BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

318 related articles for article (PubMed ID: 12070327)

  • 1. Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry.
    van den Bremer ET; Jiskoot W; James R; Moore GR; Kleanthous C; Heck AJ; Maier CS
    Protein Sci; 2002 Jul; 11(7):1738-52. PubMed ID: 12070327
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand-induced changes in the conformational dynamics of a bacterial cytotoxic endonuclease.
    van den Bremer ET; Keeble AH; Visser AJ; van Hoek A; Kleanthous C; Heck AJ; Jiskoot W
    Biochemistry; 2004 Apr; 43(14):4347-55. PubMed ID: 15065879
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multistep binding of transition metals to the H-N-H endonuclease toxin colicin E9.
    Keeble AH; Hemmings AM; James R; Moore GR; Kleanthous C
    Biochemistry; 2002 Aug; 41(32):10234-44. PubMed ID: 12162738
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specificity in protein-protein recognition: conserved Im9 residues are the major determinants of stability in the colicin E9 DNase-Im9 complex.
    Wallis R; Leung KY; Osborne MJ; James R; Moore GR; Kleanthous C
    Biochemistry; 1998 Jan; 37(2):476-85. PubMed ID: 9425068
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Calorimetric dissection of colicin DNase--immunity protein complex specificity.
    Keeble AH; Kirkpatrick N; Shimizu S; Kleanthous C
    Biochemistry; 2006 Mar; 45(10):3243-54. PubMed ID: 16519519
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Highly discriminating protein-protein interaction specificities in the context of a conserved binding energy hotspot.
    Li W; Keeble AH; Giffard C; James R; Moore GR; Kleanthous C
    J Mol Biol; 2004 Mar; 337(3):743-59. PubMed ID: 15019791
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Destabilization of the colicin E9 Endonuclease domain by interaction with negatively charged phospholipids: implications for colicin translocation into bacteria.
    Mosbahi K; Walker D; Lea E; Moore GR; James R; Kleanthous C
    J Biol Chem; 2004 May; 279(21):22145-51. PubMed ID: 15044477
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes.
    Kühlmann UC; Pommer AJ; Moore GR; James R; Kleanthous C
    J Mol Biol; 2000 Sep; 301(5):1163-78. PubMed ID: 10966813
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein-protein interactions in colicin E9 DNase-immunity protein complexes. 2. Cognate and noncognate interactions that span the millimolar to femtomolar affinity range.
    Wallis R; Leung KY; Pommer AJ; Videler H; Moore GR; James R; Kleanthous C
    Biochemistry; 1995 Oct; 34(42):13751-9. PubMed ID: 7577967
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Homing in on the role of transition metals in the HNH motif of colicin endonucleases.
    Pommer AJ; Kühlmann UC; Cooper A; Hemmings AM; Moore GR; James R; Kleanthous C
    J Biol Chem; 1999 Sep; 274(38):27153-60. PubMed ID: 10480931
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of critical residues in the colicin E9 DNase binding region of the Im9 protein.
    Osborne MJ; Wallis R; Leung KY; Williams G; Lian LY; James R; Kleanthous C; Moore GR
    Biochem J; 1997 May; 323 ( Pt 3)(Pt 3):823-31. PubMed ID: 9169618
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural dynamics of the membrane translocation domain of colicin E9 and its interaction with TolB.
    Collins ES; Whittaker SB; Tozawa K; MacDonald C; Boetzel R; Penfold CN; Reilly A; Clayden NJ; Osborne MJ; Hemmings AM; Kleanthous C; James R; Moore GR
    J Mol Biol; 2002 May; 318(3):787-804. PubMed ID: 12054823
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of putative active-site residues in the DNase domain of colicin E9 by random mutagenesis.
    Garinot-Schneider C; Pommer AJ; Moore GR; Kleanthous C; James R
    J Mol Biol; 1996 Aug; 260(5):731-42. PubMed ID: 8709151
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of conformational changes and noncovalent complexes of myoglobin by electrospray ionization mass spectrometry, circular dichroism and fluorescence spectroscopy.
    Lin X; Zhao W; Wang X
    J Mass Spectrom; 2010 Jun; 45(6):618-26. PubMed ID: 20527030
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual recognition and the role of specificity-determining residues in colicin E9 DNase-immunity protein interactions.
    Li W; Hamill SJ; Hemmings AM; Moore GR; James R; Kleanthous C
    Biochemistry; 1998 Aug; 37(34):11771-9. PubMed ID: 9718299
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein-protein interaction specificity of Im9 for the endonuclease toxin colicin E9 defined by homologue-scanning mutagenesis.
    Li W; Dennis CA; Moore GR; James R; Kleanthous C
    J Biol Chem; 1997 Aug; 272(35):22253-8. PubMed ID: 9268373
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein-protein interactions in colicin E9 DNase-immunity protein complexes. 1. Diffusion-controlled association and femtomolar binding for the cognate complex.
    Wallis R; Moore GR; James R; Kleanthous C
    Biochemistry; 1995 Oct; 34(42):13743-50. PubMed ID: 7577966
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vivo and in vitro characterization of overproduced colicin E9 immunity protein.
    Wallis R; Reilly A; Rowe A; Moore GR; James R; Kleanthous C
    Eur J Biochem; 1992 Jul; 207(2):687-95. PubMed ID: 1633820
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NMR investigation of the interaction of the inhibitor protein Im9 with its partner DNase.
    Boetzel R; Czisch M; Kaptein R; Hemmings AM; James R; Kleanthous C; Moore GR
    Protein Sci; 2000 Sep; 9(9):1709-18. PubMed ID: 11045617
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of protein-protein interaction surfaces using a combination of efficient lysine acetylation and nanoLC-MALDI-MS/MS applied to the E9:Im9 bacteriotoxin--immunity protein complex.
    Scholten A; Visser NFC; van den Heuvel RHH; Heck AJR
    J Am Soc Mass Spectrom; 2006 Jul; 17(7):983-994. PubMed ID: 16713291
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.