BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 12077346)

  • 1. Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair.
    Mahajan KN; Nick McElhinny SA; Mitchell BS; Ramsden DA
    Mol Cell Biol; 2002 Jul; 22(14):5194-202. PubMed ID: 12077346
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A biochemically defined system for mammalian nonhomologous DNA end joining.
    Ma Y; Lu H; Tippin B; Goodman MF; Shimazaki N; Koiwai O; Hsieh CL; Schwarz K; Lieber MR
    Mol Cell; 2004 Dec; 16(5):701-13. PubMed ID: 15574326
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ku recruits the XRCC4-ligase IV complex to DNA ends.
    Nick McElhinny SA; Snowden CM; McCarville J; Ramsden DA
    Mol Cell Biol; 2000 May; 20(9):2996-3003. PubMed ID: 10757784
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.
    Calsou P; Delteil C; Frit P; Drouet J; Salles B
    J Mol Biol; 2003 Feb; 326(1):93-103. PubMed ID: 12547193
    [TBL] [Abstract][Full Text] [Related]  

  • 5. APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation.
    Macrae CJ; McCulloch RD; Ylanko J; Durocher D; Koch CA
    DNA Repair (Amst); 2008 Feb; 7(2):292-302. PubMed ID: 18077224
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biochemical evidence for Ku-independent backup pathways of NHEJ.
    Wang H; Perrault AR; Takeda Y; Qin W; Wang H; Iliakis G
    Nucleic Acids Res; 2003 Sep; 31(18):5377-88. PubMed ID: 12954774
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction.
    Huang J; Dynan WS
    Nucleic Acids Res; 2002 Feb; 30(3):667-74. PubMed ID: 11809878
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polymerase μ in non-homologous DNA end joining: importance of the order of arrival at a double-strand break in a purified system.
    Zhao B; Watanabe G; Lieber MR
    Nucleic Acids Res; 2020 Apr; 48(7):3605-3618. PubMed ID: 32052035
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
    Hammel M; Yu Y; Radhakrishnan SK; Chokshi C; Tsai MS; Matsumoto Y; Kuzdovich M; Remesh SG; Fang S; Tomkinson AE; Lees-Miller SP; Tainer JA
    J Biol Chem; 2016 Dec; 291(53):26987-27006. PubMed ID: 27875301
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
    Teo SH; Jackson SP
    Curr Biol; 2000 Feb; 10(3):165-8. PubMed ID: 10679327
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks.
    Drouet J; Delteil C; Lefrançois J; Concannon P; Salles B; Calsou P
    J Biol Chem; 2005 Feb; 280(8):7060-9. PubMed ID: 15520013
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protection of telomeres by the Ku protein in fission yeast.
    Baumann P; Cech TR
    Mol Biol Cell; 2000 Oct; 11(10):3265-75. PubMed ID: 11029034
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA ends.
    Roberts SA; Ramsden DA
    J Biol Chem; 2007 Apr; 282(14):10605-13. PubMed ID: 17289670
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells.
    Verkaik NS; Esveldt-van Lange RE; van Heemst D; Brüggenwirth HT; Hoeijmakers JH; Zdzienicka MZ; van Gent DC
    Eur J Immunol; 2002 Mar; 32(3):701-9. PubMed ID: 11870614
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cooperative assembly of a protein-DNA filament for nonhomologous end joining.
    Tsai CJ; Chu G
    J Biol Chem; 2013 Jun; 288(25):18110-20. PubMed ID: 23620595
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks.
    Ramsden DA; Gellert M
    EMBO J; 1998 Jan; 17(2):609-14. PubMed ID: 9430651
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.
    Roberts SA; Strande N; Burkhalter MD; Strom C; Havener JM; Hasty P; Ramsden DA
    Nature; 2010 Apr; 464(7292):1214-7. PubMed ID: 20383123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural evidence for an in
    Loc'h J; Gerodimos CA; Rosario S; Tekpinar M; Lieber MR; Delarue M
    J Biol Chem; 2019 Jul; 294(27):10579-10595. PubMed ID: 31138645
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4.
    Mari PO; Florea BI; Persengiev SP; Verkaik NS; Brüggenwirth HT; Modesti M; Giglia-Mari G; Bezstarosti K; Demmers JA; Luider TM; Houtsmuller AB; van Gent DC
    Proc Natl Acad Sci U S A; 2006 Dec; 103(49):18597-602. PubMed ID: 17124166
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Non-histone chromosomal proteins HMG1 and 2 enhance ligation reaction of DNA double-strand breaks.
    Nagaki S; Yamamoto M; Yumoto Y; Shirakawa H; Yoshida M; Teraoka H
    Biochem Biophys Res Commun; 1998 May; 246(1):137-41. PubMed ID: 9600082
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.