808 related articles for article (PubMed ID: 12077002)
1. Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis.
Menzies FM; Cookson MR; Taylor RW; Turnbull DM; Chrzanowska-Lightowlers ZM; Dong L; Figlewicz DA; Shaw PJ
Brain; 2002 Jul; 125(Pt 7):1522-33. PubMed ID: 12077002
[TBL] [Abstract][Full Text] [Related]
2. Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress.
Cookson MR; Menzies FM; Manning P; Eggett CJ; Figlewicz DA; McNeil CJ; Shaw PJ
Amyotroph Lateral Scler Other Motor Neuron Disord; 2002 Jun; 3(2):75-85. PubMed ID: 12215229
[TBL] [Abstract][Full Text] [Related]
3. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
[TBL] [Abstract][Full Text] [Related]
4. Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis.
Jung C; Higgins CM; Xu Z
J Neurochem; 2002 Nov; 83(3):535-45. PubMed ID: 12390515
[TBL] [Abstract][Full Text] [Related]
5. Characterization of the caspase cascade in a cell culture model of SOD1-related familial amyotrophic lateral sclerosis: expression, activation and therapeutic effects of inhibition.
Sathasivam S; Grierson AJ; Shaw PJ
Neuropathol Appl Neurobiol; 2005 Oct; 31(5):467-85. PubMed ID: 16150118
[TBL] [Abstract][Full Text] [Related]
6. Mitochondrial dynamics and bioenergetic dysfunction is associated with synaptic alterations in mutant SOD1 motor neurons.
Magrané J; Sahawneh MA; Przedborski S; Estévez ÁG; Manfredi G
J Neurosci; 2012 Jan; 32(1):229-42. PubMed ID: 22219285
[TBL] [Abstract][Full Text] [Related]
7. Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival.
Liu R; Li B; Flanagan SW; Oberley LW; Gozal D; Qiu M
J Neurochem; 2002 Feb; 80(3):488-500. PubMed ID: 11905995
[TBL] [Abstract][Full Text] [Related]
8. Differential gene expression in a cell culture model of SOD1-related familial motor neurone disease.
Kirby J; Menzies FM; Cookson MR; Bushby K; Shaw PJ
Hum Mol Genet; 2002 Aug; 11(17):2061-75. PubMed ID: 12165567
[TBL] [Abstract][Full Text] [Related]
9. Expression of a familial amyotrophic lateral sclerosis-associated mutant human superoxide dismutase in yeast leads to decreased mitochondrial electron transport.
Gunther MR; Vangilder R; Fang J; Beattie DS
Arch Biochem Biophys; 2004 Nov; 431(2):207-14. PubMed ID: 15488469
[TBL] [Abstract][Full Text] [Related]
10. CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations.
Jaarsma D; Rognoni F; van Duijn W; Verspaget HW; Haasdijk ED; Holstege JC
Acta Neuropathol; 2001 Oct; 102(4):293-305. PubMed ID: 11603803
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia causes autophagic stress and derangement of metabolic adaptation in a cell model of amyotrophic lateral sclerosis.
Cimini S; Rizzardini M; Biella G; Cantoni L
J Neurochem; 2014 May; 129(3):413-25. PubMed ID: 24359187
[TBL] [Abstract][Full Text] [Related]
12. Neurodegeneration induced by complex I inhibition in a cellular model of familial amyotrophic lateral sclerosis.
Rizzardini M; Lupi M; Mangolini A; Babetto E; Ubezio P; Cantoni L
Brain Res Bull; 2006 Apr; 69(4):465-74. PubMed ID: 16624679
[TBL] [Abstract][Full Text] [Related]
13. Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS.
Kirby J; Halligan E; Baptista MJ; Allen S; Heath PR; Holden H; Barber SC; Loynes CA; Wood-Allum CA; Lunec J; Shaw PJ
Brain; 2005 Jul; 128(Pt 7):1686-706. PubMed ID: 15872021
[TBL] [Abstract][Full Text] [Related]
14. Selective loss of neurofilament expression in Cu/Zn superoxide dismutase (SOD1) linked amyotrophic lateral sclerosis.
Menzies FM; Grierson AJ; Cookson MR; Heath PR; Tomkins J; Figlewicz DA; Ince PG; Shaw PJ
J Neurochem; 2002 Sep; 82(5):1118-28. PubMed ID: 12358759
[TBL] [Abstract][Full Text] [Related]
15. VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death.
Li B; Xu W; Luo C; Gozal D; Liu R
Brain Res Mol Brain Res; 2003 Mar; 111(1-2):155-64. PubMed ID: 12654515
[TBL] [Abstract][Full Text] [Related]
16. Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.
Urushitani M; Kurisu J; Tsukita K; Takahashi R
J Neurochem; 2002 Dec; 83(5):1030-42. PubMed ID: 12437574
[TBL] [Abstract][Full Text] [Related]
17. Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities.
Magrané J; Hervias I; Henning MS; Damiano M; Kawamata H; Manfredi G
Hum Mol Genet; 2009 Dec; 18(23):4552-64. PubMed ID: 19779023
[TBL] [Abstract][Full Text] [Related]
18. Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells.
Rizzardini M; Mangolini A; Lupi M; Ubezio P; Bendotti C; Cantoni L
J Neurol Sci; 2005 May; 232(1-2):95-103. PubMed ID: 15850589
[TBL] [Abstract][Full Text] [Related]
19. The effect of SOD1 mutation on cellular bioenergetic profile and viability in response to oxidative stress and influence of mutation-type.
Richardson K; Allen SP; Mortiboys H; Grierson AJ; Wharton SB; Ince PG; Shaw PJ; Heath PR
PLoS One; 2013; 8(6):e68256. PubMed ID: 23840839
[TBL] [Abstract][Full Text] [Related]
20. G37R SOD1 mutant alters mitochondrial complex I activity, Ca(2+) uptake and ATP production.
Coussee E; De Smet P; Bogaert E; Elens I; Van Damme P; Willems P; Koopman W; Van Den Bosch L; Callewaert G
Cell Calcium; 2011 Apr; 49(4):217-25. PubMed ID: 21388680
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
