120 related articles for article (PubMed ID: 12074693)
1. Application of a colorimetric chain-termination assay for characterization of reverse transcriptase from 3'-azido-2',3'-deoxythymidine-resistant HIV isolates.
Shao XW; Hjalmarsson S; Lennerstrand J; Svennerholm B; Blomberg J; Källander CF; Gronowitz JS
Biotechnol Appl Biochem; 2002 Jun; 35(3):155-64. PubMed ID: 12074693
[TBL] [Abstract][Full Text] [Related]
2. The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Apr; 76(7):3248-56. PubMed ID: 11884549
[TBL] [Abstract][Full Text] [Related]
3. Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Canard B; Sarfati SR; Richardson CC
J Biol Chem; 1998 Jun; 273(23):14596-604. PubMed ID: 9603976
[TBL] [Abstract][Full Text] [Related]
4. Interactions of the HIV-1 reverse transcriptase 'AZT-resistant' mutant with substrates and AZT-TP.
Pokholok DK; Gudima SO; Yesipov DS; Dobrynin VN; Rechinsky VO; Kochetkov SN
FEBS Lett; 1993 Jul; 325(3):237-41. PubMed ID: 7686510
[TBL] [Abstract][Full Text] [Related]
5. Structural basis of HIV-1 resistance to AZT by excision.
Tu X; Das K; Han Q; Bauman JD; Clark AD; Hou X; Frenkel YV; Gaffney BL; Jones RA; Boyer PL; Hughes SH; Sarafianos SG; Arnold E
Nat Struct Mol Biol; 2010 Oct; 17(10):1202-9. PubMed ID: 20852643
[TBL] [Abstract][Full Text] [Related]
6. Relationship between 3'-azido-3'-deoxythymidine resistance and primer unblocking activity in foscarnet-resistant mutants of human immunodeficiency virus type 1 reverse transcriptase.
Meyer PR; Matsuura SE; Zonarich D; Chopra RR; Pendarvis E; Bazmi HZ; Mellors JW; Scott WA
J Virol; 2003 Jun; 77(11):6127-37. PubMed ID: 12743270
[TBL] [Abstract][Full Text] [Related]
7. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
Kerr SG; Anderson KS
Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
[TBL] [Abstract][Full Text] [Related]
8. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
[TBL] [Abstract][Full Text] [Related]
9. The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Selmi B; Deval J; Alvarez K; Boretto J; Sarfati S; Guerreiro C; Canard B
J Biol Chem; 2003 Oct; 278(42):40464-72. PubMed ID: 12902345
[TBL] [Abstract][Full Text] [Related]
10. Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3'-azido-3'-deoxythymidine (AZT)-resistant polymerase to AZT-5'-triphosphate.
Odriozola L; Cruchaga C; Andréola M; Dollé V; Nguyen CH; Tarrago-Litvak L; Pérez-Mediavilla A; Martínez-Irujo JJ
J Biol Chem; 2003 Oct; 278(43):42710-6. PubMed ID: 12917424
[TBL] [Abstract][Full Text] [Related]
11. pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo.
Eron JJ; Chow YK; Caliendo AM; Videler J; Devore KM; Cooley TP; Liebman HA; Kaplan JC; Hirsch MS; D'Aquila RT
Antimicrob Agents Chemother; 1993 Jul; 37(7):1480-7. PubMed ID: 7689822
[TBL] [Abstract][Full Text] [Related]
12. Implication of the tRNA initiation step for human immunodeficiency virus type 1 reverse transcriptase in the mechanism of 3'-azido-3'-deoxythymidine (AZT) resistance.
Vaccaro JA; Anderson KS
Biochemistry; 1998 Oct; 37(40):14189-94. PubMed ID: 9760256
[TBL] [Abstract][Full Text] [Related]
13. Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site.
Klarmann GJ; Smith RA; Schinazi RF; North TW; Preston BD
J Biol Chem; 2000 Jan; 275(1):359-66. PubMed ID: 10617626
[TBL] [Abstract][Full Text] [Related]
14. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2001 May; 75(10):4832-42. PubMed ID: 11312355
[TBL] [Abstract][Full Text] [Related]
15. Effects of beta-L-3'-azido-3'-deoxythymidine 5'-triphosphate on host and viral DNA polymerases.
Faraj A; El Alaoui AM; Gosselin G; Imbach JL; Morrow C; Sommadossi JP
Antiviral Res; 2000 Aug; 47(2):97-102. PubMed ID: 10996397
[TBL] [Abstract][Full Text] [Related]
16. A rapid phenotypic assay for detecting multiple nucleoside analogue reverse transcriptase inhibitor-resistant HIV-1 in plasma.
Qari SH; Winters M; Vandamme AM; Merigan T; Heneine W
Antivir Ther; 2002 Jun; 7(2):131-9. PubMed ID: 12212925
[TBL] [Abstract][Full Text] [Related]
17. Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance.
Im GJ; Tramontano E; Gonzalez CJ; Cheng YC
Biochem Pharmacol; 1993 Dec; 46(12):2307-13. PubMed ID: 7506027
[TBL] [Abstract][Full Text] [Related]
18. In vitro selection of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine.
Dianzani F; Antonelli G; Turriziani O; Dong G; Capobianchi MR; Riva E
Antiviral Res; 1992 May; 18(1):39-52. PubMed ID: 1384427
[TBL] [Abstract][Full Text] [Related]
19. Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA.
Sarafianos SG; Clark AD; Das K; Tuske S; Birktoft JJ; Ilankumaran P; Ramesha AR; Sayer JM; Jerina DM; Boyer PL; Hughes SH; Arnold E
EMBO J; 2002 Dec; 21(23):6614-24. PubMed ID: 12456667
[TBL] [Abstract][Full Text] [Related]
20. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
Periclou AP; Nandy P; Avramis VI
In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
