope Effects and Transition State Structure for Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase from Plasmodium falciparum.
    Ducati RG; Firestone RS; Schramm VL
    Biochemistry; 2017 Dec; 56(48):6368-6376. PubMed ID: 29131588
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interactions at the 2 and 5 positions of 5-phosphoribosyl pyrophosphate are essential in Salmonella typhimurium quinolinate phosphoribosyltransferase.
    Bello Z; Stitt B; Grubmeyer C
    Biochemistry; 2010 Feb; 49(7):1377-87. PubMed ID: 20047307
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biochemical characterization of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphorybosyltransferase: role of histidine residue in substrate selectivity.
    Sarkar D; Ghosh I; Datta S
    Mol Biochem Parasitol; 2004 Oct; 137(2):267-76. PubMed ID: 15383297
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase.
    Ullman B; Cyr N; Choi K; Jardim A
    Int J Biochem Cell Biol; 2010 Feb; 42(2):253-62. PubMed ID: 19861168
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
    Hazleton KZ; Ho MC; Cassera MB; Clinch K; Crump DR; Rosario I; Merino EF; Almo SC; Tyler PC; Schramm VL
    Chem Biol; 2012 Jun; 19(6):721-30. PubMed ID: 22726686
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemical and structural characterization of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Pyrococcus horikoshii.
    de Souza Dantas D; Ramos Dos Santos C; Guimarães Pereira GA; Medrano FJ
    Biochim Biophys Acta; 2008 Jun; 1784(6):953-60. PubMed ID: 18405676
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis.
    Page JP; Munagala NR; Wang CC
    Eur J Biochem; 1999 Feb; 259(3):565-71. PubMed ID: 10092838
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of a chimera of human and Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization.
    Gayathri P; Sujay Subbayya IN; Ashok CS; Selvi TS; Balaram H; Murthy MR
    Proteins; 2008 Dec; 73(4):1010-20. PubMed ID: 18536021
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum.
    Doyle PS; Kanaani J; Wang CC
    Exp Parasitol; 1998 May; 89(1):9-15. PubMed ID: 9603483
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism.
    Héroux A; White EL; Ross LJ; Davis RL; Borhani DW
    Biochemistry; 1999 Nov; 38(44):14495-506. PubMed ID: 10545171
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases.
    Keough DT; Skinner-Adams T; Jones MK; Ng AL; Brereton IM; Guddat LW; de Jersey J
    J Med Chem; 2006 Dec; 49(25):7479-86. PubMed ID: 17149876
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.