BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 12082106)

  • 1. Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation.
    Pruitt K; Pruitt WM; Bilter GK; Westwick JK; Der CJ
    J Biol Chem; 2002 Aug; 277(35):31808-17. PubMed ID: 12082106
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta.
    Du J; Jiang B; Coffey RJ; Barnard J
    Mol Cancer Res; 2004 Apr; 2(4):233-41. PubMed ID: 15140945
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells.
    Oldham SM; Clark GJ; Gangarosa LM; Coffey RJ; Der CJ
    Proc Natl Acad Sci U S A; 1996 Jul; 93(14):6924-8. PubMed ID: 8692920
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ras mediates radioresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways.
    Grana TM; Rusyn EV; Zhou H; Sartor CI; Cox AD
    Cancer Res; 2002 Jul; 62(14):4142-50. PubMed ID: 12124353
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells.
    Pruitt K; Pestell RG; Der CJ
    J Biol Chem; 2000 Dec; 275(52):40916-24. PubMed ID: 11007784
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.
    Shields JM; Mehta H; Pruitt K; Der CJ
    Mol Cell Biol; 2002 Apr; 22(7):2304-17. PubMed ID: 11884615
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TC21 and Ras share indistinguishable transforming and differentiating activities.
    Graham SM; Oldham SM; Martin CB; Drugan JK; Zohn IE; Campbell S; Der CJ
    Oncogene; 1999 Mar; 18(12):2107-16. PubMed ID: 10321735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].
    Zhang YX; Kong CZ
    Zhonghua Yi Xue Za Zhi; 2008 Jan; 88(4):271-5. PubMed ID: 18361842
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ras-mediated intestinal epithelial cell transformation requires cyclooxygenase-2-induced prostaglandin E2 signaling.
    Repasky GA; Zhou Y; Morita S; Der CJ
    Mol Carcinog; 2007 Dec; 46(12):958-70. PubMed ID: 17477350
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Requirement for Ras/Raf/ERK pathway in naringin-induced G1-cell-cycle arrest via p21WAF1 expression.
    Kim DI; Lee SJ; Lee SB; Park K; Kim WJ; Moon SK
    Carcinogenesis; 2008 Sep; 29(9):1701-9. PubMed ID: 18296682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells.
    Gangarosa LM; Sizemore N; Graves-Deal R; Oldham SM; Der CJ; Coffey RJ
    J Biol Chem; 1997 Jul; 272(30):18926-31. PubMed ID: 9228072
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells.
    Plattner R; Gupta S; Khosravi-Far R; Sato KY; Perucho M; Der CJ; Stanbridge EJ
    Oncogene; 1999 Mar; 18(10):1807-17. PubMed ID: 10086335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of cytosolic phospholipase A2 by oncogenic Ras is mediated through the JNK and ERK pathways in rat epithelial cells.
    Van Putten V ; Refaat Z; Dessev C; Blaine S; Wick M; Butterfield L; Han SY; Heasley LE; Nemenoff RA
    J Biol Chem; 2001 Jan; 276(2):1226-32. PubMed ID: 11042196
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.
    Khosravi-Far R; White MA; Westwick JK; Solski PA; Chrzanowska-Wodnicka M; Van Aelst L; Wigler MH; Der CJ
    Mol Cell Biol; 1996 Jul; 16(7):3923-33. PubMed ID: 8668210
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a.
    Bulavin DV; Kovalsky O; Hollander MC; Fornace AJ
    Mol Cell Biol; 2003 Jun; 23(11):3859-71. PubMed ID: 12748288
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p38 Mitogen-activated protein kinase regulation of JB6 Cl41 cell transformation promoted by epidermal growth factor.
    He Z; Cho YY; Liu G; Ma WY; Bode AM; Dong Z
    J Biol Chem; 2003 Jul; 278(29):26435-42. PubMed ID: 12748197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor, SB203580.
    Kalmes A; Deou J; Clowes AW; Daum G
    FEBS Lett; 1999 Feb; 444(1):71-4. PubMed ID: 10037150
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Essential role of Raf in Ras transformation and deregulation of matrix metalloproteinase expression in ovarian epithelial cells.
    Ulkü AS; Schäfer R; Der CJ
    Mol Cancer Res; 2003 Dec; 1(14):1077-88. PubMed ID: 14707291
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of oocyte maturation by jun-N-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-MEK signal transduction pathway.
    Chie L; Amar S; Kung HF; Lin MC; Chen H; Chung DL; Adler V; Ronai Z; Friedman FK; Robinson RC; Kovac C; Brandt-Rauf PW; Yamaizumi Z; Michl J; Pincus MR
    Cancer Chemother Pharmacol; 2000; 45(6):441-9. PubMed ID: 10854130
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.