BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 12082462)

  • 1. Protocol for gene transduction and expansion of human T lymphocytes for clinical immunogene therapy of cancer.
    Lamers CH; Willemsen RA; Luider BA; Debets R; Bolhuis RL
    Cancer Gene Ther; 2002 Jul; 9(7):613-23. PubMed ID: 12082462
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Process validation and clinical evaluation of a protocol to generate gene-modified T lymphocytes for imunogene therapy for metastatic renal cell carcinoma: GMP-controlled transduction and expansion of patient's T lymphocytes using a carboxy anhydrase IX-specific scFv transgene.
    Lamers CH; van Elzakker P; Langeveld SC; Sleijfer S; Gratama JW
    Cytotherapy; 2006; 8(6):542-53. PubMed ID: 17148030
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional balance between T cell chimeric receptor density and tumor associated antigen density: CTL mediated cytolysis and lymphokine production.
    Weijtens ME; Hart EH; Bolhuis RL
    Gene Ther; 2000 Jan; 7(1):35-42. PubMed ID: 10680014
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Retronectin-assisted retroviral transduction of primary human T lymphocytes under good manufacturing practice conditions: tissue culture bag critically determines cell yield.
    Lamers CH; van Elzakker P; van Steenbergen SC; Sleijfer S; Debets R; Gratama JW
    Cytotherapy; 2008; 10(4):406-16. PubMed ID: 18574773
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A retroviral vector system 'STITCH' in combination with an optimized single chain antibody chimeric receptor gene structure allows efficient gene transduction and expression in human T lymphocytes.
    Weijtens ME; Willemsen RA; Hart EH; Bolhuis RL
    Gene Ther; 1998 Sep; 5(9):1195-203. PubMed ID: 9930320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene transfer of human TCR in primary murine T cells is improved by pseudo-typing with amphotropic and ecotropic envelopes.
    Pouw NM; Westerlaken EJ; Willemsen RA; Debets R
    J Gene Med; 2007 Jul; 9(7):561-70. PubMed ID: 17471588
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Optimization of lentiviral vector transduction into peripheral blood mononuclear cells in combination with the fibronectin fragment CH-296 stimulation.
    Chono H; Goto Y; Yamakawa S; Tanaka S; Tosaka Y; Nukaya I; Mineno J
    J Biochem; 2011 Mar; 149(3):285-92. PubMed ID: 21106541
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Parallel detection of transduced T lymphocytes after immunogene therapy of renal cell cancer by flow cytometry and real-time polymerase chain reaction: implications for loss of transgene expression.
    Lamers CH; Gratama JW; Pouw NM; Langeveld SC; Krimpen BA; Kraan J; Stoter G; Debets R
    Hum Gene Ther; 2005 Dec; 16(12):1452-62. PubMed ID: 16390276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heteroconjugate antibody-directed killing of autologous human renal carcinoma cells by in vitro-activated lymphocytes.
    Kerr L; Huntoon C; Donohue J; Leibson PJ; Bander NH; Ghose T; Luner SJ; Vessella R; McKean DJ
    J Immunol; 1990 May; 144(10):4060-7. PubMed ID: 2139677
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Establishment of an optimised gene transfer protocol for human primary T lymphocytes according to clinical requirements.
    Ayuk F; Li Z; Kühlcke K; Lindemann C; Schade U; Eckert HG; Zander A; Fehse B
    Gene Ther; 1999 Oct; 6(10):1788-92. PubMed ID: 10516731
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of B7.1 (CD80) in a renal cell carcinoma line allows expansion of tumor-associated cytotoxic T lymphocytes in the presence of an alloresponse.
    Schendel DJ; Frankenberger B; Jantzer P; Cayeux S; Nöbetaner E; Willimsky G; Maget B; Pohla H; Blankenstein T
    Gene Ther; 2000 Dec; 7(23):2007-14. PubMed ID: 11175312
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A phase I trial of CD3/CD28-activated T cells (Xcellerated T cells) and interleukin-2 in patients with metastatic renal cell carcinoma.
    Thompson JA; Figlin RA; Sifri-Steele C; Berenson RJ; Frohlich MW
    Clin Cancer Res; 2003 Sep; 9(10 Pt 1):3562-70. PubMed ID: 14506142
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Signal transduction abnormalities in T lymphocytes from patients with advanced renal carcinoma: clinical relevance and effects of cytokine therapy.
    Bukowski RM; Rayman P; Uzzo R; Bloom T; Sandstrom K; Peereboom D; Olencki T; Budd GT; McLain D; Elson P; Novick A; Finke JH
    Clin Cancer Res; 1998 Oct; 4(10):2337-47. PubMed ID: 9796963
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional impairment of human T-lymphocytes following PHA-induced expansion and retroviral transduction: implications for gene therapy.
    Duarte RF; Chen FE; Lowdell MW; Potter MN; Lamana ML; Prentice HG; Madrigal JA
    Gene Ther; 2002 Oct; 9(20):1359-68. PubMed ID: 12365001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phoenix-ampho outperforms PG13 as retroviral packaging cells to transduce human T cells with tumor-specific receptors: implications for clinical immunogene therapy of cancer.
    Lamers CH; Willemsen RA; van Elzakker P; van Krimpen BA; Gratama JW; Debets R
    Cancer Gene Ther; 2006 May; 13(5):503-9. PubMed ID: 16282986
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro activation of cancer patient-derived dendritic cells by tumor cells genetically modified to express CD154.
    Loskog A; Tötterman TH; Böhle A; Brandau S
    Cancer Gene Ther; 2002 Oct; 9(10):846-53. PubMed ID: 12224026
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Retrovirus-mediated gene transfer in human primary T lymphocytes induces an activation- and transduction/selection-dependent TCR-B variable chain repertoire skewing of gene-modified cells.
    Coito S; Sauce D; Duperrier A; Certoux JM; Bonyhadi M; Collette A; Kuehlcke K; Hervé P; Tiberghien P; Robinet E; Ferrand C
    Stem Cells Dev; 2004 Feb; 13(1):71-81. PubMed ID: 15068695
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ex vivo expansion of dendritic-cell-activated antigen-specific CD4+ T cells with anti-CD3/CD28, interleukin-7, and interleukin-15: potential for adoptive T cell immunotherapy.
    Chen HW; Liao CH; Ying C; Chang CJ; Lin CM
    Clin Immunol; 2006 Apr; 119(1):21-31. PubMed ID: 16406844
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Superior antitumor in vitro responses of allogeneic matched sibling compared with autologous patient CD8+ T cells.
    Kausche S; Wehler T; Schnürer E; Lennerz V; Brenner W; Melchior S; Gröne M; Nonn M; Strand S; Meyer R; Ranieri E; Huber C; Falk CS; Herr W
    Cancer Res; 2006 Dec; 66(23):11447-54. PubMed ID: 17145892
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-efficiency gene transfer into rhesus macaque primary T lymphocytes by combining 32 degrees C centrifugation and CH-296-coated plates: effect of gene transfer protocol on T cell homing receptor expression.
    Zhou P; Lee J; Moore P; Brasky KM
    Hum Gene Ther; 2001 Oct; 12(15):1843-55. PubMed ID: 11589827
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.