These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
253 related articles for article (PubMed ID: 12069166)
1. Analysis methods of polysorbate 20: A new method to assess the stability of polysorbate 20 and established methods that may overlook degraded polysorbate 20. Khossravi M; Kao YH; Mrsny RJ; Sweeney TD Pharm Res; 2002 May; 19(5):634-9. PubMed ID: 12069166 [TBL] [Abstract][Full Text] [Related]
2. Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation. Doshi N; Martin J; Tomlinson A Mol Pharm; 2020 Nov; 17(11):4354-4363. PubMed ID: 32941040 [TBL] [Abstract][Full Text] [Related]
3. Acidic and alkaline hydrolysis of polysorbates under aqueous conditions: Towards understanding polysorbate degradation in biopharmaceutical formulations. Dwivedi M; Buske J; Haemmerling F; Blech M; Garidel P Eur J Pharm Sci; 2020 Mar; 144():105211. PubMed ID: 31931121 [TBL] [Abstract][Full Text] [Related]
4. Controlled polysorbate 20 hydrolysis - A new approach to assess the impact of polysorbate 20 degradation on biopharmaceutical product quality in shortened time. Graf T; Abstiens K; Wedekind F; Elger C; Haindl M; Wurth C; Leiss M Eur J Pharm Biopharm; 2020 Jul; 152():318-326. PubMed ID: 32445968 [TBL] [Abstract][Full Text] [Related]
6. A Rapid High-Sensitivity Reversed-Phase Ultra High Performance Liquid Chromatography Mass Spectrometry Method for Assessing Polysorbate 20 Degradation in Protein Therapeutics. Cheng Y; Hu M; Zamiri C; Carcelen T; Demeule B; Tomlinson A; Gu J; Yigzaw Y; Kalo M; Yu XC J Pharm Sci; 2019 Sep; 108(9):2880-2886. PubMed ID: 31054888 [TBL] [Abstract][Full Text] [Related]
7. The degradation of polysorbates 20 and 80 and its potential impact on the stability of biotherapeutics. Kishore RS; Kiese S; Fischer S; Pappenberger A; Grauschopf U; Mahler HC Pharm Res; 2011 May; 28(5):1194-210. PubMed ID: 21369824 [TBL] [Abstract][Full Text] [Related]
8. Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways. Kerwin BA J Pharm Sci; 2008 Aug; 97(8):2924-35. PubMed ID: 17973307 [TBL] [Abstract][Full Text] [Related]
9. Novel markers to track oxidative polysorbate degradation in pharmaceutical formulations. Dahotre S; Tomlinson A; Lin B; Yadav S J Pharm Biomed Anal; 2018 Aug; 157():201-207. PubMed ID: 29803911 [TBL] [Abstract][Full Text] [Related]
10. Characterization and stability study of polysorbate 20 in therapeutic monoclonal antibody formulation by multidimensional ultrahigh-performance liquid chromatography-charged aerosol detection-mass spectrometry. Li Y; Hewitt D; Lentz YK; Ji JA; Zhang TY; Zhang K Anal Chem; 2014 May; 86(10):5150-7. PubMed ID: 24749737 [TBL] [Abstract][Full Text] [Related]
11. Quantitative determination of polysorbate 20 in nasal pharmaceutical preparations by high-performance liquid chromatography. Oszi Z; Pethö G J Pharm Biomed Anal; 1998 Dec; 18(4-5):715-20. PubMed ID: 9919973 [TBL] [Abstract][Full Text] [Related]
12. Characterization of polysorbate 80 with liquid chromatography mass spectrometry and nuclear magnetic resonance spectroscopy: specific determination of oxidation products of thermally oxidized polysorbate 80. Hvattum E; Yip WL; Grace D; Dyrstad K J Pharm Biomed Anal; 2012 Mar; 62():7-16. PubMed ID: 22260967 [TBL] [Abstract][Full Text] [Related]
13. Degradation Mechanisms of Polysorbate 20 Differentiated by Zhang L; Yadav S; Demeule B; Wang YJ; Mozziconacci O; Schӧneich C Pharm Res; 2017 Jan; 34(1):84-100. PubMed ID: 27738952 [TBL] [Abstract][Full Text] [Related]
14. A comparison of Polysorbates and Alternative Surfactants for Interfacial Stress Protection and Mitigation of Fatty Acid Particle Formation in the Presence of an Esterase. Roy I; Wuchner K; Stahl P; Tran T; Yaragudi N J Pharm Sci; 2024 Sep; 113(9):2688-2698. PubMed ID: 39009347 [TBL] [Abstract][Full Text] [Related]
15. Impact of mono- and poly-ester fractions on polysorbate quantitation using mixed-mode HPLC-CAD/ELSD and the fluorescence micelle assay. Lippold S; Koshari SHS; Kopf R; Schuller R; Buckel T; Zarraga IE; Koehn H J Pharm Biomed Anal; 2017 Jan; 132():24-34. PubMed ID: 27693757 [TBL] [Abstract][Full Text] [Related]
16. Investigation of excipients impact on polysorbate 80 degradation in biopharmaceutical formulation buffers. Bai L; Zhang Y; Zhang C; Lu Y; Li Z; Huang G; Meng B J Pharm Biomed Anal; 2023 Sep; 233():115496. PubMed ID: 37285658 [TBL] [Abstract][Full Text] [Related]
17. Development and validation of a selective marker-based quantification of polysorbate 20 in biopharmaceutical formulations using UPLC QDa detection. Evers DH; Schultz-Fademrecht T; Garidel P; Buske J J Chromatogr B Analyt Technol Biomed Life Sci; 2020 Nov; 1157():122287. PubMed ID: 33069954 [TBL] [Abstract][Full Text] [Related]
18. Polysorbate 20 Degradation in Biopharmaceutical Formulations: Quantification of Free Fatty Acids, Characterization of Particulates, and Insights into the Degradation Mechanism. Tomlinson A; Demeule B; Lin B; Yadav S Mol Pharm; 2015 Nov; 12(11):3805-15. PubMed ID: 26419339 [TBL] [Abstract][Full Text] [Related]
19. How enzymatic hydrolysis of polysorbate 20 influences colloidal protein stability. Glücklich N; Carle S; Diederichs T; Buske J; Mäder K; Garidel P Eur J Pharm Sci; 2023 Dec; 191():106597. PubMed ID: 37770006 [TBL] [Abstract][Full Text] [Related]
20. Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions. Glücklich N; Carle S; Buske J; Mäder K; Garidel P Eur J Pharm Sci; 2021 Nov; 166():105980. PubMed ID: 34419573 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]