BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 12077191)

  • 1. Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.
    Palfi S; Leventhal L; Chu Y; Ma SY; Emborg M; Bakay R; Déglon N; Hantraye P; Aebischer P; Kordower JH
    J Neurosci; 2002 Jun; 22(12):4942-54. PubMed ID: 12077191
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.
    Kordower JH; Emborg ME; Bloch J; Ma SY; Chu Y; Leventhal L; McBride J; Chen EY; Palfi S; Roitberg BZ; Brown WD; Holden JE; Pyzalski R; Taylor MD; Carvey P; Ling Z; Trono D; Hantraye P; Déglon N; Aebischer P
    Science; 2000 Oct; 290(5492):767-73. PubMed ID: 11052933
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intranigral ventral mesencephalic grafts and nigrostriatal injections of glial cell line-derived neurotrophic factor restore dopamine release in the striatum of 6-hydroxydopamine-lesioned rats.
    Tang FI; Tien LT; Zhou FC; Hoffer BJ; Wang Y
    Exp Brain Res; 1998 Apr; 119(3):287-96. PubMed ID: 9551829
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modification of the number and phenotype of striatal dopaminergic cells by carotid body graft.
    San Sebastián W; Guillén J; Manrique M; Belzunegui S; Ciordia E; Izal-Azcárate A; Garrido-Gil P; Vázquez-Claverie M; Luquin MR
    Brain; 2007 May; 130(Pt 5):1306-16. PubMed ID: 17439984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Long-term glial cell line-derived neurotrophic factor overexpression in the intact nigrostriatal system in rats leads to a decrease of dopamine and increase of tetrahydrobiopterin production.
    Sajadi A; Bauer M; Thöny B; Aebischer P
    J Neurochem; 2005 Jun; 93(6):1482-6. PubMed ID: 15935064
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin.
    Rosenblad C; Grønborg M; Hansen C; Blom N; Meyer M; Johansen J; Dagø L; Kirik D; Patel UA; Lundberg C; Trono D; Björklund A; Johansen TE
    Mol Cell Neurosci; 2000 Feb; 15(2):199-214. PubMed ID: 10673327
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model.
    Björklund A; Kirik D; Rosenblad C; Georgievska B; Lundberg C; Mandel RJ
    Brain Res; 2000 Dec; 886(1-2):82-98. PubMed ID: 11119690
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system.
    Rosenblad C; Georgievska B; Kirik D
    Eur J Neurosci; 2003 Jan; 17(2):260-70. PubMed ID: 12542662
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle.
    Rosenblad C; Kirik D; Devaux B; Moffat B; Phillips HS; Björklund A
    Eur J Neurosci; 1999 May; 11(5):1554-66. PubMed ID: 10215908
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration.
    Connor B; Kozlowski DA; Unnerstall JR; Elsworth JD; Tillerson JL; Schallert T; Bohn MC
    Exp Neurol; 2001 May; 169(1):83-95. PubMed ID: 11312561
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer.
    Georgievska B; Kirik D; Björklund A
    Exp Neurol; 2002 Oct; 177(2):461-74. PubMed ID: 12429192
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo.
    Kearns CM; Gash DM
    Brain Res; 1995 Feb; 672(1-2):104-11. PubMed ID: 7749731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.
    Xu G; Xiong Z; Yong Y; Wang Z; Ke Z; Xia Z; Hu Y
    Neuroscience; 2010 Apr; 167(1):174-84. PubMed ID: 20123001
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glial cell line-derived neurotrophic factor prevents death, but not reductions in tyrosine hydroxylase, of injured nigrostriatal neurons in adult rats.
    Lu X; Hagg T
    J Comp Neurol; 1997 Nov; 388(3):484-94. PubMed ID: 9368855
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration.
    Natsume A; Mata M; Goss J; Huang S; Wolfe D; Oligino T; Glorioso J; Fink DJ
    Exp Neurol; 2001 Jun; 169(2):231-8. PubMed ID: 11358438
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model.
    Rosenblad C; Kirik D; Björklund A
    Exp Neurol; 2000 Feb; 161(2):503-16. PubMed ID: 10686072
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged Parkinsonian rat.
    Connor B; Kozlowski DA; Schallert T; Tillerson JL; Davidson BL; Bohn MC
    Gene Ther; 1999 Dec; 6(12):1936-51. PubMed ID: 10637445
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.
    Georgievska B; Kirik D; Björklund A
    J Neurosci; 2004 Jul; 24(29):6437-45. PubMed ID: 15269253
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adenovirus-mediated transduction with human glial cell line-derived neurotrophic factor gene prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopamine depletion in striatum of mouse brain.
    Kojima H; Abiru Y; Sakajiri K; Watabe K; Ohishi N; Takamori M; Hatanaka H; Yagi K
    Biochem Biophys Res Commun; 1997 Sep; 238(2):569-73. PubMed ID: 9299553
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histological effects of intraputaminal infusion of glial cell line-derived neurotrophic factor in Parkinson disease model macaque monkeys.
    Oiwa Y; Nakai K; Itakura T
    Neurol Med Chir (Tokyo); 2006 Jun; 46(6):267-75; discussion 275-6. PubMed ID: 16794346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.