BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 12079302)

  • 1. Microsatellite instability, MLH1 promoter methylation, and loss of mismatch repair in endometrial cancer and concomitant atypical hyperplasia.
    Horowitz N; Pinto K; Mutch DG; Herzog TJ; Rader JS; Gibb R; Bocker-Edmonston T; Goodfellow PJ
    Gynecol Oncol; 2002 Jul; 86(1):62-8. PubMed ID: 12079302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers.
    Simpkins SB; Bocker T; Swisher EM; Mutch DG; Gersell DJ; Kovatich AJ; Palazzo JP; Fishel R; Goodfellow PJ
    Hum Mol Genet; 1999 Apr; 8(4):661-6. PubMed ID: 10072435
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MSI in endometrial carcinoma: absence of MLH1 promoter methylation is associated with increased familial risk for cancers.
    Whelan AJ; Babb S; Mutch DG; Rader J; Herzog TJ; Todd C; Ivanovich JL; Goodfellow PJ
    Int J Cancer; 2002 Jun; 99(5):697-704. PubMed ID: 12115503
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Association of mismatch repair deficiency with PTEN frameshift mutations in endometrial cancers and the precursors in a Japanese population.
    Kanaya T; Kyo S; Sakaguchi J; Maida Y; Nakamura M; Takakura M; Hashimoto M; Mizumoto Y; Inoue M
    Am J Clin Pathol; 2005 Jul; 124(1):89-96. PubMed ID: 15923161
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MLH1 and MSH2 protein expression as a pre-screening marker in hereditary and non-hereditary endometrial hyperplasia and cancer.
    Berends MJ; Hollema H; Wu Y; van Der Sluis T; Mensink RG; ten Hoor KA; Sijmons RH; de Vries EG; Pras E; Mourits MJ; Hofstra RM; Buys CH; Kleibeuker JH; van Der Zee AG
    Int J Cancer; 2001 May; 92(3):398-403. PubMed ID: 11291077
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Methylation of hMLH1 in a population-based series of endometrial carcinomas.
    Salvesen HB; MacDonald N; Ryan A; Iversen OE; Jacobs IJ; Akslen LA; Das S
    Clin Cancer Res; 2000 Sep; 6(9):3607-13. PubMed ID: 10999752
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Frequent hypermethylation of MLH1 promoter in normal endometrium of patients with endometrial cancers.
    Kanaya T; Kyo S; Maida Y; Yatabe N; Tanaka M; Nakamura M; Inoue M
    Oncogene; 2003 Apr; 22(15):2352-60. PubMed ID: 12700670
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Microsatellite instability and MLH1 promoter methylation in human retinoblastoma.
    Choy KW; Pang CP; Fan DS; Lee TC; Wang JH; Abramson DH; Lo KW; To KF; Yu CB; Beaverson KL; Cheung KF; Lam DS
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3404-9. PubMed ID: 15452042
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas.
    Esteller M; Levine R; Baylin SB; Ellenson LH; Herman JG
    Oncogene; 1998 Nov; 17(18):2413-7. PubMed ID: 9811473
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Microsatellite instability and immunohistochemical analysis of MLH1 and MSH2 in normal endometrium, endometrial hyperplasia and endometrial cancer from a hereditary nonpolyposis colorectal cancer patient.
    Ichikawa Y; Tsunoda H; Takano K; Oki A; Yoshikawa H
    Jpn J Clin Oncol; 2002 Mar; 32(3):110-2. PubMed ID: 11956307
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Defective mismatch repair and the development of recurrent endometrial carcinoma.
    Pijnenborg JM; Dam-de Veen GC; de Haan J; van Engeland M; Groothuis PG
    Gynecol Oncol; 2004 Aug; 94(2):550-9. PubMed ID: 15297202
    [TBL] [Abstract][Full Text] [Related]  

  • 12. hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis.
    Esteller M; Catasus L; Matias-Guiu X; Mutter GL; Prat J; Baylin SB; Herman JG
    Am J Pathol; 1999 Nov; 155(5):1767-72. PubMed ID: 10550333
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genotypic and phenotypic progression in endometrial tumorigenesis: determining when defects in DNA mismatch repair and KRAS2 occur.
    Cohn DE; Mutch DG; Herzog TJ; Rader JS; Dintzis SM; Gersell DJ; Todd CR; Goodfellow PJ
    Genes Chromosomes Cancer; 2001 Dec; 32(4):295-301. PubMed ID: 11746970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers.
    Lawes DA; Pearson T; Sengupta S; Boulos PB
    Br J Cancer; 2005 Aug; 93(4):472-7. PubMed ID: 16106253
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid type.
    Zighelboim I; Goodfellow PJ; Gao F; Gibb RK; Powell MA; Rader JS; Mutch DG
    J Clin Oncol; 2007 May; 25(15):2042-8. PubMed ID: 17513808
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular characterization of endometrial cancer: a correlative study assessing microsatellite instability, MLH1 hypermethylation, DNA mismatch repair protein expression, and PTEN, PIK3CA, KRAS, and BRAF mutation analysis.
    Peterson LM; Kipp BR; Halling KC; Kerr SE; Smith DI; Distad TJ; Clayton AC; Medeiros F
    Int J Gynecol Pathol; 2012 May; 31(3):195-205. PubMed ID: 22498935
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High-resolution methylation analysis of the hMLH1 promoter in sporadic endometrial and colorectal carcinomas.
    Strazzullo M; Cossu A; Baldinu P; Colombino M; Satta MP; Tanda F; De Bonis ML; Cerase A; D'Urso M; D'Esposito M; Palmieri G
    Cancer; 2003 Oct; 98(7):1540-6. PubMed ID: 14508843
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tissue microarray immunohistochemical expression analysis of mismatch repair (hMLH1 and hMSH2 genes) in endometrial carcinoma and atypical endometrial hyperplasia: relationship with microsatellite instability.
    Hardisson D; Moreno-Bueno G; Sánchez L; Sarrió D; Suárez A; Calero F; Palacios J
    Mod Pathol; 2003 Nov; 16(11):1148-58. PubMed ID: 14614055
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study.
    Stefansson I; Akslen LA; MacDonald N; Ryan A; Das S; Jacobs IJ; Salvesen HB
    Clin Cancer Res; 2002 Jan; 8(1):138-43. PubMed ID: 11801550
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumours from HNPCC patients.
    de Leeuw WJ; Dierssen J; Vasen HF; Wijnen JT; Kenter GG; Meijers-Heijboer H; Brocker-Vriends A; Stormorken A; Moller P; Menko F; Cornelisse CJ; Morreau H
    J Pathol; 2000 Nov; 192(3):328-35. PubMed ID: 11054716
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.